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  • 1
    Online Resource
    Online Resource
    Fetal magnetic resonance imaging of lumbar spine development in vivo: a retrospective study
    Springer Science and Business Media LLC ; 2022
    In:  Child's Nervous System Vol. 38, No. 11 ( 2022-11), p. 2113-2118
    Details
    In: Child's Nervous System, Springer Science and Business Media LLC, Vol. 38, No. 11 ( 2022-11), p. 2113-2118
    Abstract: The aim of this study is to describe MR imaging appearances of the fetal lumbar spine in vivo at different gestational ages (GAs). Methods This retrospective study was approved by the Third Affiliated Hospital of Zhengzhou University. We collected MR images and clinical data of 93 fetuses in our hospital. All the MR images were obtained by 3-T MR. All had the mid-sagittal plane of steady state free precession sequence (Trufi) of the lumbar spine, which could show the lumbar vertebra and conus medullaris (CM). Regression analysis was made between GA and heights of lumbar vertebral body ossification center (LVBOC), lengths of LVBOC, and heights of intervertebral gap (IVG). Results There were good linear correlations between the heights of LVBOC and GA ( P   〈  0.001), lengths of LVBOC and GA ( P   〈  0.001), and heights of IVG and GA ( P   〈  0.001). Conclusion We showed the different development of each LVBOC and IVG which caused the difference of the shape of LVBOC and IVG.
    Type of Medium: Online Resource
    ISSN: 0256-7040 , 1433-0350
    URL: Article
    DOI: 10.1007/s00381-022-05645-x
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2022
    detail.hit.zdb_id: 1463024-2
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  • 2
    Online Resource
    Online Resource
    Improved Differential Diagnosis Based on BI-RADS Descriptors and Apparent Diffusion Coefficient for Breast Lesions: A Multiparametric MRI Analysis as Compared to Kaiser Score
    Elsevier BV ; 2023
    In:  Academic Radiology Vol. 30 ( 2023-09), p. S93-S103
    Details
    In: Academic Radiology, Elsevier BV, Vol. 30 ( 2023-09), p. S93-S103
    Type of Medium: Online Resource
    ISSN: 1076-6332
    URL: Article
    DOI: 10.1016/j.acra.2023.03.035
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2023
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  • 3
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    Hydroxysafflor yellow A increases BDNF and NMDARs in the hippocampus in a vascular dementia rat model
    Elsevier BV ; 2016
    In:  Brain Research Vol. 1642 ( 2016-07), p. 419-425
    Details
    In: Brain Research, Elsevier BV, Vol. 1642 ( 2016-07), p. 419-425
    Type of Medium: Online Resource
    ISSN: 0006-8993
    URL: Article
    DOI: 10.1016/j.brainres.2016.04.030
    RVK:
    XA 10000
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2016
    detail.hit.zdb_id: 1462674-3
    SSG: 12
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  • 4
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    Adsorption Characteristics of Dodecamethylcyclohexasiloxane and Dodecamethylpentasiloxane from Landfill Leachate by Municipal Solid Waste under the Landfill Circumstance
    MDPI AG ; 2022
    In:  Water Vol. 15, No. 1 ( 2022-12-28), p. 102-
    Details
    In: Water, MDPI AG, Vol. 15, No. 1 ( 2022-12-28), p. 102-
    Abstract: The release of siloxane from landfill leachate has attracted wide attention. In this study, dodecamethylcyclohexasiloxane (D6) and dodecamethylpentasiloxane (L5) were chosen as the target pollutants to investigate the adsorption characteristics of cyclosiloxane and linear siloxane on municipal solid waste (MSW) under the landfill circumstance. The adsorption behavior could be well described by the Langmuir–Freundlich model, with a maximum adsorption capacity of 0.677 μg g−1 and 15.864 μg g−1 for L5 and D6, respectively. It seems that D6 has a stronger affinity to MSW compared with L5. The maximum adsorption was observed when the pH was 5.0 and 5.5 for D6 and L5. The optical temperature was 30 °C. The organic acid and inorganic ions in the leachate could restrict the adsorption to a low level. The results suggested that the adsorption of siloxane on MSW could be limited at the methanogenic and mature stages, which may promote the distribution of siloxane in the leachate. The results could help to understand the release behavior of siloxane from landfill leachate during the running of a landfill.
