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  • 1
    Online Resource
    Online Resource
    Atlantic salmon in regulated rivers: Understanding river management through the ecosystem services lens
    Wiley ; 2022
    In:  Fish and Fisheries Vol. 23, No. 2 ( 2022-03), p. 478-491
    Details
    In: Fish and Fisheries, Wiley, Vol. 23, No. 2 ( 2022-03), p. 478-491
    Abstract: Known as the “king of fishes,” the Atlantic salmon ( Salmo salar , Salmonidae) is an iconic freshwater species whose contribution to human well‐being has long been recognized, as have widespread declines in its abundance, partly due to river regulation. To understand how salmon conservation has been addressed within the ecosystem services (ES) framework, we synthesized the peer‐reviewed literature on ES provided by salmon in regulated rivers. We developed a search string to capture allusions to provisioning, regulating, supporting and cultural ES and assessed the results to identify knowledge gaps. The effects of hydropower on fisheries catches and on modelled populations were shown in several publications. Overall, few studies focused explicitly on ES from salmon and hydropower; this is surprising given the considerable body of literature on salmon in regulated rivers. Wild salmon as a food source and other provisioning services are less important today than historically. Because predators such as salmon are important for facilitating biodiversity by cycling nutrients and controlling food webs, there is a scope of work for future assessments of these regulating and supporting services. Few papers explicitly addressed cultural ES, despite the salmon's longstanding iconic status; this is a knowledge gap for future ES assessments in relation to hydropower. The influence of ES assessments for policy makers is growing through the Intergovernmental Panel for Biodiversity and Ecosystem Services (IPBES) and the post‐2020 biodiversity strategy. Explicitly addressing ES poses an opportunity for river managers to raise awareness of aquatic conservation efforts and well‐informed decision‐making for sustaining ES.
    Type of Medium: Online Resource
    ISSN: 1467-2960 , 1467-2979
    URL: Issue
    URL: Article
    DOI: 10.1111/faf.v23.2
    DOI: 10.1111/faf.12628
    Language: English
    Publisher: Wiley
    Publication Date: 2022
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  • 2
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    The role of temperature in the prey capture probability of drift-feeding juvenile brown trout (Salmo trutta) : Temperature effects on the prey capture probability of brown trout
    Wiley ; 2011
    In:  Ecology of Freshwater Fish Vol. 20, No. 3 ( 2011-09), p. 393-399
    Details
    In: Ecology of Freshwater Fish, Wiley, Vol. 20, No. 3 ( 2011-09), p. 393-399
    Type of Medium: Online Resource
    ISSN: 0906-6691
    URL: Issue
    URL: Article
    DOI: 10.1111/eff.2011.20.issue-3
    DOI: 10.1111/j.1600-0633.2010.00470.x
    Language: English
    Publisher: Wiley
    Publication Date: 2011
    detail.hit.zdb_id: 2028166-3
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  • 3
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    Growth and mortality of sympatric Atlantic salmon and brown trout fry in fluctuating and stable flows
    Wiley ; 2023
    In:  Ecology of Freshwater Fish Vol. 32, No. 2 ( 2023-04), p. 282-290
    Details
    In: Ecology of Freshwater Fish, Wiley, Vol. 32, No. 2 ( 2023-04), p. 282-290
    Abstract: Sub‐daily fluctuations in streamflow may have adverse effects on the biota downstream of dams in hydropeaking‐regulated rivers. Although the stranding of salmonid fry is one documented effect of hydropeaking, little is known about the species‐specific behavioural and subsequent growth effects of sub‐daily flow fluctuations. We investigated the effects of sub‐daily flow fluctuation on growth, mortality and behaviour of sympatric Atlantic salmon ( Salmo salar ) and brown trout ( S. trutta ) fry (29–34 mm) in a laboratory experiment. The fluctuating flow treatment negatively affected growth and increased mortality for trout but not for salmon. The level of aggressive behaviour was similar in the fluctuating‐ and stable‐flow treatments. Within the fluctuating flow treatment, there was a trend that more fishes were visibly active above the substrate during low than high flow. These findings suggest that hydropeaking‐induced flow fluctuations may affect fry of different salmonid species in different ways and that brown trout fry may be more vulnerable to hydropeaking effects than Atlantic salmon fry. It can therefore be important to consider the possibility of divergent reactions by different fish species under hydropeaking situations and to incorporate species‐specific strategies to conserve culturally and economically relevant riverine fish species.
