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  • 1
    Online Resource
    Online Resource
    Treatment Recommendations Following 3-Day Masked Continuous Glucose Monitoring (CGM) in Youth With Type 1 Diabetes
    SAGE Publications ; 2014
    In:  Journal of Diabetes Science and Technology Vol. 8, No. 3 ( 2014-05), p. 494-497
    Details
    In: Journal of Diabetes Science and Technology, SAGE Publications, Vol. 8, No. 3 ( 2014-05), p. 494-497
    Abstract: Glycemic control remains suboptimal in youth with type 1 diabetes. Retrospective continuous glucose monitoring (CGM) has demonstrated utility in fine-tuning diabetes management by detecting postprandial hyperglycemia and hypoglycemia. In this study, we explored the process of 3-day masked CGM use, subsequent treatment recommendations, and impact on A1c in a clinic-based sample of youth with type 1 diabetes. Methods: Over 2 years, 122 youth were referred for masked CGM. Patients/families completed a diary of blood glucose levels, insulin doses, food intake, and exercise during CGM use. A1c was assessed pre- and 2-3 months post-CGM. Treatment recommendations were formulated using data from CGM reports and diaries. Results: Mean age was 14.3 ± 3.9 years, diabetes duration was 7.5 ± 4.7 years, and A1c was 8.5 ± 1.1% (69 ± 12 mmol/mol); 61% were pump-treated. Patients received an average of 3.1 ± 1.1 treatment recommendations following review of the CGM report. Most (80%) received reinforcement of the importance of preprandial bolusing; 37% received a recommendation regarding advanced insulin management (use of combination boluses/attend to active insulin). Receipt of the latter recommendation was related to A1c improvement ≥0.5% (OR: 4.0, P 〈 .001). Conclusions: Masked CGM offers opportunities to guide advanced insulin management (by injection or pump), which may yield A1c improvements in youth with type 1 diabetes.
    Type of Medium: Online Resource
    ISSN: 1932-2968 , 1932-2968
    URL: Article
    DOI: 10.1177/1932296814528135
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2014
    detail.hit.zdb_id: 2467312-2
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  • 2
    Online Resource
    Online Resource
    Youth and Parent Measures of Self-Efficacy for Continuous Glucose Monitoring: Survey Psychometric Properties
    Mary Ann Liebert Inc ; 2015
    In:  Diabetes Technology & Therapeutics Vol. 17, No. 5 ( 2015-05), p. 327-334
    Details
    In: Diabetes Technology & Therapeutics, Mary Ann Liebert Inc, Vol. 17, No. 5 ( 2015-05), p. 327-334
    Type of Medium: Online Resource
    ISSN: 1520-9156 , 1557-8593
    URL: Article
    DOI: 10.1089/dia.2014.0366
    Language: English
    Publisher: Mary Ann Liebert Inc
    Publication Date: 2015
    detail.hit.zdb_id: 2004914-6
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  • 3
    Online Resource
    Online Resource
    1189-P: Challenges Recruiting Adolescents and Young Adults (AYA) with Type 1 Diabetes and Higher A1Cs for Clinical Research
    American Diabetes Association ; 2024
    In:  Diabetes Vol. 73, No. Supplement_1 ( 2024-06-14)
    Details
    In: Diabetes, American Diabetes Association, Vol. 73, No. Supplement_1 ( 2024-06-14)
    Abstract: Introduction: Recruiting a representative study sample is critical but can be challenging. We assessed potential differences between AYA with T1D who consented vs declined to participate in a 2-year RCT aimed at improving glycemic outcomes and reducing diabetes distress. Methods: AYA were recruited at 2 US sites for a study involving monthly virtual 1-1 psychoeducational sessions. Eligibility criteria included age 14-25 years, T1D ≥1 year, and A1c 7-13%. Results: Over 15 months, we approached 482 potential participants; 217 (45%) consented, 232 (48%) declined, and 33 (7%) were ineligible. Most AYA were identified via clinic schedules (77%). Other recruitment methods were: participation in a previous study (14%), recruitment flyer (5%), provider referral (4%), and social media (1%). Reasons for decline were: too busy/not a good time (n=41, 18%), not interested (n=29, 13%), other/no reason given (n=7, 3%), and passive decline (expressed interest but no decision before enrollment closed) (n=155, 67%). There was no difference in the number of contacts made to those who consented vs declined (median=2 for both, range=1-8). Limited demographic data at 1 site for 217 potential participants (105 consented, 112 declined) showed no difference in % consented according to age (14-18 years: 46% consented; 19-25: 50% consented; p=.58) or SES using Social Deprivation Index (higher SES: 47% consented; lower SES: 51% consented; p=.49). However, there was a difference by A1c (7-8.4%: 59% consented; 8.5-13%: 39% consented; p=.002). Further, 65% of those with A1c 8.5-13% who declined were passive declines (compared to 51% of decliners with A1c 7-8.4%), suggesting that they had some interest but no follow-through. Number of contacts did not differ by age, SES, or A1c. Conclusion: AYA with suboptimal glycemic control, often the target of research, may hesitate to participate in clinical trials. Creative outreach and extra effort (e.g., more contacts) may help to recruit them for future studies. Disclosure L.K. Volkening: None. B. Morrissey: None. S.A. Alamarie: None. C. Herndon: None. A.K. Schneider-Utaka: None. A. Adam: None. S. Hanes: None. S. Ojukwu: None. K.K. Hood: Consultant; Cecelia Health, Sanofi. L.M. Laffel: Consultant; Dexcom, Inc. Advisory Panel; Medscape, Medtronic, Vertex Pharmaceuticals Incorporated. Consultant; Novo Nordisk. Advisory Panel; Lilly Diabetes, Provention Bio, Inc., Sanofi-Aventis U.S., Janssen Pharmaceuticals, Inc., MannKind Corporation. Funding National Institutes of Health (R01DK129479)
    Type of Medium: Online Resource
    ISSN: 0012-1797
    URL: Article
    DOI: 10.2337/db24-1189-P
    Language: English
    Publisher: American Diabetes Association
    Publication Date: 2024
    detail.hit.zdb_id: 1501252-9
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  • 4
    Online Resource
    Online Resource
    The Blood Glucose Monitoring Communication Questionnaire
    American Diabetes Association ; 2004
    In:  Diabetes Care Vol. 27, No. 11 ( 2004-11-01), p. 2610-2615
    Details
    In: Diabetes Care, American Diabetes Association, Vol. 27, No. 11 ( 2004-11-01), p. 2610-2615
    Abstract: OBJECTIVE—The aim of this study was to present the psychometric properties of a new tool for evaluating affective response to blood glucose monitoring (BGM) in youths with type 1 diabetes and their parents. RESEARCH DESIGN AND METHODS—Study participants included 153 youths with type 1 diabetes and their parents. Each youth and parent completed the Blood Glucose Monitoring Communication (BGMC) questionnaire, Diabetes Family Conflict Scale, and Pediatric Quality of Life Inventory. Statistical analyses evaluated the psychometric properties of the BGMC questionnaires and their association with glycemic outcomes. RESULTS—Youth and parent BGMC questionnaires had acceptable internal consistency (youth, α = 0.77; parent, α = 0.82) and 1-year test-retest reliability (youth, r = 0.60; parent, r = 0.80). Higher BGMC questionnaire scores (indicating more negative affect) showed a strong association with higher levels of diabetes-specific family conflict (youth, r = 0.33; parent, r = 0.44) and poorer health-related psychosocial quality of life (youth, r = −0.50; parent, r = −0.42). Higher BGMC questionnaire scores were also associated with poorer glycemic control (youth, r = 0.28; parent, r = 0.20), even when the effects of diabetes-specific family conflict and psychosocial quality of life were controlled. Youths with BGMC questionnaire scores in the upper quartile had A1c values 1 percentage point higher (9.1%) than youths with scores in the lowest quartile (8.0%). CONCLUSIONS—The BGMC questionnaires have strong psychometric properties and are convenient measures of affect specific to BGM. Further, BGM affect is associated with glycemic outcomes and may provide a unique contribution to factors associated with glycemic control in youths.
