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  • 1
    Online Resource
    Online Resource
    American Society for Cell Biology (ASCB) ; 2018
    In:  CBE—Life Sciences Education Vol. 17, No. 1 ( 2018-03), p. ar6-
    In: CBE—Life Sciences Education, American Society for Cell Biology (ASCB), Vol. 17, No. 1 ( 2018-03), p. ar6-
    Abstract: In this article, we begin to unpack the phenomenon of representational competence by exploring how arrow symbols are used in introductory biology textbook figures. Out of 1214 figures in an introductory biology textbook, 632 (52%) of them contained arrows that were used to represent many different concepts or processes. Analysis of these figures revealed little correlation between arrow style and meaning. A more focused study of 86 figures containing 230 arrows from a second textbook showed the same pattern of inconsistency. Interviews with undergraduates confirmed that arrows in selected textbook figures were confusing and did not readily convey the information intended by the authors. We also present findings from an online survey in which subjects were asked to infer meaning of different styles of arrows in the absence of context. Few arrow styles had intrinsic meaning to participants, and illustrators did not always use those arrows for the meanings expected by students. Thus, certain styles of arrows triggered confusion and/or incorrect conceptual ideas. We argue that 1) illustrators need to be more clear and consistent when using arrow symbols, 2) instructors need to be cognizant of the level of clarity of representations used during instruction, and 3) instructors should help students learn how to interpret representations containing arrows.
    Type of Medium: Online Resource
    ISSN: 1931-7913
    Language: English
    Publisher: American Society for Cell Biology (ASCB)
    Publication Date: 2018
    detail.hit.zdb_id: 2465176-X
    SSG: 5,3
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  • 2
    Online Resource
    Online Resource
    American Society for Cell Biology (ASCB) ; 2016
    In:  CBE—Life Sciences Education Vol. 15, No. 2 ( 2016-06), p. ar9-
    In: CBE—Life Sciences Education, American Society for Cell Biology (ASCB), Vol. 15, No. 2 ( 2016-06), p. ar9-
    Abstract: Scientific teaching requires scientifically constructed, field-tested instruments to accurately evaluate student thinking and gauge teacher effectiveness. We have developed a 23-question, multiple select–format assessment of student understanding of the essential concepts of the central dogma of molecular biology that is appropriate for all levels of undergraduate biology. Questions for the Central Dogma Concept Inventory (CDCI) tool were developed and iteratively revised based on student language and review by experts. The ability of the CDCI to discriminate between levels of understanding of the central dogma is supported by field testing (N = 54), and large-scale beta testing (N = 1733). Performance on the assessment increased with experience in biology; scores covered a broad range and showed no ceiling effect, even with senior biology majors, and pre/posttesting of a single class focused on the central dogma showed significant improvement. The multiple-select format reduces the chances of correct answers by random guessing, allows students at different levels to exhibit the extent of their knowledge, and provides deeper insight into the complexity of student thinking on each theme. To date, the CDCI is the first tool dedicated to measuring student thinking about the central dogma of molecular biology, and version 5 is ready to use.
    Type of Medium: Online Resource
    ISSN: 1931-7913
    Language: English
    Publisher: American Society for Cell Biology (ASCB)
    Publication Date: 2016
    detail.hit.zdb_id: 2465176-X
    SSG: 5,3
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  • 3
    Online Resource
    Online Resource
    American Society for Cell Biology (ASCB) ; 2012
    In:  CBE—Life Sciences Education Vol. 11, No. 4 ( 2012-12), p. 425-436
    In: CBE—Life Sciences Education, American Society for Cell Biology (ASCB), Vol. 11, No. 4 ( 2012-12), p. 425-436
    Abstract: Cellular processes that rely on knowledge of molecular behavior are difficult for students to comprehend. For example, thorough understanding of meiosis requires students to integrate several complex concepts related to chromosome structure and function. Using a grounded theory approach, we have unified classroom observations, assessment data, and in-depth interviews under the theory of knowledge transfer to explain student difficulties with concepts related to chromosomal behavior. In this paper, we show that students typically understand basic chromosome structure but do not activate cognitive resources that would allow them to explain macromolecular phenomena (e.g., homologous pairing during meiosis). To improve understanding of topics related to genetic information flow, we suggest that instructors use pedagogies and activities that prime students for making connections between chromosome structure and cellular processes.