    Type of Medium: Online Resource
    ISSN: 0906-6691 , 1600-0633
    URL: Issue
    URL: Article
    DOI: 10.1111/eff.v32.2
    DOI: 10.1111/eff.12685
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2028166-3
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  • 4
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    Social behaviour of European grayling before and after flow peaks in restored and unrestored habitats
    Wiley ; 2020
    In:  River Research and Applications Vol. 36, No. 8 ( 2020-10), p. 1646-1655
    Details
    In: River Research and Applications, Wiley, Vol. 36, No. 8 ( 2020-10), p. 1646-1655
    Abstract: Cost‐effective implementation of fish‐friendly hydropower flow operation and habitat restoration measures require an understanding of their effects on fitness‐related behaviours of stream fish. Here, we investigated how changes in flow and bottom structure influence the social behaviour of European grayling, using large experimental flumes (700 L s −1 ), with and without added boulders (i.e., restored and unrestored habitat). Grayling increased their distance to nearest neighbour at the start of flow ramping up and after a flow peak compared to stable base flow. At the start of ramping up the flow, grayling made less position changes (movements 〉 1 m) than at stable base flow and after a flow peak. In the unrestored habitat, the proportion of time grayling spent actively swimming was lower before a flow peak than it was both at the start of ramping up the flow and after the peak, an effect not found in the restored habitat. In addition, we compared two static flows, and habitat restoration mediated their effect on distance to nearest neighbour. Grayling in the restored habitat were positioned closer to each other in the low (~10 cm s −1 ) than in the intermediate static flow (~40 cm s −1 ), whereas in the unrestored habitat, grayling showed the opposite pattern. Moreover, grayling reduced their number of position changes in the intermediate static flow, which was reflected by a reduction in active swimming. Stomach analysis after the trials revealed that foraging success was higher in variable than in the stable flow treatment. These results show that flow magnitude, flow changes and instream structure play important roles in the behaviour of stream fishes.
    Type of Medium: Online Resource
    ISSN: 1535-1459 , 1535-1467
    URL: Issue
    URL: Article
    DOI: 10.1002/rra.v36.8
    DOI: 10.1002/rra.3696
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2074114-5
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  • 5
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    Individual‐based modelling of hydropeaking effects on brown trout and Atlantic salmon in a regulated river
    Wiley ; 2023
    In:  River Research and Applications Vol. 39, No. 3 ( 2023-03), p. 522-537
    Details
    In: River Research and Applications, Wiley, Vol. 39, No. 3 ( 2023-03), p. 522-537
    Abstract: We developed an individual‐based model (IBM) to understand the effects of hydropeaking on growth, survival and distribution of age 0+ to 1+ juveniles for high‐conservation value populations of native brown trout ( Salmo trutta ) and Atlantic salmon ( S. salar ) in river Gullspång, Sweden. We parameterized and applied inSTREAM (7.2‐SD) and calibrated the model by comparing predicted versus observed growth under the current hydropeaking regime ( n = 〉 1,200 model fish for 365 days). Our objective was to model growth, survival and distribution under flow scenarios with and without hydropeaking. We observed that hydropeaking generally resulted in modest (~10%) negative effects on growth and survival of both species. Survival was more affected than was growth, smaller fish more affected than larger fish. On‐peak (high) hydropeaking flows resulted in less profitable feeding conditions (less growth) and higher predation (lower survival). Thus, inSTREAM 7.2‐SD appears to capture ecologically‐relevant behavioral patterns under hydropeaking, for example, habitat selection, in response to rapid flow changes. Understanding such patterns for large rivers via manipulative field studies, even if possible, would be time‐consuming and costly. Our study demonstrates the potential of IBMs as powerful tools for testing research questions and assessing and prioritizing alternative management strategies in regulated rivers.
