In:
Chemical Communications, Royal Society of Chemistry (RSC), Vol. 58, No. 9 ( 2022), p. 1314-1317
Abstract:
Cell-penetrating poly(disulfide)s (CPDs) are promising vehicles for cytosolic delivery of proteins. However, currently available arginine-rich CPD has rarely been reported for systemic delivery due to its “always” positive charge. Herein, we developed pH-responsive CPD IMD that executes tumor targeting delivery via protonation of imidazole groups within the acidic tumor microenvironment.
Type of Medium:
Online Resource
ISSN:
1359-7345
,
1364-548X
Language:
English
Publisher:
Royal Society of Chemistry (RSC)
Publication Date:
2022
detail.hit.zdb_id:
1472881-3
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