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  • 1
    Online Resource
    Online Resource
    Springer Science and Business Media LLC ; 2015
    In:  Frontiers of Computer Science Vol. 9, No. 3 ( 2015-6), p. 474-484
    In: Frontiers of Computer Science, Springer Science and Business Media LLC, Vol. 9, No. 3 ( 2015-6), p. 474-484
    Type of Medium: Online Resource
    ISSN: 2095-2228 , 2095-2236
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2015
    detail.hit.zdb_id: 2658960-6
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  • 2
    Online Resource
    Online Resource
    Springer Science and Business Media LLC ; 2011
    In:  International Journal of Computational Intelligence Systems Vol. 4, No. 5 ( 2011), p. 977-
    In: International Journal of Computational Intelligence Systems, Springer Science and Business Media LLC, Vol. 4, No. 5 ( 2011), p. 977-
    Type of Medium: Online Resource
    ISSN: 1875-6883
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2011
    detail.hit.zdb_id: 2754752-8
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  • 3
    In: Disease Markers, Hindawi Limited, Vol. 2021 ( 2021-7-29), p. 1-8
    Abstract: Aims. The lack of primary ophthalmologists in China results in the inability of basic-level hospitals to diagnose pterygium patients. To solve this problem, an intelligent-assisted lightweight pterygium diagnosis model based on anterior segment images is proposed in this study. Methods. Pterygium is a common and frequently occurring disease in ophthalmology, and fibrous tissue hyperplasia is both a diagnostic biomarker and a surgical biomarker. The model diagnosed pterygium based on biomarkers of pterygium. First, a total of 436 anterior segment images were collected; then, two intelligent-assisted lightweight pterygium diagnosis models (MobileNet 1 and MobileNet 2) based on raw data and augmented data were trained via transfer learning. The results of the lightweight models were compared with the clinical results. The classic models (AlexNet, VGG16 and ResNet18) were also used for training and testing, and their results were compared with the lightweight models. A total of 188 anterior segment images were used for testing. Sensitivity, specificity, F1-score, accuracy, kappa, area under the concentration-time curve (AUC), 95% CI, size, and parameters are the evaluation indicators in this study. Results. There are 188 anterior segment images that were used for testing the five intelligent-assisted pterygium diagnosis models. The overall evaluation index for the MobileNet2 model was the best. The sensitivity, specificity, F1-score, and AUC of the MobileNet2 model for the normal anterior segment image diagnosis were 96.72%, 98.43%, 96.72%, and 0976, respectively; for the pterygium observation period anterior segment image diagnosis, the sensitivity, specificity, F1-score, and AUC were 83.7%, 90.48%, 82.54%, and 0.872, respectively; for the surgery period anterior segment image diagnosis, the sensitivity, specificity, F1-score, and AUC were 84.62%, 93.50%, 85.94%, and 0.891, respectively. The kappa value of the MobileNet2 model was 77.64%, the accuracy was 85.11%, the model size was 13.5 M, and the parameter size was 4.2 M. Conclusion. This study used deep learning methods to propose a three-category intelligent lightweight-assisted pterygium diagnosis model. The developed model can be used to screen patients for pterygium problems initially, provide reasonable suggestions, and provide timely referrals. It can help primary doctors improve pterygium diagnoses, confer social benefits, and lay the foundation for future models to be embedded in mobile devices.
