In:
Journal of Surgical Oncology, Wiley, Vol. 113, No. 7 ( 2016-06), p. 775-778
Abstract:
There are limited adjuncts available for identifying and assessing the viability of parathyroid glands (PGs) during total thyroidectomy (TT). The aim of this study is to determine the feasibility of indocyanine green (ICG) imaging in identifying and assessing perfusion of PGs during TT. Methods ICG was administered in patients undergoing TT and fluorescence of PGs was assessed. A grading scale was developed for assessing degree of ICG uptake. Patients were evaluated for hypocalcemia and hypoparathyroidism on post‐operative day (POD) #1. Results Twenty‐seven patients underwent TT with ICG imaging for multinodular goiter (n = 13), thyroid cancer (n = 10), and Graves’ disease (n = 4). Eight‐five PGs were identified visually, 71 (84%) of which showed ICG fluorescence. False negative rate was 6%. Post‐operatively, three patients (11%) had a serum calcium value 〈 8 mg/dl. ICG uptake after TT correlated with post‐operative PTH levels: mean POD#1 PTH of those patients with at least two PGs exhibiting 〈 30% fluorescence was 9 pg/ml; whereas those with fewer than two demonstrating 〈 30% fluorescence had a POD#1 PTH of 19.5 pg/ml ( P = 0.05). Conclusion ICG imaging of PGs during TT is feasible. ICG might be a useful adjunct in identifying those patients at risk for post‐thyroidectomy hypoparathyroidism. J. Surg. Oncol. 2016;113:775–778 . © 2016 Wiley Periodicals, Inc.
Type of Medium:
Online Resource
ISSN:
0022-4790
,
1096-9098
Language:
English
Publisher:
Wiley
Publication Date:
2016
detail.hit.zdb_id:
1475314-5
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