    Type of Medium: Online Resource
    ISSN: 1931-7913
    Language: English
    Publisher: American Society for Cell Biology (ASCB)
    Publication Date: 2012
    detail.hit.zdb_id: 2465176-X
    SSG: 5,3
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  • 4
    Online Resource
    Online Resource
    American Society for Cell Biology (ASCB) ; 2022
    In:  CBE—Life Sciences Education Vol. 21, No. 3 ( 2022-09)
    In: CBE—Life Sciences Education, American Society for Cell Biology (ASCB), Vol. 21, No. 3 ( 2022-09)
    Abstract: Learning molecular biology involves using visual representations to communicate ideas about largely unobservable biological processes and molecules. Genes and gene expression cannot be directly visualized, but students are expected to learn and understand these and related concepts. Theoretically, textbook illustrations should help learners master such concepts, but how are genes and other DNA-linked concepts illustrated for learners? We examined all DNA-related images found in 12 undergraduate biology textbooks to better understand what biology students encounter when learning concepts related to DNA. Our analysis revealed a wide array of DNA images that were used to design a new visual framework, the DNA Landscape, which we applied to more than 2000 images from common introductory and advanced biology textbooks. All DNA illustrations could be placed on the landscape framework, but certain positions were more common than others. We mapped figures about “gene expression” and “meiosis” onto the landscape framework to explore how these challenging topics are illustrated for learners, aligning these outcomes with the research literature to showcase how the overuse of certain representations may hinder, instead of help, learning. The DNA Landscape is a tool to promote research on visual literacy and to guide new learning activities for molecular biology.
    Type of Medium: Online Resource
    ISSN: 1931-7913
    Language: English
    Publisher: American Society for Cell Biology (ASCB)
    Publication Date: 2022
    detail.hit.zdb_id: 2465176-X
    SSG: 5,3
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  • 5
    Online Resource
    Online Resource
    University of California Press ; 2020
    In:  The American Biology Teacher Vol. 82, No. 5 ( 2020-05-01), p. 296-305
    In: The American Biology Teacher, University of California Press, Vol. 82, No. 5 ( 2020-05-01), p. 296-305
    Abstract: The process of meiosis is an essential topic that secondary and postsecondary students struggle with. The important meiosis-related concepts of homology, ploidy, and segregation can be described using the DNA Triangle framework, which connects them to the multidimensional nature of DNA (chromosomal, molecular, and informational levels). We have previously established that undergraduate biology students typically fail to describe and/or link appropriate levels to their explanations of meiosis. We hypothesize that students' understanding mirrors the resources they are given – in other words, textbook figures often lack many of the important connections that experts include when talking about meiosis. Prior work showed that text in meiosis chapters typically fails to include many concepts that experts consider important, so we examined how textbook figures present meiosis concepts. We found that almost all textbook representations include the chromosomal level of DNA, but few include the other levels, even to illustrate concepts that are rooted in informational and/or molecular levels. In particular, the molecular level of DNA was absent from nearly all introductory textbook figures examined, and the informational level was seldom depicted in mid/upper-level textbook figures. The previously established deficits in text portions of textbooks are clearly not compensated by their accompanying illustrations.
    Type of Medium: Online Resource
    ISSN: 0002-7685 , 1938-4211
    Language: English
    Publisher: University of California Press
    Publication Date: 2020
    detail.hit.zdb_id: 412886-2
    detail.hit.zdb_id: 2065785-7
    SSG: 12
    SSG: 5,3
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  • 6
    Online Resource
    Online Resource
    CourseSource ; 2020
    In:  CourseSource Vol. 7 ( 2020)
    In: CourseSource, CourseSource, Vol. 7 ( 2020)
    Type of Medium: Online Resource
    ISSN: 2332-6530
    Language: Unknown
    Publisher: CourseSource
    Publication Date: 2020
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  • 7
    Online Resource
    Online Resource
    Wiley ; 2011
    In:  Biochemistry and Molecular Biology Education Vol. 39, No. 5 ( 2011-09), p. 344-351
    In: Biochemistry and Molecular Biology Education, Wiley, Vol. 39, No. 5 ( 2011-09), p. 344-351
    Type of Medium: Online Resource
    ISSN: 1470-8175
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2011
    detail.hit.zdb_id: 2039717-3
    SSG: 12
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  • 8
    Online Resource
    Online Resource
    Wiley ; 2018
    In:  Biochemistry and Molecular Biology Education Vol. 46, No. 5 ( 2018-09), p. 435-444
    In: Biochemistry and Molecular Biology Education, Wiley, Vol. 46, No. 5 ( 2018-09), p. 435-444
    Abstract: The essence of molecular biology education lies in understanding of gene expression, with subtopics including the central dogma processes, such as transcription and translation. While these concepts are core to the discipline, they are also notoriously difficult for students to learn, probably because they cannot be directly observed. While nearly all active learning strategies have been shown to improve learning compared with passive lectures, little has been done to compare different types of active learning. We hypothesized that physical models of central dogma processes would be especially helpful for learning, because they provide a resource that students can see, touch, and manipulate while trying to build their knowledge. For students enrolled in an entirely active‐learning‐based Cell & Molecular Biology course, we examined whether model‐based activities were more effective than non‐model based activities. To test their understanding at the beginning and end of the semester, we employed the multiple‐select Central Dogma Concept Inventory (CDCI). Each student acted as their own control, as all students engaged in all lessons yet some questions related to model‐based activities and some related to clicker questions, group problem‐solving, and other non‐model‐based activities. While all students demonstrated learning gains on both types of question, they showed much higher learning gains on model‐based questions. Examining their selected answers in detail showed that while higher performing students were prompted to refine their already‐good mental models to be even better, lower performing students were able to construct new knowledge that was much more consistent with an expert's understanding. © 2018 The Authors. Biochemistry and Molecular Biology Education published by Wiley Periodicals, Inc. on behalf of International Union of Biochemistry and Molecular Biology., 46(5):435–444, 2018.