    Type of Medium: Online Resource
    ISSN: 2073-4441
    URL: Article
    DOI: 10.3390/w15010102
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2521238-2
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  • 5
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    Online Resource
    Medial Temporal Lobe Atrophy is Related to Learning Strategy Changes in Amnestic Mild Cognitive Impairment
    Cambridge University Press (CUP) ; 2019
    In:  Journal of the International Neuropsychological Society Vol. 25, No. 7 ( 2019-08), p. 706-717
    Details
    In: Journal of the International Neuropsychological Society, Cambridge University Press (CUP), Vol. 25, No. 7 ( 2019-08), p. 706-717
    Abstract: Objective: Deficits in the semantic learning strategy were observed in subjects with amnestic mild cognitive impairment (aMCI) in our previous study. In the present study, we explored the contributions of executive function and brain structure changes to the decline in the semantic learning strategy in aMCI. Methods: A neuropsychological battery was used to test memory and executive function in 96 aMCI subjects and 90 age- and gender-matched healthy controls (HCs). The semantic clustering ratio on the verbal learning test was calculated to evaluate learning strategy. Medial temporal lobe atrophy (MTA) and white matter hyperintensities (WMH) were measured on MRI with the MTA and Fazekas visual rating scales, respectively. Results: Compared to HCs, aMCI subjects had poorer performance in terms of memory, executive function, and the semantic clustering ratio ( P 〈 .001). In aMCI subjects, no significant correlation between learning strategy and executive function was observed. aMCI subjects with obvious MTA demonstrated a lower semantic clustering ratio than those without MTA ( P 〈 .001). There was no significant difference in the learning strategies between subjects with high-grade WMH and subjects with low-grade WMH. Conclusion: aMCI subjects showed obvious impairment in the semantic learning strategy, which was attributable to MTA but independent of executive dysfunction and subcortical WMH. These findings need to be further validated in large cohorts with biomarkers identified using volumetric brain measurements. ( JINS , 2019, 25 , 706–717)
    Type of Medium: Online Resource
    ISSN: 1355-6177 , 1469-7661
    URL: Article
    DOI: 10.1017/S1355617719000353
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2019
    detail.hit.zdb_id: 2000018-2
    SSG: 5,2
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  • 6
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    Online Resource
    DataSheet_2.docx
    Frontiers Media SA ; 2021
    In:  Frontiers in Oncology Vol. 11 ( 2021-12-2)
    Details
    In: Frontiers in Oncology, Frontiers Media SA, Vol. 11 ( 2021-12-2)
    Abstract: To investigate the diagnostic performance of the Kaiser score and apparent diffusion coefficient (ADC) to differentiate Breast Imaging Reporting and Data System (BI-RADS) Category 4 lesions at dynamic contrast-enhanced (DCE) MRI. Methods This was a single-institution retrospective study of patients who underwent breast MRI from March 2020 to June 2021. All image data were acquired with a 3-T MRI system. Kaiser score of each lesion was assigned by an experienced breast radiologist. Kaiser score+ was determined by combining ADC and Kaiser score. Receiver operating characteristic (ROC) curve analysis was performed to evaluate the diagnostic performance of Kaiser score+, Kaiser score, and ADC. The area under the curve (AUC) values were calculated and compared by using the Delong test. The differences in sensitivity and specificity between different indicators were determined by the McNemar test. Results The study involved 243 women (mean age, 43.1 years; age range, 18–67 years) with 268 MR BI-RADS 4 lesions. Overall diagnostic performance for Kaiser score (AUC, 0.902) was significantly higher than for ADC (AUC, 0.81; p = 0.004). There were no significant differences in AUCs between Kaiser score and Kaiser score+ ( p = 0.134). The Kaiser score was superior to ADC in avoiding unnecessary biopsies ( p & lt; 0.001). Compared with the Kaiser score alone, the specificity of Kaiser score+ increased by 7.82%, however, at the price of a lower sensitivity. Conclusion For MR BI-RADS category 4 breast lesions, the Kaiser score was superior to ADC mapping regarding the potential to avoid unnecessary biopsies. However, the combination of both indicators did not significantly contribute to breast cancer diagnosis of this subgroup.
