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  • 1
    Online Resource
    Online Resource
    Value of p16 Expression in the Detection of High-Grade Squamous Intraepithelial Lesion of Cervix
    SASPR Edu International Pvt. Ltd ; 2023
    In:  Scholars Journal of Applied Medical Sciences Vol. 11, No. 1 ( 2023-01-30), p. 242-249
    Details
    In: Scholars Journal of Applied Medical Sciences, SASPR Edu International Pvt. Ltd, Vol. 11, No. 1 ( 2023-01-30), p. 242-249
    Abstract: Background: Cervical intraepithelial neoplasia (CIN) is usually a precancerous condition but, if left untreated, can develop into invasive cervical cancer. CIN2 and CIN3 are combinedly termed high-grade squamous intraepithelial lesions (HSIL). There are few screening tests based on cytology in detecting HSIL, but they are mostly less accurate. There is over-expression of p16 in pre-cancer and cancer of the cervix. The purpose of this study was to determine the value of p16 expression in the detection of HSIL. Methods: It was a cross-sectional study conducted in the colposcopy clinic of the Department of Obstetrics and Gynecology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, from October 2021 to March 2022. The study included 72 HSIL patients detected by colposcopy and had subsequent cervical biopsy and p16 immunohistochemistry. Results: Majority (45.8%) of the patients were found within the 30-39 years age group, 44.4% of the participants were illiterate, and 76.4% came from the middle-income group. Colposcopy-directed cervical Punch or Loop electrosurgical excision procedure (LEEP) biopsy revealed that 70.5% of patients had HSIL, and the rest (64.3%) suffered from LSIL. Positive p16 results were significantly higher among the HSIL group (84.1%) compared to those other than the HSIL group (3.6%) (p 〈 0.001). The sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of the p16 in the detection of HSIL were 84.1%, 96.4%, 79.4%, and 88.9%, respectively. Conclusions: Immunohistochemistry for p16 has a high diagnostic value in detecting HSIL patients. Therefore, this could be recommended for appropriate management of patients with CIN to avoid misdiagnosis and the over or under-treatment.
    Type of Medium: Online Resource
    ISSN: 2347-954X , 2320-6691
    URL: Article
    DOI: 10.36347/sjams.2023.v11i01.037
    Language: Unknown
    Publisher: SASPR Edu International Pvt. Ltd
    Publication Date: 2023
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  • 2
    Online Resource
    Online Resource
    Epidemiology of Vancomycin-Resistant Enterococci with Reduced Susceptibility to Daptomycin
    Cambridge University Press (CUP) ; 2012
    In:  Infection Control & Hospital Epidemiology Vol. 33, No. 12 ( 2012-12), p. 1250-1254
    Details
    In: Infection Control & Hospital Epidemiology, Cambridge University Press (CUP), Vol. 33, No. 12 ( 2012-12), p. 1250-1254
    Abstract: A retrospective case–case control study was conducted, including 60 cases with daptomycin-nonsusceptible vancomycin-resistant enterococci (DNS-VRE) matched to cases with daptomycin-susceptible VRE and to uninfected controls (1:1:3 ratio). Immunosuppression, presence of comorbid conditions, and prior exposure to antimicrobials were independent predictors of DNS-VRE, although prior daptomycin exposure occurred rarely. In summary, a case–case control study identified independent risk factors for the isolation of DNS-VRE: immunosuppression, multiple comorbid conditions, and prior exposures to cephalosporines and metronidazole.
