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  • 1
    In: Bangladesh Critical Care Journal, Bangladesh Academy of Sciences, Vol. 6, No. 2 ( 2018-10-15), p. 74-79
    Abstract: Background: Hypertension is a chronic and debilitating disease. Its complications are increasing all over the world, leading to life threatening medical problems like cardiovascular diseases, stroke and end stage renal diseases. An association between hyperlipidemia and hypertension has been identified.Objectives: The study was carried out to observe the association of serum low density lipoprotein cholesterol and high density lipoprotein cholesterol level with hypertension in adult female subjects.Method: This cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka, during the period of January 2011 to December 2011. A total number of sixty female subjects were selected with age ranging from30 to50 years. Among them 30 female subjects with hypertension were included from out-patient department of Medicine, Dhaka Medical College Hospital, Dhaka as study group(B) and 30 apparently healthy females were taken as control group(A) for comparison. Estimation of serum fasting serum low density lipoprotein cholesterol (LDL-C) and high density lipoprotein cholesterol (HDL-C) levels were done by enzymatic method in the Department of Physiology, Dhaka Medical College Dhaka in both groups. Systolic blood pressure and diastolic blood pressure of all participants were recorded by standard method. Data were analyzed by Unpaired Student’s- test and Pearson's correlation co-efficient (r) test as applicable.Result: The value of fasting serum LDL level was significantly higher in subjects with hypertension than those of control. Fasting serum HDL level was significantly lower in subjects with hypertension in comparison to control. In subjects with hypertension fasting serum LDL-C showed positive correlation with systolic and diastolic blood pressure and serum HDL-C showed negative correlation with systolic and diastolic blood pressure.Conclusion: Present study revealed that systolic and diastolic blood pressure has positive relationship with low density lipoprotein cholesterol (LDL-C) and negative relationship with high density lipoprotein cholesterol (HDL-C) levels.Bangladesh Crit Care J September 2018; 6(2): 74-79
    Type of Medium: Online Resource
    ISSN: 2307-7654 , 2304-0009
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2018
    detail.hit.zdb_id: 2852780-X
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  • 2
    In: Bangladesh Critical Care Journal, Bangladesh Academy of Sciences, Vol. 7, No. 1 ( 2019-03-27), p. 35-39
    Abstract: Hyperlipidemia is one of the most widespread medical disorder in female and its complications are increasing all over the world, leading to life threatening medical problems like cardiovascular diseases, stroke and peripheral vascular diseases. An association between hyperlipidemia and hypertension has been identified. The study was carried out to observe the association of serum triglycerides and total cholesterol level with hypertension in adult female subjects. This cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka, during the period of January 2011 to December 2011. A total number of sixty female subjects were selected with age ranging from 30 to 50 years. Among them 30 female subjects with hypertension were included from the out-patient department of Medicine, Dhaka Medical College Hospital, Dhaka as study group (B) and 30 apparently healthy females were taken as control group (A) for comparison. Estimation of fasting serum triglycerides (TG) and total cholesterol (TC) levels were done by enzymatic method in the Department of Physiology, Dhaka Medical College Dhaka in both groups. Systolic blood pressure and diastolic blood pressure of all participants were recorded by standard method. Data were analyzed by Unpaired Student’s- test and Pearson's correlation co-efficient (r) test as applicable. The values of fasting serum TG level were significantly higher in subjects with hypertension than those of control. Fasting serum TC level was significantly higher in subjects with hypertension in comparison to controls also. In subjects with hypertension fasting serum TG and fasting serum TC levels were higher and showed positive correlation with systolic and diastolic blood pressure. Present study revealed that systolic and diastolic blood pressure has positive relationship with fasting serum triglyceride (TG) and fasting serum cholesterol (TC) levels. Bangladesh Crit Care J March 2019; 7(1): 35-39
    Type of Medium: Online Resource
    ISSN: 2307-7654 , 2304-0009
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2019
    detail.hit.zdb_id: 2852780-X
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  • 3
    Online Resource
    Online Resource
    Frontiers Media SA ; 2019
    In:  Frontiers in Microbiology Vol. 10 ( 2019-11-7)
    In: Frontiers in Microbiology, Frontiers Media SA, Vol. 10 ( 2019-11-7)
    Type of Medium: Online Resource
    ISSN: 1664-302X
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2019
    detail.hit.zdb_id: 2587354-4
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  • 4
    In: Bangladesh Medical Journal, Bangladesh Academy of Sciences, Vol. 47, No. 3 ( 2019-10-10), p. 13-17