    Type of Medium: Online Resource
    ISSN: 0149-5992 , 1935-5548
    URL: Article
    DOI: 10.2337/diacare.27.11.2610
    Language: English
    Publisher: American Diabetes Association
    Publication Date: 2004
    detail.hit.zdb_id: 1490520-6
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  • 5
    Online Resource
    Online Resource
    A Randomized Pilot Trial Using Mobile Health and Financial Incentives to Motivate Heart-Healthy Behaviors in Adolescents With Type 1 Diabetes
    SAGE Publications ; 2023
    In:  Journal of Diabetes Science and Technology Vol. 17, No. 3 ( 2023-05), p. 855-856
    Details
    In: Journal of Diabetes Science and Technology, SAGE Publications, Vol. 17, No. 3 ( 2023-05), p. 855-856
    Type of Medium: Online Resource
    ISSN: 1932-2968 , 1932-2968
    URL: Article
    DOI: 10.1177/19322968231155151
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2467312-2
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  • 6
    Online Resource
    Online Resource
    Associations of Executive Function With Diabetes Management and Glycemic Control in Adolescents With Type 1 Diabetes
    American Diabetes Association ; 2023
    In:  Diabetes Spectrum Vol. 36, No. 1 ( 2023-02-01), p. 23-32
    Details
    In: Diabetes Spectrum, American Diabetes Association, Vol. 36, No. 1 ( 2023-02-01), p. 23-32
    Abstract: The aims of this study were to assess domains of executive function in relation to diabetes management and glycemic control in adolescents with type 1 diabetes and to compare adolescent self-report and parent proxy-report of adolescent executive function. Methods Adolescents with type 1 diabetes (N = 169, 46% female, age 15.9 ± 1.3 years) and their parents completed self-report and parent proxy-report versions of the Behavior Rating Inventory of Executive Function (BRIEF). Results Self-report and parent proxy-report BRIEF T scores were moderately to strongly correlated; parent proxy scores were significantly higher than self-report scores. Executive function problems (Global Executive Composite T score ≥60) occurred in 9% of adolescents by self-report and 26% by parent proxy-report. For almost all Metacognition Index scales, elevated (T score ≥60) parent proxy scores were associated with lower adherence, lower adolescent diabetes self-efficacy, and more parent involvement in diabetes management. Elevated scores on several Metacognition Index scales were associated with less pump use (Plan/Organize by self-report, Initiate by parent proxy-report, and Monitor by parent proxy-report) and higher A1C (Plan/Organize by self-report and parent proxy-report and Organization of Materials by parent proxy-report). The only significant associations for the Behavioral Regulation Index scales occurred for adherence (by parent proxy-report) and diabetes self-efficacy (by self-report and parent-report). Conclusion Adolescents with type 1 diabetes who have problems with metacognition may need additional support for diabetes self-management.
    Type of Medium: Online Resource
    ISSN: 1040-9165 , 1944-7353
    URL: Article
    DOI: 10.2337/ds21-0107
    Language: English
    Publisher: American Diabetes Association
    Publication Date: 2023
    detail.hit.zdb_id: 2043905-2
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  • 7
    Online Resource
    Online Resource
    Improving dietary quality in youth with type 1 diabetes: randomized clinical trial of a family-based behavioral intervention
    Springer Science and Business Media LLC ; 2015
    In:  International Journal of Behavioral Nutrition and Physical Activity Vol. 12, No. 1 ( 2015-12)
    Details
    In: International Journal of Behavioral Nutrition and Physical Activity, Springer Science and Business Media LLC, Vol. 12, No. 1 ( 2015-12)
    Type of Medium: Online Resource
    ISSN: 1479-5868
    URL: Article
    DOI: 10.1186/s12966-015-0214-4
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2015
    detail.hit.zdb_id: 2134691-4
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  • 8
    Online Resource
    Online Resource
    Health‐related quality of life in youth with type 1 diabetes: Associations with multiple comorbidities and mental health conditions
    Wiley ; 2021
    In:  Diabetic Medicine Vol. 38, No. 10 ( 2021-10)
    Details
    In: Diabetic Medicine, Wiley, Vol. 38, No. 10 ( 2021-10)
    Abstract: This cross‐sectional study examined the associations of comorbid conditions on health‐related quality of life (HRQOL) in 601 youth with type 1 diabetes. We evaluated associations between number of comorbid conditions (0, 1, ≥2) and particular comorbid conditions and youth HRQOL by self‐report and parent proxy‐report. Research design and methods Youth with type 1 diabetes, aged 5–18 years, and their parents completed the PedsQL 4.0 Generic Core Scales self‐report and parent proxy‐report, respectively; they also reported youths' comorbid medical and mental health conditions. Separate linear regression models tested the relationship between number of comorbid conditions and specific comorbid conditions with youth‐reported and parent proxy‐reported HRQOL. Results Youth with ≥2 comorbid conditions had significantly lower HRQOL by both self‐ and parent proxy‐reports compared with youth with 0 or 1 comorbid condition (youth self‐report: 0: 85 ± 12, 1: 85 ± 13, 2+: 78 ± 16, p  =  〈 0.0001; parent proxy‐report: 0: 83 ± 12, 1: 81 ± 13, 2+: 74 ± 15, p  =  〈 0.0001). Amongst the comorbid conditions, only a mental health comorbidity was associated with lower HRQOL. For youth and parent proxy‐reports, both the number of comorbidities (≥2) and the presence of a mental health comorbidity were significantly associated with lower HRQOL. Conclusions Health‐related quality of life seems to be preserved in youth with type 1 diabetes unless confronted by multiple comorbidities as reported by youth and their parents. Our findings highlight the importance of tracking the presence of multiple comorbid conditions, possibly by reviewing problem and medication lists in the medical record, as well as screening for and addressing mental health conditions in routine diabetes care.