    Type of Medium: Online Resource
    ISSN: 1875-8630 , 0278-0240
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2021
    detail.hit.zdb_id: 2033253-1
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  • 4
    Online Resource
    Online Resource
    Elsevier BV ; 2010
    In:  Knowledge-Based Systems Vol. 23, No. 1 ( 2010-2), p. 70-76
    In: Knowledge-Based Systems, Elsevier BV, Vol. 23, No. 1 ( 2010-2), p. 70-76
    Type of Medium: Online Resource
    ISSN: 0950-7051
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2010
    detail.hit.zdb_id: 2017495-0
    SSG: 24,1
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  • 5
    In: PLoS ONE, Public Library of Science (PLoS), Vol. 7, No. 9 ( 2012-9-19), p. e45464-
    Type of Medium: Online Resource
    ISSN: 1932-6203
    Language: English
    Publisher: Public Library of Science (PLoS)
    Publication Date: 2012
    detail.hit.zdb_id: 2267670-3
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  • 6
    Online Resource
    Online Resource
    Frontiers Media SA ; 2022
    In:  Frontiers in Computational Neuroscience Vol. 16 ( 2022-12-8)
    In: Frontiers in Computational Neuroscience, Frontiers Media SA, Vol. 16 ( 2022-12-8)
    Abstract: To assess the value of an automated classification model for dry and wet macular degeneration based on the ConvNeXT model. Methods A total of 672 fundus images of normal, dry, and wet macular degeneration were collected from the Affiliated Eye Hospital of Nanjing Medical University and the fundus images of dry macular degeneration were expanded. The ConvNeXT three-category model was trained on the original and expanded datasets, and compared to the results of the VGG16, ResNet18, ResNet50, EfficientNetB7, and RegNet three-category models. A total of 289 fundus images were used to test the models, and the classification results of the models on different datasets were compared. The main evaluation indicators were sensitivity, specificity, F1-score, area under the curve (AUC), accuracy, and kappa. Results Using 289 fundus images, three-category models trained on the original and expanded datasets were assessed. The ConvNeXT model trained on the expanded dataset was the most effective, with a diagnostic accuracy of 96.89%, kappa value of 94.99%, and high diagnostic consistency. The sensitivity, specificity, F1-score, and AUC values for normal fundus images were 100.00, 99.41, 99.59, and 99.80%, respectively. The sensitivity, specificity, F1-score, and AUC values for dry macular degeneration diagnosis were 87.50, 98.76, 90.32, and 97.10%, respectively. The sensitivity, specificity, F1-score, and AUC values for wet macular degeneration diagnosis were 97.52, 97.02, 96.72, and 99.10%, respectively. Conclusion The ConvNeXT-based category model for dry and wet macular degeneration automatically identified dry and wet macular degeneration, aiding rapid, and accurate clinical diagnosis.
    Type of Medium: Online Resource
    ISSN: 1662-5188
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2452964-3
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  • 7
    In: Frontiers in Neurology, Frontiers Media SA, Vol. 13 ( 2022-7-27)
    Abstract: To assess the value of automatic disc-fovea angle (DFA) measurement using the DeepLabv3+ segmentation model. Methods A total of 682 normal fundus image datasets were collected from the Eye Hospital of Nanjing Medical University. The following parts of the images were labeled and subsequently reviewed by ophthalmologists: optic disc center, macular center, optic disc area, and virtual macular area. A total of 477 normal fundus images were used to train DeepLabv3+, U-Net, and PSPNet model, which were used to obtain the optic disc area and virtual macular area. Then, the coordinates of the optic disc center and macular center were obstained by using the minimum outer circle technique. Finally the DFA was calculated. Results In this study, 205 normal fundus images were used to test the model. The experimental results showed that the errors in automatic DFA measurement using DeepLabv3+, U-Net, and PSPNet segmentation models were 0.76°, 1.4°, and 2.12°, respectively. The mean intersection over union (MIoU), mean pixel accuracy (MPA), average error in the center of the optic disc, and average error in the center of the virtual macula obstained by using DeepLabv3+ model was 94.77%, 97.32%, 10.94 pixels, and 13.44 pixels, respectively. The automatic DFA measurement using DeepLabv3+ got the less error than the errors that using the other segmentation models. Therefore, the DeepLabv3+ segmentation model was finally chosen to measure DFA automatically. Conclusions The DeepLabv3+ segmentation model -based automatic segmentation techniques can produce accurate and rapid DFA measurements.