    Type of Medium: Online Resource
    ISSN: 0899-823X , 1559-6834
    URL: Article
    DOI: 10.1086/668438
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2012
    detail.hit.zdb_id: 2106319-9
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  • 3
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    Breeding for the improvement of indigenous chickens of Bangladesh: evaluation of performance of first generation of indigenous chicken
    Bangladesh Academy of Sciences ; 2017
    In:  Asian Journal of Medical and Biological Research Vol. 3, No. 1 ( 2017-04-14), p. 72-79
    Details
    In: Asian Journal of Medical and Biological Research, Bangladesh Academy of Sciences, Vol. 3, No. 1 ( 2017-04-14), p. 72-79
    Abstract: Pure breeding is necessary for the conservation and improvement of indigenous chicken genetic resources. Present research is a part of the long-term selection program being undertaken to evaluate the performance and expected response to selection of first generation (G1) of three indigenous chicken genotypes under intensive management in Bangladesh. A total of 1439-day-old chicks comprising of 3 genotypes namely Naked Neck (NN), Hilly (H) and Non-descript Desi (ND) were hatched for this study. In first generation (G1), selection was practiced on body weight at 8 and 16 weeks of age, on the basis of their breeding value. At 40-week of age, selection will be practiced on the basis of an index comprising the parameters of age at first egg (ASM), body weight (BW), egg production (EP) and egg weight (EW). At 8, 10 and 12 weeks of age, six birds from each genotype were slaughtered to analyze the meat yield traits. Data were analyzed in CRD by General Linear Model Univariate Procedure. Significantly (P 〈 0.001) highest body weight of day-old chicks (28.65±0.12 g) and daily weight gain in all stages were found in H genotype than other two genotypes. Although there was significant (P 〈 0.001) difference in live weight between ages at slaughter, dressing percent (65.87 - 66.89 %) of different ages was similar (P 〉 0.05) but was affected (P 〈 0.001) by genotype. Body weight at 8 weeks of age was expected to improve by 58.98 vs. 11.50; 81.56 vs. 40.91 and 53.81 vs. 15.82 g; respectively for ND, H and NN males and females. In terms of body weight and growth traits H genotype was superior and NN genotype was for dressing percentage. As a result of selection; chick weight, body weight at all stages increased and ASM reduced in first generation than foundation stock. These findings give an impetus for continuing the pure breeding research for more generations.Asian J. Med. Biol. Res. March 2017, 3(1): 72-79
    Type of Medium: Online Resource
    ISSN: 2412-5571 , 2411-4472
    URL: Article
    DOI: 10.3329/ajmbr.v3i1.32039
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2017
    detail.hit.zdb_id: 2831390-2
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  • 4
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    Online Resource
    Breeding for the improvement of indigenous chickens of Bangladesh: performance of foundation stock
    Bangladesh Academy of Sciences ; 2017
    In:  Asian Journal of Medical and Biological Research Vol. 3, No. 1 ( 2017-04-14), p. 80-87
    Details
    In: Asian Journal of Medical and Biological Research, Bangladesh Academy of Sciences, Vol. 3, No. 1 ( 2017-04-14), p. 80-87
    Abstract: Selection is one of the vital tools for improving the indigenous chicken genetic resources. A total of 1585-day-old chicks comprising of 3 types of chicken namely Naked Neck (NN), Hilly (H) and Non-descript Deshi (ND) were hatched for this study to form foundation stock. Improvement target of egg weight was to increase by 1g and improvement target of egg production rate was to increase by 2 % per generation. In foundation stock, selection was practiced at 40-week of age, on the basis of an index comprising the parameters of age at first egg (ASM), body weight(BW), egg production(EP) and egg weight(EW). Data were analyzed in CRD by General Linear Model (GLM) Univariate Procedure. Significantly highest fertility (82.71%) and hatchability (82.20%) were found in ND genotype. Significantly (P 〈 0.001) highest body weight of day-old chicks and daily weight gain was found in H genotype than other two genotypes. There was a non-significant (P 〉 0.05) variation in FCR among the native chicken genotypes. NN genotype (3.46%) had non-significantly (?2 = 3.62; P 〉 0.05) higher chick mortality than ND (1.63%) and H (2.11%) at brooding period (0-4 weeks). Significantly (P 〈 0.01) higher dressing percentage was found in NN (64.58) genotype