In:
Asian Journal of Organic Chemistry, Wiley, Vol. 12, No. 6 ( 2023-06)
Abstract:
The first example of merging photoredox catalysis and copper catalysis for 1,4‐difunctionalization of 1,3‐enynes via 1,5‐HAT (hydrogen atom transfer) has been developed. The synthetic strategy exploits a radical translocation from an oxygen‐centered to a carbon‐centered radical with a subsequent radical addition to the 1,3‐enynes, affording tetrasubstituted allenenitriles in up to 90% yield. This strategy has mild reaction conditions, broad substrate scope and excellent functional group tolerance.
Type of Medium:
Online Resource
ISSN:
2193-5807
,
2193-5815
DOI:
10.1002/ajoc.202300234
Language:
English
Publisher:
Wiley
Publication Date:
2023
detail.hit.zdb_id:
2679333-7
Permalink