In:
ECS Meeting Abstracts, The Electrochemical Society, Vol. MA2020-01, No. 28 ( 2020-05-01), p. 2185-2185
Abstract:
The highly sensitive detection of hydrogen peroxide (H 2 O 2 ) is of practical importance due to its involvement in the biofunction and signal transduction of cells. Various electrochemical techniques have been explored and studied for its detection, which can be realized through either enzymatic or non-enzymatic sensors. Particularly, non-enzymatic biosensors have been in great demand because of their high stability, high reproducibility, and less susceptible to environmental factors compared to the enzyme-based approach. However, many of them display inferior sensitivity or poor selectivity. Hence, this work aims to develop a highly sensitive non-enzymatic biosensor through structural and compositional approaches. From a structural point of view, Au inverse opals are utilized as the sensor scaffold due to their intriguing porous structure. The spatial arrangement of these materials resembles a honeycomb structure, which provides a high specific surface area, efficient mass transport, and strong mechanical stability. In addition to the benefits brought by inverse opals, we further incorporate a composite coating based on Cu 2 O to decorate the scaffold surface. Through the combination of a well-ordered pore structure with additional functionalization by composite formation, a synergistic improvement could be realized. To fabricate such structural biosensors, an expedited self-assembly process exploiting electrophoresis technique is first adopted to produce a colloidal crystal template. Subsequent electrodeposition processes are performed to construct the Au inverse opals and relevant functional coatings. The sensing performance of these 3D sensors is then evaluated by the detection of H 2 O 2 using cyclic voltammetric analysis. Their structural and compositional characterizations are conducted by SEM, EDX, XPS, and Raman spectroscopy.
Type of Medium:
Online Resource
ISSN:
2151-2043
DOI:
10.1149/MA2020-01282185mtgabs
Language:
Unknown
Publisher:
The Electrochemical Society
Publication Date:
2020
detail.hit.zdb_id:
2438749-6
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