    Type of Medium: Online Resource
    ISSN: 1470-8175 , 1539-3429
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2018
    detail.hit.zdb_id: 2039717-3
    SSG: 12
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  • 9
    Online Resource
    Online Resource
    American Society for Microbiology ; 2020
    In:  Journal of Microbiology & Biology Education Vol. 21, No. 2 ( 2020-01)
    In: Journal of Microbiology & Biology Education, American Society for Microbiology, Vol. 21, No. 2 ( 2020-01)
    Abstract: Topics related to energy transformation and metabolism are important parts of an undergraduate biology curriculum, but these are also topics that students traditionally struggle with. To address this, we have created a short online Interactive Video Vignette (IVV) called To Ferment or Not to Ferment: That is the Question . This IVV is designed to help students learn important ideas related to cellular respiration and metabolism. Students in various courses across four institutions were assigned the IVV as an out-of-class preinstruction homework assignment. To test the effectiveness of this IVV on student learning, we collected and analyzed data from questions embedded in the IVV, open response reflection questions, and pre- and postassessments from IVV watchers and nonwatchers. Our analysis revealed that students who completed the IVV activity interacted productively with this online tool and made significant learning gains on important topics related to cellular respiration and metabolism. This IVV is freely available via https://www.rit.edu/cos/interactive/MINT for instructors to adopt for class use.
    Type of Medium: Online Resource
    ISSN: 1935-7877 , 1935-7885
    Language: English
    Publisher: American Society for Microbiology
    Publication Date: 2020
    detail.hit.zdb_id: 2560245-7
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  • 10
    Online Resource
    Online Resource
    American Society for Cell Biology (ASCB) ; 2021
    In:  CBE—Life Sciences Education Vol. 20, No. 4 ( 2021-12)
    In: CBE—Life Sciences Education, American Society for Cell Biology (ASCB), Vol. 20, No. 4 ( 2021-12)
    Abstract: Concepts of molecular biology and genetics are difficult for many biology undergraduate students to master yet are crucial for deep understanding of how life works. By asking students to draw their ideas, we attempted to uncover the mental models about genes and gene expression held by biology students ( n = 23) and experts ( n = 18) using semistructured interviews. A large divide was identified between novice and expert conceptions. While experts typically drew box-and-line representations and thought about genes as regions of DNA that were used to encode products, students typically drew whole chromosomes rather than focusing on gene structure and conflated gene expression with simple phenotypic outcomes. Experts universally described gene expression as a set of molecular processes involving transcription and translation, whereas students often associated gene expression with Punnett squares and phenotypic outcomes. Follow-up survey data containing a ranking question confirmed students’ alignment of their mental models with the images uncovered during interviews ( n = 156 undergraduate biology students) and indicated that Advanced students demonstrate a shift toward expert-like thinking. An analysis of 14 commonly used biology textbooks did not show any relationship between Punnett squares and discussions of gene expression, so it is doubtful students’ ideas originate directly from textbook reading assignments. Our findings add to the literature about mechanistic reasoning abilities of learners and provide new insights into how biology students think about genes and gene expression.
    Type of Medium: Online Resource
    ISSN: 1931-7913
    Language: English
    Publisher: American Society for Cell Biology (ASCB)
    Publication Date: 2021
    detail.hit.zdb_id: 2465176-X
    SSG: 5,3
    Location Call Number Limitation Availability
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