    Type of Medium: Online Resource
    ISSN: 2234-943X
    URL: Article
    URL: Article
    URL: Article
    DOI: 10.3389/fonc.2021.779642
    DOI: 10.3389/fonc.2021.779642.s001
    DOI: 10.3389/fonc.2021.779642.s002
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2021
    detail.hit.zdb_id: 2649216-7
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  • 7
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    Table_1.docx
    Frontiers Media SA ; 2022
    In:  Frontiers in Oncology Vol. 12 ( 2022-10-11)
    Details
    In: Frontiers in Oncology, Frontiers Media SA, Vol. 12 ( 2022-10-11)
    Abstract: To investigate whether there is added value of quantitative parameters from synthetic magnetic resonance imaging (SyMRI) as a complement to the Kaiser score (KS) to differentiate benign and malignant breast lesions. Materials and methods In this single-institution study, 122 patients who underwent breast MRI from March 2020 to May 2021 were retrospectively analyzed. SyMRI and dynamic contrast-enhanced MRI were performed using a 3.0-T system. Two experienced radiologists independently assigned the KS and measured the quantitative values of T1 relaxation time (T1), T2 relaxation time (T2), and proton density (PD) from SyMRI. Pathology was regarded as the gold standard. The diagnostic values were compared using the appropriate statistical tests. Results There were 122 lesions (86 malignant and 36 benign) in 122 women. The T1 value was identified as the only independent factor for the differentiation of malignant and benign lesions. The diagnostic accuracy of incorporating the T1 into the KS protocol (T1+KS) was 95.1% and 92.1% for all lesions (ALL) and The American College of Radiology (ACR) Breast Imaging Reporting and Data System (BI-RADS) category 4 lesions, respectively, which was significantly higher than that of either T1 (ALL: 82.8%, P = 0.0001; BI-RADS 4: 78.9%, P = 0.002) or KS (ALL: 90.2%, P = 0.031; BI-RADS 4: 84.2%, P = 0.031) alone. The sensitivity and specificity of T1+KS were also higher than those of the T1 or KS alone. The combined diagnosis could have avoided another 15.6% biopsies compared with using KS alone. Conclusions Incorporating T1 into the KS protocol improved both the sensitivity and specificity to differentiate benign and malignant breast lesions, thus avoiding unnecessary invasive procedures.
    Type of Medium: Online Resource
    ISSN: 2234-943X
    URL: Article
    URL: Article
    DOI: 10.3389/fonc.2022.964078
    DOI: 10.3389/fonc.2022.964078.s001
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2649216-7
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  • 8
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    Online Resource
    Semantic clustering and sleep in patients with amnestic mild cognitive impairment or with vascular cognitive impairment-no dementia
    Cambridge University Press (CUP) ; 2016
    In:  International Psychogeriatrics Vol. 28, No. 9 ( 2016-09), p. 1493-1502
    Details
    In: International Psychogeriatrics, Cambridge University Press (CUP), Vol. 28, No. 9 ( 2016-09), p. 1493-1502
    Abstract: Cognition and sleep deficits occur in amnestic mild cognitive impairment (aMCI) and vascular cognitive impairment-no dementia (VCIND). However, how memory and sleep deficits differ between aMCI and VCIND remains unclear. Methods: Fifty aMCI and 50 VCIND patients and 38 sex- and age-matched healthy controls (HCs) were administered the Hopkins Verbal Learning Test-Revised (HVLT-R), Trail Making Test-A/B (TMT-A/B), Wisconsin Card Sorting Test (WCST), Paced Auditory Serial Addition Test (PASAT), Symbol Digit Modalities Test (SDMT), Benton Judgment of Line Orientation (JLO) test, Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), and Insomnia Severity Index (ISI) to quantify cognitive deficits and subjective sleep disturbance. Results: Compared with VCIND patients, aMCI patients had lower HVLT-R scores for total recall ( p 〈 0.001), delayed recall ( p 〈 0.001) and recognition ( p = 0.001), and for total-recall ( p = 0.002) and delayed-recall ( p 〈 0.001) semantic clustering ratios (SCRs). However, VCIND patients exhibited more obvious executive dysfunction (TMT-A, p 〈 0.001; TMT-B, p 〈 0.001; WCST, p 〈 0.001), lower information processing speed (PASAT, p = 0.003; SDMT, p 〈 0.001), and more severe sleep disturbance (PSQI, p 〈 0.001; ESS, p 〈 0.001; ISI, p 〈 0.001). Additionally, sleep quality and efficiency were related to total and delayed recall (all r values from −0.31 to −0.60, p 〈 0.05) in aMCI and VCIND. Conclusions: aMCI and VCIND differ in cognitive function, memory strategy and sleep impairment; these characteristics are helpful to identify and distinguish patients with very early cognitive impairment. Our results also suggest that memory deficits are associated with sleep disturbance in aMCI and VCIND.
    Type of Medium: Online Resource
    ISSN: 1041-6102 , 1741-203X
    URL: Article
    DOI: 10.1017/S1041610216000739
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2016
    detail.hit.zdb_id: 2147136-8
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