than ND (60.26) and H (61.70) genotypes. Non-significantly higher egg production in selected group was found in H (70) genotype than ND (68) and NN (67) genotypes. Significantly (P 〈 0.001) highest shape index and Haugh unit were found in H and ND genotypes, respectively. As a result of selection, egg production is expected to improve by 0.562, 0.932 and 0.755%, respectively for ND, H and NN genotypes. In terms of reproductive traits ND was superior, in terms of productive traits H genotype was superior and in terms of dressing percentage and breaking strength NN genotype was superior. These findings of the study also give an impetus for continuing the research for more generations to fulfill the objectives of the long-term programme.Asian J. Med. Biol. Res. March 2017, 3(1): 80-87
    Type of Medium: Online Resource
    ISSN: 2412-5571 , 2411-4472
    URL: Article
    DOI: 10.3329/ajmbr.v3i1.32041
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2017
    detail.hit.zdb_id: 2831390-2
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  • 5
    Online Resource
    Online Resource
    Incidence of Vitamin D Deficiency in Patients with Female Pattern Hair Loss (FPHL)
    Sciencedomain International ; 2021
    In:  Journal of Pharmaceutical Research International ( 2021-07-19), p. 48-53
    Details
    In: Journal of Pharmaceutical Research International, Sciencedomain International, ( 2021-07-19), p. 48-53
    Abstract: Background: Female pattern hair loss is also observed in women without increased androgen levels. Vitamin D is a factor that has recently been considered in dealing with these patients. Deficiency of Vitamin D might be correlated with diffuse hair loss. Objective: To determine the frequency of serum levels of Vitamin D3 in patients with female pattern of hair loss (FPHL) at tertiary care hospital Karachi. Methodology: This cross-sectional research was conducted upon a sample of 163 female patients (chosen via non-probability – consecutive sampling) presenting to the Dept. of Dermatology, Abbasi Shaheed Hospital, Karachi from 29th July 2018 to 28 th January 2019, with a clinical diagnosis of FPHL. Data was recorded onto a structured questionnaire containing inquiries pertaining to basic biodata, sociodemographic details, and inferences obtained from blood tests (CBC, serum ferritin, TSH level and vitamin D level). Serum 25 OH Vitamin D level 〈 20 was taken as deficient, 21-29 was insufficient and over 30 was sufficient. Data was analyzed using SPSS. v. 21.0. Results: The mean age was 30.39±6.36 years. Mean FPHL duration was 5.85±2.89 months. Total 63.2% patients were classified as mild, 26.45% patients were classified as moderate and 10.4% patients were classified as severe. Total 73% patients were found as vitamin D deficient, 22.1% as vitamin D insufficient and 4.9% as vitamin D sufficient. Significant association of vitamin D deficiency was observed with education status, vitamin D intake since past 6 months, and socio economic status. Conclusion: Results showed high vitamin D3 deficiency (73.0%) among patients with female pattern of hair loss (FPHL).
    Type of Medium: Online Resource
    ISSN: 2456-9119
    URL: Article
    DOI: 10.9734/jpri/2021/v33i37B32019
    Language: Unknown
    Publisher: Sciencedomain International
    Publication Date: 2021
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  • 6
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    Breeding for the improvement of indigenous chickens in Bangladesh: performance of second generation
    Bangladesh Academy of Sciences ; 2017
    In:  Asian Journal of Medical and Biological Research Vol. 3, No. 1 ( 2017-04-14), p. 66-71
    Details
    In: Asian Journal of Medical and Biological Research, Bangladesh Academy of Sciences, Vol. 3, No. 1 ( 2017-04-14), p. 66-71
    Abstract: The improvement of productivity of indigenous chicken is a long desire in the country. Present research is a part of the long-term selection program being undertaken to evaluate the carcass characteristics and expected response to selection of second generation (G2) of indigenous chicken under intensive management in Bangladesh. A total of 1643-day-old chicks comprising of 3 types of chicken namely Naked Neck (NN), Hilly (H) and Non-descript Desi (ND) were hatched in a two batches for this study. In second generation (G2), selection was practiced at 3 (three) stages of birds life, firstly and secondly at 8 and at 16 weeks of age, selection was performed on the basis of breeding value for 8 and 16 week body weight. Thirdly, at 40-week of age, on the basis of an index comprising the