    Type of Medium: Online Resource
    ISSN: 1664-2295
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2564214-5
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  • 8
    Online Resource
    Online Resource
    IGI Global ; 2021
    In:  International Journal of Information Technology and Web Engineering Vol. 16, No. 2 ( 2021-4-1), p. 58-74
    In: International Journal of Information Technology and Web Engineering, IGI Global, Vol. 16, No. 2 ( 2021-4-1), p. 58-74
    Type of Medium: Online Resource
    ISSN: 1554-1045 , 1554-1053
    URL: Issue
    URL: Issue
    Language: Ndonga
    Publisher: IGI Global
    Publication Date: 2021
    detail.hit.zdb_id: 2400989-1
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  • 9
    In: Frontiers in Medicine, Frontiers Media SA, Vol. 9 ( 2022-2-23)
    Abstract: A six-category model of common retinal diseases is proposed to help primary medical institutions in the preliminary screening of the five common retinal diseases. Methods A total of 2,400 fundus images of normal and five common retinal diseases were provided by a cooperative hospital. Two six-category deep learning models of common retinal diseases based on the EfficientNet-B4 and ResNet50 models were trained. The results from the six-category models in this study and the results from a five-category model in our previous study based on ResNet50 were compared. A total of 1,315 fundus images were used to test the models, the clinical diagnosis results and the diagnosis results of the two six-category models were compared. The main evaluation indicators were sensitivity, specificity, F1-score, area under the curve (AUC), 95% confidence interval, kappa and accuracy, and the receiver operator characteristic curves of the two six-category models were compared in the study. Results The diagnostic accuracy rate of EfficientNet-B4 model was 95.59%, the kappa value was 94.61%, and there was high diagnostic consistency. The AUC of the normal diagnosis and the five retinal diseases were all above 0.95. The sensitivity, specificity, and F1-score for the diagnosis of normal fundus images were 100, 99.9, and 99.83%, respectively. The specificity and F1-score for RVO diagnosis were 95.68, 98.61, and 93.09%, respectively. The sensitivity, specificity, and F1-score for high myopia diagnosis were 96.1, 99.6, and 97.37%, respectively. The sensitivity, specificity, and F1-score for glaucoma diagnosis were 97.62, 99.07, and 94.62%, respectively. The sensitivity, specificity, and F1-score for DR diagnosis were 90.76, 99.16, and 93.3%, respectively. The sensitivity, specificity, and F1-score for MD diagnosis were 92.27, 98.5, and 91.51%, respectively. Conclusion The EfficientNet-B4 model was used to design a six-category model of common retinal diseases. It can be used to diagnose the normal fundus and five common retinal diseases based on fundus images. It can help primary doctors in the screening for common retinal diseases, and give suitable suggestions and recommendations. Timely referral can improve the efficiency of diagnosis of eye diseases in rural areas and avoid delaying treatment.
    Type of Medium: Online Resource
    ISSN: 2296-858X
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2775999-4
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  • 10
    Online Resource
    Online Resource
    Hindawi Limited ; 2022
    In:  Journal of Healthcare Engineering Vol. 2022 ( 2022-11-21), p. 1-9
    In: Journal of Healthcare Engineering, Hindawi Limited, Vol. 2022 ( 2022-11-21), p. 1-9
    Abstract: A two-category model and a segmentation model of pterygium were proposed to assist ophthalmologists in establishing the diagnosis of ophthalmic diseases. A total of 367 normal anterior segment images and 367 pterygium anterior segment images were collected at the Affiliated Eye Hospital of Nanjing Medical University. AlexNet, VGG16, ResNet18, and ResNet50 models were used to train the two-category pterygium models. A total of 150 normal and 150 pterygium anterior segment images were used to test the models, and the results were compared. The main evaluation indicators, including sensitivity, specificity, area under the curve, kappa value, and receiver operator characteristic curves of the four models, were compared. Simultaneously, 367 pterygium anterior segment images were used to train two improved pterygium segmentation models based on PSPNet. A total of 150 pterygium images were used to test the models, and the results were compared with those of the other four segmentation models. The main evaluation indicators included mean intersection over union (MIOU), IOU, mean average precision (MPA), and PA. Among the two-category models of pterygium, the best diagnostic result was obtained using the VGG16 model. The diagnostic accuracy, kappa value, diagnostic sensitivity of pterygium, diagnostic specificity of pterygium, and F1-score were 99%, 98%, 98.67%, 99.33%, and 99%, respectively. Among the pterygium segmentation models, the double phase-fusion PSPNet model had the best results, with MIOU, IOU, MPA, and PA of 86.57%, 78.1%, 92.3%, and 86.96%, respectively. This study designed a pterygium two-category model and a pterygium segmentation model for the images of the normal anterior and pterygium anterior segments, which could help patients self-screen easily and assist ophthalmologists in establishing the diagnosis of ophthalmic diseases and marking the actual scope of surgery.
    Type of Medium: Online Resource
    ISSN: 2040-2309 , 2040-2295
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2022
    detail.hit.zdb_id: 2545054-2
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