    Abstract: Cardiovascular diseases (CVDs) emerging as a major health problem in Bangladesh due to increase prevalence of risk factors. Conventional cardioprotective drugs are effective but expensive and associated with a number of side effects. Curcuma longa is an important source of traditional medicine for the prevention and treatment of CVDs. The objective of the study was to evaluate the protective effect of Curcuma longa on isoproterenol induced myocardial injury in rats. This experimental study was carried out in the Department of Physiology, Dhaka Medical College, Dhaka during 2015. Total 21 Wistar albino male rats, aged 85 to 100 days, weighing 100 to 150 g (initial body weight) were selected for the study. After acclimatization for 14 days, the rats were divided into three groups. Group A (base line control group), Group B (isoproterenol treated control group) and Group C (Curcuma longa pretreated and isoproterenol treated group). Each group consisted of 7 rats. On the 10th day of experiment, rats were sacrificed after taking final body weight. Blood samples were collected from the heart. Serum aspartate aminotransferase (AST) level was estimated by Colorimetric method and lactate dehydrogenase (LDH) level was estimated by ELISA method. The statistical analysis was done by one way ANOVA and Bonferroni test as applicable.  In this study, the mean initial and final body weight of the rats were almost similar and showed no statistically significant difference among the groups. The mean serum AST and LDH levels were significantly (P 〈 0.001) higher in Group B than those of Group A. Again, these levels were significantly (P 〈 0.001) lower in Group C than those of Group B group. From the results, it can be concluded that Curcuma longa has cardioprotective activity on isoproterenol induced myocardial injury in Wistar albino rats. Bangladesh Med J. 2018 Jan; 47 (3): 13-17
    Type of Medium: Online Resource
    ISSN: 2219-1607 , 0301-035X
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2019
    detail.hit.zdb_id: 2549257-3
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  • 5
    Online Resource
    Online Resource
    Bangladesh Academy of Sciences ; 2017
    In:  Bangladesh Journal of Medicine Vol. 28, No. 1 ( 2017-03-16), p. 28-33
    In: Bangladesh Journal of Medicine, Bangladesh Academy of Sciences, Vol. 28, No. 1 ( 2017-03-16), p. 28-33
    Abstract: Background: Incidence of hypertension in female is increasing throughout the world, leading to life threatening medical problem like cardiovascular diseases, stroke. An association between hypertension and obesity has been identified.Objectives : The study was carried out to observe the association of obesity with hypertension in adult female.Methods : This cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka, during the period of January 2011 to December 2011. A total number of one hundred female subjects were selected with age ranging from30 to50 years. Among them 50 hypertensive female subjects were included from out-patient department of Medicine, Dhaka medical college Hospital, Dhaka as study group(B) and 50 apparently healthy female were taken as control group(A) for comparison Waist circumference(WC) was measured and body mass index (BMI) was calculated in both groups. Data was analyzed by Unpaired Students t test and Pearsons correlation co-efficient (r) test as applicable.Results: The value of waist circumference was higher in hypertensive subjects than those of nonhypertensive female and result was statistically significant. Body mass index value was significantly (p 〈 0.001) higher in hypertensive subjects in comparison to those of non-hypertensive subjects. In hypertensive subjects waist circumference and body mass index values were higher and showed significant positive correlation with systolic and diastolic blood pressure. Conclusion: Present study revealed that hypertension has positive and significant relationship with waist circumference and body mass index.Bangladesh J Medicine Jan 2017; 28(1) : 28-33
    Type of Medium: Online Resource
    ISSN: 2408-8366 , 1023-1986
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2017
    detail.hit.zdb_id: 2853118-8
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  • 6
    In: Journal of Dhaka Medical College, Bangladesh Academy of Sciences, Vol. 27, No. 2 ( 2020-03-10), p. 148-154
    Abstract: Diabetes mellitus is one of the most widespread endocrine disorder in female and its complications are increasing all over the world, leading to life threatening medical problems like cardiovascular diseases, stroke and end stage renal diseases. A relation between hyperlipidemia and diabetes mellitus has been identified. The study was carried out to observe the serum triglycerides and total cholesterol levels its relation with type 2 diabetes mellitus in adult female subjects. This cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka, during the period of January 2011 to December 2011. A total number of sixty female subjects were selected with age ranging from30 to50 years. Among them 30 female subjects with diabetes were included from out-patient department of Endocrinology, Dhaka Medical College Hospital, Dhaka as study group(B) and 30 apparently healthy female were taken as control group(A) for comparison. Estimation of fasting serum triglycerides (TG) and total cholesterol (TC) levels were done by enzymatic method in the Department of Physiology, Dhaka Medical College Dhaka in both groups. Fasting serum insulin level was measured by ELISA method in the Department of Laboratory of National Institute of ENT, Dhaka and fasting blood glucose was estimated by glucose oxidase method in Department of Dhaka Medical College in both groups. Data were analyzed by Unpaired Student’s- test and Pearson’s correlation co-efficient (r) test as applicable. The value of fasting serum TG and TC level were significantly higher in study subjects than those of control. In study subjects fasting serum TG and fasting serum TC levels showed positive correlation with fasting blood glucose and serum insulin level. Conclusion: Present study revealed that fasting serum triglyceride (TG) and fasting serum cholesterol (TC) levels have positive relationship with fasting serum insulin and fasting blood glucose levels. J Dhaka Medical College, Vol. 27, No.2, October, 2018, Page 148-154
    Type of Medium: Online Resource
