In:
Arquivos Brasileiros de Endocrinologia & Metabologia, FapUNIFESP (SciELO), Vol. 53, No. 1 ( 2009-02), p. 55-63
Abstract:
OBJECTIVE: Evaluate whether the increase of iodine in the diet would be the triggering factor for auto-immune thyropathies in the city of Santo André, SP. METHODS: Urinary iodine was determined in samples isolated from 58 patients, divided in 4 Groups, and in 13 normal individuals (controls). RESULTS: Urinary Iodine: Group 1 - hyperthyroidism = 203.5±152.71 µg/ L(mean±sd); Group 2 - hypothyroidism = 258.31±148,2 µg/L; Group 3 - chronic auto-immune thyroiditis = 244.29±191.6 µg/L; group 4 (Amiodarone) = 1157.5±261.8 µg/L; Group 5 - Controls = 262.31±146.2 µg/L. On comparing the means of urinary iodine among the groups, the means for groups 1, 2, 3, and 5 did not present significant differences (p 〉 0.05), and all differed from group 4 (p 〈 0.05). Urinary iodine obtained in groups 1, 2, 3 and 5, obtained in 2002-03, is not different from the values determined in students in 1994 in Santo André. CONCLUSION: This study shows evidence that iodine should not be considered as the responsible agent for auto-immune thyropathies in Santo André, and other environmental factors should be investigated.
Type of Medium:
Online Resource
ISSN:
0004-2730
DOI:
10.1590/S0004-27302009000100009
Language:
Unknown
Publisher:
FapUNIFESP (SciELO)
Publication Date:
2009
detail.hit.zdb_id:
2053068-7
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