parameters of age at sexual maturity (ASM), body weight (BW), egg production (EP) and egg weight (EW). Improvement target of egg weight was to increase by 1g and improvement target of egg production rate was to increase by 2 % per generation. The main target was the mean body weight in H, ND and NN chicken has to be gone up from the initial eight-week body weight of 375, 342 and 331g to 500 g at eight weeks of age. At 8, 10 and 12 weeks of age, six birds from each genotype were slaughtered to analyze the meat yield traits. Slaughter data were analyzed in a 3(genotype)×3(slaughter age) factorial arrangement in CRD by General Linear Model (GLM) Univariate Procedure in SPSS Computer Program. Genotype and slaughter age had significant effect (p 〈 0.001) on dressing percentage. Body weight at 8 weeks of age was expected to improve by 51.21 vs. 24.03; 37.74 vs. 15.47 and 26.26 vs. 9.65g; respectively for ND, H and NN males and females. In terms of body weight H genotype was superior and NN genotype was for dressing percentage. As a result of selection; EP, BW increased and ASM reduced in second generation than that of the foundation stock.Asian J. Med. Biol. Res. March 2017, 3(1): 66-71
    Type of Medium: Online Resource
    ISSN: 2412-5571 , 2411-4472
    URL: Article
    DOI: 10.3329/ajmbr.v3i1.32038
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2017
    detail.hit.zdb_id: 2831390-2
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  • 7
    Online Resource
    Online Resource
    Cell cycle and clinical characteristics of patients with acute myeloid leukemia and myelodysplasia whose biopsies are reactive with anti-factor VIII antibody
    Elsevier BV ; 1991
    In:  Leukemia Research Vol. 15, No. 1 ( 1991-1), p. 51-57
    Details
    In: Leukemia Research, Elsevier BV, Vol. 15, No. 1 ( 1991-1), p. 51-57
    Type of Medium: Online Resource
    ISSN: 0145-2126
    URL: Article
    DOI: 10.1016/0145-2126(91)90144-I
    Language: English
    Publisher: Elsevier BV
    Publication Date: 1991
    detail.hit.zdb_id: 2008028-1
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  • 8
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    Productive and reproductive performances and expected response to selection of second generation of quail varieties conserved at Bangladesh Livestock Research Institute
    Bangladesh Academy of Sciences ; 2017
    In:  Asian Journal of Medical and Biological Research Vol. 2, No. 4 ( 2017-01-23), p. 631-634
    Details
    In: Asian Journal of Medical and Biological Research, Bangladesh Academy of Sciences, Vol. 2, No. 4 ( 2017-01-23), p. 631-634
    Abstract: Individual selection is particularly indispensable in selection experiments for body weight in quail. Body weight is highly heritable trait. The study was conducted with the objective to assess the productive and reproductive performance and expected response to selection of second generation (G2) of four quail varieties conserved at Bangladesh livestock Research Institute. At 5th week of age, quails of first generation (G1) were selected on the basis of breeding value according to their 5th week body weight. A total of 1953-day-old chicks were hatched in two batches for producing second generation (G2). Diet containing 24% crude protein and 3000 kcal ME/kg were provided to the birds. The data were analyzed in a CRD factorial arrangement by General Linear Model (GLM) Univariate Procedure in SPSS Computer Program. The highest fertility was observed in White (98.31%) variety and hatchability was in Japanese (97.75%) variety. Differences in chick weight at hatch between White and Brown, Brown and Japanese, Japanese and Black, Black and White were approximately 6.90%, 2.74%, 6.20% and 10.51% respectively. The effect of variety and batch on 5th week body weight was significant (p 〈 0.001) but interaction effect of variety and batch was not significant (p 〉 0.05). Black quail had significantly (?2 = 25.00; p 〈 0.01) higher (17.62%) chick mortality than that of other three varieties. As a result of selection, body weight at 5th weeks of age was expected to improve by 4.34g vs. 6.51g; 1.21g vs. 4.33g, 1.68g vs. 3.77g and 1.02g vs. 2.40g respectively for Japanese, White, Brown and Black males and females quail genotypes. It is therefore can be concluded that the White variety is superior in terms of higher body weight and higher fertility and medium chick mortality among the four quail varieties. In each generation, slight response was obtained for selection.Asian J. Med. Biol. Res. December 2016, 2(4): 631-634
    Type of Medium: Online Resource
    ISSN: 2412-5571 , 2411-4472
