In:
Journal of Computer Assisted Tomography, Ovid Technologies (Wolters Kluwer Health), Vol. 45, No. 1 ( 2021-1), p. 12-17
Abstract:
The purpose of this study was to evaluate the accuracy of quantifying hepatic fat fraction (HFF) in nonalcoholic fatty liver disease patients with multimaterial decomposition (MMD) and fat (water)-based material decomposition by single-source dual-energy computed tomography. Methods Hepatic fat fractions were quantified by noncontrast (HFF non-CE ) and contrast-enhanced single-source dual-energy computed tomography in arterial phase (HFF AP ), portal venous phase (HFF PVP ) and equilibrium phase (HFF EP ) using MMD in 19 nonalcoholic fatty liver disease patients. The fat concentration was measured on fat (water)-based images. As the standard of reference, magnetic resonance iterative decomposition of water and fat with echo asymmetry and least-squares estimation-iron quantification images were reconstructed to obtain HFF (HFF IDEAL-IQ ). Results There was a strong correlation between HFF non-CE , HFF AP , HFF PVP , HFF EP , fat concentration and HFF IDEAL-IQ ( r = 0.943, 0.923, 0.942, 0.952, and 0.726) with HFFs having better correlation with HFF IDEAL-IQ . Hepatic fat fractions did not significantly differ across scanning phases. The HFFs of 3-phase contrast-enhanced computed tomography had a good consistency with HFF non-CE . Conclusions Hepatic fat fraction using MMD has excellent correlation with that of magnetic resonance imaging, is independent of the computed tomography scanning phases, and may be used as a routine technique for quantitative assessment of HFF.
Type of Medium:
Online Resource
ISSN:
1532-3145
,
0363-8715
DOI:
10.1097/RCT.0000000000001112
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
2021
detail.hit.zdb_id:
2039772-0
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