    ISSN: 2219-7494 , 1028-0928
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2020
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  • 7
    In: Journal of Dhaka Medical College, Bangladesh Academy of Sciences, Vol. 26, No. 2 ( 2018-11-18), p. 140-147
    Abstract: Background: Diabetes mellitus is one of the most widespread endocrine disorders in female and its complications are increasing all over the world, leading to life threatening medical problems like cardiovascular diseases, stroke and end stage renal diseases. A correlation between hyperlipidemia and type 2 diabetes mellitus has been identified. The study was carried out to observe the correlation of serum low density lipoprotein cholesterol (LDL-C) and high density lipoprotein cholesterol (HDL-C) level with type 2 diabetes mellitus in adult female subjects.Method: This cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka, during the period of January 2011 to December 2011. Total sixty female subjects were selected with age ranging from 30 to 50 years. Among them 30 female subjects with diabetes mellitus were included from out-patient department of Endocrinology, Dhaka Medical College Hospital, Dhaka as study group (B) and 30 apparently healthy females were taken as control group (A) for comparison. Estimation of serum fasting serum LDL-C and HDL-C levels was done by enzymatic method in the department of Physiology, Dhaka Medical College Dhaka in both groups. Fasting serum insulin level was measured by ELISA method in the laboratory of National Institute of ENT, Dhaka and fasting blood glucose was estimated by glucose oxidase method in the department of Physiology, Dhaka Medical College in both groups. Data were analyzed by Unpaired Student’s- test and Pearson’s correlation co-efficient (r) test as applicable.Results: The value of fasting serum LDL-C level was significantly higher in study subjects than those of control. Again, fasting serum HDL-C level was significantly lower in study subjects in comparison to controls. In study subjects fasting serum LDL showed positive correlation and fasting serum HDL-C levels showed negative correlation with fasting blood glucose and serum insulin level.Conclusion: Present study reveals that serum insulin and blood glucose level have positive relationship with low density lipoprotein cholesterol (LDL-C) and negative relationship with high density lipoprotein cholesterol (HDL-C) levels.J Dhaka Medical College, Vol. 26, No.2, October, 2017, Page 140-147
    Type of Medium: Online Resource
    ISSN: 2219-7494 , 1028-0928
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2018
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  • 8
    In: ACS Chemical Neuroscience, American Chemical Society (ACS), Vol. 12, No. 16 ( 2021-08-18), p. 3112-3123
    Type of Medium: Online Resource
    ISSN: 1948-7193 , 1948-7193
    Language: English
    Publisher: American Chemical Society (ACS)
    Publication Date: 2021
    detail.hit.zdb_id: 2528493-9
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  • 9
    Online Resource
    Online Resource
    Bangladesh Academy of Sciences ; 2017
    In:  Bangladesh Medical Journal Vol. 46, No. 1 ( 2017-11-21), p. 32-37
    In: Bangladesh Medical Journal, Bangladesh Academy of Sciences, Vol. 46, No. 1 ( 2017-11-21), p. 32-37
    Abstract: Hyperglycemia is a major risk factor for cardiovascular diseases in postmenopausal women. Increased incidence of cardiovascular diseases in postmenopausal women may be due to hyperglycemia caused by lower level of estrogen hormone. This cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka, Bangladesh during the period of January to December 2011 to observe the correlation of estrogen with fasting serum insulin (FSI) and fasting blood glucose (FBG) levels in postmenopausal women. A total of 90 women were selected from different areas of Dhaka city, among them, 60 postmenopausal women of age group 50 to 60 years were taken as study group and 30 apparently healthy premenopausal women of age group 20 to 30 years were included as comparison group. The study parameters fasting blood glucose level was estimated by enzymatic method in both groups. Serum insulin level was estimated by Enzyme Linked Immunosorbent Assay (ELISA) and serum estrogen level by RIA method in order to assess the hormonal level of both groups. Data was analyzed by Unpaired Student’s‘t’ test and Pearson's correlation co-effcient (r) test as applicable. Mean serum fasting insulin level and mean blood glucose level was higher in postmenopausal women than premenopausal and result was statistically significant. In postmenopausal women serum estrogen level was lower than premenopausal and serum estrogen level showed negative correlation with serum fasting insulin level. Blood glucose level also showed negative correlation with serum estrogen level. All these correlation were statistically non-significant. It may be concluded that the serum fasting insulin and blood glucose levels are significantly higher in postmenopausal women that may be due to low level of estrogen.Bangladesh Med J. 2017 Jan; 46 (1): 32-37
    Type of Medium: Online Resource
    ISSN: 2219-1607 , 0301-035X
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2017
    detail.hit.zdb_id: 2549257-3
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  • 10
    Online Resource
    Online Resource
    Scientific Research Publishing, Inc. ; 2020
    In:  Advances in Infectious Diseases Vol. 10, No. 03 ( 2020), p. 249-255
    In: Advances in Infectious Diseases, Scientific Research Publishing, Inc., Vol. 10, No. 03 ( 2020), p. 249-255
    Type of Medium: Online Resource
    ISSN: 2164-2648 , 2164-2656
    Language: Unknown
    Publisher: Scientific Research Publishing, Inc.
    Publication Date: 2020
    detail.hit.zdb_id: 2681304-X
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