    Type of Medium: Online Resource
    ISSN: 1535-1459 , 1535-1467
    URL: Issue
    URL: Article
    DOI: 10.1002/rra.v39.3
    DOI: 10.1002/rra.4037
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2074114-5
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  • 6
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    Temperature‐dependent competition between juvenile salmonids in small streams
    Wiley ; 2019
    In:  Freshwater Biology Vol. 64, No. 8 ( 2019-08), p. 1534-1541
    Details
    In: Freshwater Biology, Wiley, Vol. 64, No. 8 ( 2019-08), p. 1534-1541
    Abstract: Biotic interactions affect species distributions, and environmental factors that influence these interactions can play a key role when range shifts in response to environmental change are modelled. In a field experiment using enclosures, we studied the effects of the thermal habitat on intra‐ versus inter‐specific competition of juvenile Dolly Varden Salvelinus malma and white‐spotted charr Salvelinus leucomaenis , as measured by differences in specific growth rates during summer in allopatric and sympatric treatments. Previous laboratory experiments have shown mixed results regarding the importance of temperature‐dependent competitive abilities as a main driver for spatial segregation in stream fishes, and no study so far has confirmed its existence in natural streams. Under natural conditions in areas where the two species occur in sympatry, Dolly Varden dominate spring‐fed tributaries (cold, stable thermal regime), whereas both species often coexist in non‐spring‐fed tributaries (warm, unstable thermal regime). Enclosures (charr density = 6 per m 2 ) were placed in non‐spring‐fed (10–14°C) and spring‐fed (7–8°C) tributaries. In enclosures placed in non‐spring‐fed tributaries, Dolly Varden grew 0.81% per day in allopatry and had negative growth (−0.33% per day) in sympatry, whereas growth rates were similar in allopatry and sympatry in spring‐fed tributaries (0.68 and 0.58% per day). White‐spotted charr grew better in sympatry than in allopatry in both thermal habitats. In non‐spring‐fed tributaries, they grew 0.17 and 0.79% per day and in spring‐fed tributaries 0.46 and 0.75% per day in allopatry and sympatry, respectively. The negative effect of inter‐specific competition from white‐spotted charr on Dolly Varden thus depended on the thermal habitat. However, there was no strong evidence of a temperature‐dependent effect of intra‐ and inter‐specific competition on white‐spotted charr growth. Multiple factors may shape species distribution patterns, and we show that temperature may mediate competitive outcomes and thus coexistence in stream fish. These effects of temperature will be important to incorporate into mechanistic and dynamic species distribution models.
    Type of Medium: Online Resource
    ISSN: 0046-5070 , 1365-2427
    URL: Issue
    URL: Article
    DOI: 10.1111/fwb.2019.64.issue-8
    DOI: 10.1111/fwb.13325
    Language: English
    Publisher: Wiley
    Publication Date: 2019
    detail.hit.zdb_id: 2020306-8
    detail.hit.zdb_id: 121180-8
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  • 7
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    The suitability of Hester–Dendy macroinvertebrate samplers in fluctuating flows
    Wiley ; 2021
    In:  River Research and Applications Vol. 37, No. 6 ( 2021-07), p. 895-899
    Details
    In: River Research and Applications, Wiley, Vol. 37, No. 6 ( 2021-07), p. 895-899
    Abstract: Reliable methods for assessing the ecological status of degraded rivers are essential for evaluating restoration efforts in lotic habitats. Several methods are based on biological indicators, such as benthic macroinvertebrates. The Hester–Dendy multi‐plate sampler is a commonly used tool for sampling macroinvertebrates, but its performance under different environmental conditions is not well understood. In a laboratory experiment, we assessed if fluctuating and increasing water velocity influences the performance of Hester–Dendy samplers, by studying colonization of the samplers in relation to a pre‐determined composition of benthic macroinvertebrates. Biodiversity (Shannon‐Wiener index) of colonizing macroinvertebrates was higher in a constant than in a fluctuating flow treatment, but there was no effect on the number of colonizing individuals. The results suggest a potential bias in the interpretation of biodiversity data from sites with sub‐daily flow changes, for example, downstream of hydropeaking power plants.