    URL: Article
    DOI: 10.3329/ajmbr.v2i4.31007
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2017
    detail.hit.zdb_id: 2831390-2
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  • 9
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    Conservation and improvement for the production of meat type quail in Bangladesh
    Bangladesh Academy of Sciences ; 2016
    In:  Asian-Australasian Journal of Bioscience and Biotechnology Vol. 1, No. 3 ( 2016-12-28), p. 425-428
    Details
    In: Asian-Australasian Journal of Bioscience and Biotechnology, Bangladesh Academy of Sciences, Vol. 1, No. 3 ( 2016-12-28), p. 425-428
    Abstract: The present study was conducted with the aim to develop a meat type quail genotype for our existing farming system. A total of 1866 quails from four genotypes namely Japanese, White, Black and Brown were used in the study for this purpose. The parent males and females were maintained in cages for single pair mating through close breeding system for producing each generation. Eggs were hatched in a batch for producing third generation (G3). Egg weight were significantly influenced (p 〈 0.05) by genotype. Highest egg weight was found in White (11.60±0.42) genotype followed by Japanese (10.35±0.30), Brown (10.30±0.42) and Black (9.78±0.65) quail genotypes. The highest hatchability of incubated eggs was found in Japanese (71.01%) genotype and lowest in Black (31.03%). White genotype of quail is significantly better for egg weight, chick weight and chick: egg ratio than that of their counterparts. Significantly higher body weight was found in Black (131.90 ± 1.24) genotype followed by White (131.86 ± 0.76), Brown (128.35 ±0.78) and Japanese (112.57 ± 0.53) quail genotype at different periods of age. Egg production was found significantly (p 〈 0.001) differed by genotypes. Black genotype was found highest (97.31±1.05%) while White genotype was found lowest (84.23±0.67%) performer in terms of egg production. It was concluded that the Black quail genotype can be used for meat type quail development in the country for its higher body weight and egg production. Asian Australas. J. Biosci. Biotechnol. 2016, 1 (3), 425-428
    Type of Medium: Online Resource
    ISSN: 2414-6293 , 2414-1283
    URL: Article
    DOI: 10.3329/aajbb.v1i3.63922
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2016
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  • 10
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    Online Resource
    Association of Metabolic Syndrome and Psoriasis
    Lahore Medical and Dental College ; 2022
    In:  Pakistan Journal of Medical and Health Sciences Vol. 16, No. 4 ( 2022-04-30), p. 1104-1106
    Details
    In: Pakistan Journal of Medical and Health Sciences, Lahore Medical and Dental College, Vol. 16, No. 4 ( 2022-04-30), p. 1104-1106
    Abstract: Objective: The objective of this study was to determine the association of metabolic syndrome and psoriasis Study Design: Case control study Settings: This study was conducted in Department of Dermatology in collaboration with Department of Chemical Pathology, PNS Shifa, Karachi. Duration of Study: Conducted for the duration of Six months from 1st July, 2020 to 30th December, 2020. Results: In our study, 67.39%(n=31) in cases and 76.09%(n=35) in Controls were between 20-35 years of age while 32.61%(n=15) in cases and 23.91%(n=11) in controls were between 36-50 years of age, mean+sd was calculated as 31.87+6.71 and 30.0+6.29 years respectively, 63.04%(n=29) in cases and 67.39%(n=31) in controls were male while 36.96%(n=17) in cases and 32.61%(n=15) in controls were females, frequency of association of metabolic syndrome and psoriasis was recorded as 56.52%(n=26) in cases and 32.61%(n=15) in controls had metabolic syndrome while 43.48%(n=20) in cases and 67.39%(n=31) in controls had no findings of metabolic syndrome, p value was calculated as 0.02 showing a significant difference. Conclusion: We concluded that the frequency of metabolic syndrome is higher among psoriasis cases when compared to the control cases. However, our significant results suggested that the physicians should periodically screen psoriatic patients for MetS and timely suggest medication or changes in lifestyle. Keywords: Psoriasis, Metabolic syndrome, Frequency
    Type of Medium: Online Resource
    URL: Issue
    URL: Journal
    URL: Article
    DOI: 10.53350/pjmhs22164
    DOI: 10.53350/pjmhs2216
    DOI: 10.53350/pjmhs221641104
    Language: Unknown
    Publisher: Lahore Medical and Dental College
    Publication Date: 2022
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