In:
PLOS Neglected Tropical Diseases, Public Library of Science (PLoS), Vol. 18, No. 3 ( 2024-3-14), p. e0012022-
Abstract:
Pacific Island countries have experienced periodic dengue, chikungunya and Zika outbreaks for decades. The prevention and control of these mosquito-borne diseases rely heavily on control of Aedes aegypti mosquitoes, which in most settings are the primary vector. Introgression of the intracellular bacterium Wolbachia pipientis ( w Mel strain) into Ae . aegypti populations reduces their vector competence and consequently lowers dengue incidence in the human population. Here we describe successful area-wide deployments of w Mel-infected Ae . aegypti in Suva, Lautoka, Nadi (Fiji), Port Vila (Vanuatu) and South Tarawa (Kiribati). With community support, weekly releases of w Mel-infected Ae . aegypti mosquitoes for between 2 to 5 months resulted in w Mel introgression in nearly all locations. Long term monitoring confirmed a high, self-sustaining prevalence of w Mel infecting mosquitoes in almost all deployment areas. Measurement of public health outcomes were disrupted by the Covid19 pandemic but are expected to emerge in the coming years.
Type of Medium:
Online Resource
ISSN:
1935-2735
DOI:
10.1371/journal.pntd.0012022
DOI:
10.1371/journal.pntd.0012022.g001
DOI:
10.1371/journal.pntd.0012022.g002
DOI:
10.1371/journal.pntd.0012022.g003
DOI:
10.1371/journal.pntd.0012022.g004
DOI:
10.1371/journal.pntd.0012022.g005
DOI:
10.1371/journal.pntd.0012022.g006
DOI:
10.1371/journal.pntd.0012022.g007
DOI:
10.1371/journal.pntd.0012022.g008
DOI:
10.1371/journal.pntd.0012022.t001
DOI:
10.1371/journal.pntd.0012022.t002
DOI:
10.1371/journal.pntd.0012022.s001
DOI:
10.1371/journal.pntd.0012022.s002
DOI:
10.1371/journal.pntd.0012022.s003
DOI:
10.1371/journal.pntd.0012022.s004
DOI:
10.1371/journal.pntd.0012022.s005
DOI:
10.1371/journal.pntd.0012022.s006
DOI:
10.1371/journal.pntd.0012022.s007
DOI:
10.1371/journal.pntd.0012022.s008
DOI:
10.1371/journal.pntd.0012022.s009
DOI:
10.1371/journal.pntd.0012022.s010
DOI:
10.1371/journal.pntd.0012022.s011
DOI:
10.1371/journal.pntd.0012022.s012
DOI:
10.1371/journal.pntd.0012022.r001
DOI:
10.1371/journal.pntd.0012022.r002
DOI:
10.1371/journal.pntd.0012022.r003
DOI:
10.1371/journal.pntd.0012022.r004
Language:
English
Publisher:
Public Library of Science (PLoS)
Publication Date:
2024
detail.hit.zdb_id:
2429704-5
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