    Type of Medium: Online Resource
    ISSN: 1535-1459 , 1535-1467
    URL: Issue
    URL: Article
    DOI: 10.1002/rra.v37.6
    DOI: 10.1002/rra.3805
    Language: English
    Publisher: Wiley
    Publication Date: 2021
    detail.hit.zdb_id: 2074114-5
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  • 8
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    Optimization of a sample preparation method for the metabolomic analysis of clinically relevant bacteria
    Elsevier BV ; 2011
    In:  Journal of Microbiological Methods Vol. 87, No. 1 ( 2011-10), p. 24-31
    Details
    In: Journal of Microbiological Methods, Elsevier BV, Vol. 87, No. 1 ( 2011-10), p. 24-31
    Type of Medium: Online Resource
    ISSN: 0167-7012
    URL: Article
    DOI: 10.1016/j.mimet.2011.07.001
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2011
    detail.hit.zdb_id: 1483012-7
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  • 9
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    Complete Remission with Reduction of High-Risk Clones following Haploidentical NK-Cell Therapy against MDS and AML
    American Association for Cancer Research (AACR) ; 2018
    In:  Clinical Cancer Research Vol. 24, No. 8 ( 2018-04-15), p. 1834-1844
    Details
    In: Clinical Cancer Research, American Association for Cancer Research (AACR), Vol. 24, No. 8 ( 2018-04-15), p. 1834-1844
    Abstract: Purpose: To evaluate the safety, efficacy, and immunobiological correlates of allogeneic NK-cell–based therapy in primary chemotherapy-refractory or relapsed high-risk myelodysplastic syndrome (MDS), secondary AML (MDS/AML), and de novo AML patients. Experimental Design: Sixteen patients received fludarabine/cyclophosphamide conditioning combined with total lymphoid irradiation followed by adoptive immunotherapy with IL2–activated haploidentical NK cells. Results: NK-cell infusions were well-tolerated, with only transient adverse events observed in the 16 patients. Six patients achieved objective responses with complete remission (CR), marrow CR, or partial remission (PR). Five patients proceeded to allogeneic hematopoietic stem cell transplantation (HSCT). Three patients are still free from disease & gt;3 years after treatment. All evaluable patients with objective responses (5/5 evaluable) had detectable donor NK cells at days 7/14 following infusion and displayed reduction of tumor cell clones, some of which carried poor prognosis mutations. Residual lin−CD34+CD123+CD45RA+ blast cells in responders had increased total HLA class I and HLA-E expression. Responding patients displayed less pronounced activation of CD8+ T cells and lower levels of inflammatory cytokines following NK-cell infusion. Intriguingly, despite omission of systemic IL2, all patients displayed increased frequencies of activated Ki-67+CD127−FoxP3+CD25hiCD4+ Treg cells of recipient origin following NK-cell therapy. Conclusions: Overall, this study suggests that high-risk MDS is responsive to NK-cell therapy and supports the use of haploidentical NK-cell infusions as a bridge to HSCT in refractory patients. Objective clinical responses and reduction of high-risk clones were associated with detectable donor-derived NK cells, immunoediting of residual blast cells, and less pronounced host immune activation. Clin Cancer Res; 24(8); 1834–44. ©2018 AACR.
    Type of Medium: Online Resource
    ISSN: 1078-0432 , 1557-3265
    URL: Article
    DOI: 10.1158/1078-0432.CCR-17-3196
    RVK:
    XA 36791
    Language: English
    Publisher: American Association for Cancer Research (AACR)
    Publication Date: 2018
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    detail.hit.zdb_id: 2036787-9
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  • 10
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    A 2-Pyridone-Amide Inhibitor Targets the Glucose Metabolism Pathway of Chlamydia trachomatis
    American Society for Microbiology ; 2015
    In:  mBio Vol. 6, No. 1 ( 2015-02-27)
    Details
    In: mBio, American Society for Microbiology, Vol. 6, No. 1 ( 2015-02-27)
    Abstract: Chlamydia trachomatis is a bacterial pathogen of humans that causes a common sexually transmitted disease as well as eye infections. It grows only inside cells of its host organism, within a parasitophorous vacuole termed the inclusion. Little is known, however, about what bacterial components and processes are important for C. trachomatis cellular infectivity. Here, by using a visual screen for compounds that affect bacterial distribution within the chlamydial inclusion, we identified the inhibitor KSK120. As hypothesized, the altered bacterial distribution induced by KSK120 correlated with a block in C. trachomatis infectivity. Our data suggest that the compound targets the glucose-6-phosphate (G-6P) metabolism pathway of C. trachomatis, supporting previous indications that G-6P metabolism is critical for C. trachomatis infectivity. Thus, KSK120 may be a useful tool to study chlamydial glucose metabolism and has the potential to be used in the treatment of C. trachomatis infections.
    Type of Medium: Online Resource
    ISSN: 2161-2129 , 2150-7511
    URL: Article
    DOI: 10.1128/mBio.02304-14
    Language: English
    Publisher: American Society for Microbiology
    Publication Date: 2015
    detail.hit.zdb_id: 2557172-2
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