    Type of Medium: Online Resource
    ISSN: 0742-3071 , 1464-5491
    URL: Issue
    URL: Article
    DOI: 10.1111/dme.v38.10
    DOI: 10.1111/dme.14617
    Language: English
    Publisher: Wiley
    Publication Date: 2021
    detail.hit.zdb_id: 2019647-7
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  • 9
    Online Resource
    Online Resource
    Depressive Symptoms at Critical Times in Youth With Type 1 Diabetes: Following Type 1 Diabetes Diagnosis and Insulin Pump Initiation
    Elsevier BV ; 2018
    In:  Journal of Adolescent Health Vol. 62, No. 2 ( 2018-02), p. 219-225
    Details
    In: Journal of Adolescent Health, Elsevier BV, Vol. 62, No. 2 ( 2018-02), p. 219-225
    Type of Medium: Online Resource
    ISSN: 1054-139X
    URL: Article
    DOI: 10.1016/j.jadohealth.2017.09.017
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2018
    detail.hit.zdb_id: 2006608-9
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  • 10
    Online Resource
    Online Resource
    550-P: Unique Associations of Depressive Symptoms and Diabetes Distress with Quality of Life (QoL) in Youth with Type 1 Diabetes (T1D)
    American Diabetes Association ; 2021
    In:  Diabetes Vol. 70, No. Supplement_1 ( 2021-06-01)
    Details
    In: Diabetes, American Diabetes Association, Vol. 70, No. Supplement_1 ( 2021-06-01)
    Abstract: Youth with T1D often experience emotional distress, which can negatively impact QoL. We sought to understand associations of depressive symptoms and diabetes distress with QoL in youth with T1D. Participants (N=420; 50% male; ages 8-17 years; T1D duration 6.4±3.7 (M±SD) years; A1c 8.3±1.0%; 69% pump treated; 70% having parent with college degree) completed the Pediatric Quality of Life Inventory Generic Core Scales (PedsQL)and measures of depressive symptoms (Center for Epidemiologic Studies Depression Scale [CESD]) and diabetes distress (Problem Areas in Diabetes-Pediatric version [PAID-Peds] ). Multivariable linear modeling determined independent associations of depressive symptoms and diabetes distress with total, physical, and psychosocial QoL, adjusting for sex, age, T1D duration, A1c, pump therapy, insulin dose, and parent education. Total PedsQL score was 85±13, (physical subscale 89±12, psychosocial subscale 82±15); CESD score was 9±9; PAID-Peds score was 37±24. CESD and PAID-Peds were both correlated with A1c (CESD: p=.01, PAID-Peds: p & lt;.0001); QoL scales were not correlated with A1c. CESD and PAID-Peds were correlated with total, physical and psychosocial QoL (all p & lt;.0001). In multivariable analyses, more depressive symptoms were associated with poorer total (∆R2=.52, p & lt;.0001), physical (∆R2=.35, p & lt;.0001), and psychosocial (∆R2=.51, p & lt;.0001) QoL, adjusting for diabetes distress and sociodemographic/diabetes factors. More diabetes distress was associated with poorer total (∆R2=.05, p & lt;.0001) and psychosocial (∆R2=.06, p & lt; .0001) QoL, adjusting for depressive symptoms and sociodemographic/diabetes factors; more diabetes distress marginally contributed to poorer physical QoL (∆R2=.01, p=.002). Findings suggest unique, negative associations of both depressive symptoms and diabetes distress with QoL. Targeting both depressive symptoms and diabetes distress may help improve QoL in youth with T1D. Disclosure A. Shapira: None. L. K. Volkening: None. L. M. Laffel: Consultant; Self; AstraZeneca, Boehringer Ingelheim International GmbH, Dexcom, Inc., Dompe, Insulogic LLC, Janssen Pharmaceuticals, Inc., Laxmi Therapeutic Devices, LifeScan, Lilly Diabetes, Medtronic, Provention Bio, Inc. Funding National Institutes of Health (R01DK089349, R01DK095273, T32DK007260, P30DK036836); JDRF (2-SRA-2014-253-M-B)
    Type of Medium: Online Resource
    ISSN: 0012-1797 , 1939-327X
    URL: Article
    DOI: 10.2337/db21-550-P
    Language: English
    Publisher: American Diabetes Association
    Publication Date: 2021
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