In:
Acta Radiologica, SAGE Publications, Vol. 38, No. 6 ( 1997-11), p. 970-977
Abstract:
Purpose: HIV-infected patients show a high incidence of abdominal disease. This investigation was made to determine whether abdominal CT provided prognostically relevant information in these patients Material and Methods: Images from 533 abdominal CT examinations in 339 HIV-infected patients were retrospectively reviewed for signs of abdominal disease, and correlated with clinical data and survival rates. the Kaplan-Meier analysis and rank testing of survival, and proportional hazards regression were used to define prognostic clinical and imaging findings Results: of the 339 patients, 278 (82%) showed abnormal abdominal findings on CT. Median survival was 29 months. of the imaging findings, hepatic masses (n=11), pathologically enlarged lymph nodes (n=48), and ascites (n=7) were associated with poor survival, giving a median survival of respectively 13 months, 15 months, and less than 1 month. These three features showed no association with CD4 + -T-lymphocyte count or CDC category. Main determinants of survival were a low CD4 + -T-lymphocyte count, and certain abnormal CT findings. Splenomegaly (n=147), hepatomegaly (n=144), and lymphadenopathy (n=111) were the most common abdominal findings on CT but lacked prognostic relevance Conclusion: Abdominal CT offered prognostic implications in HIV-infected patients and might serve in risk stratification in selected patients. CT features such as hepatic masses, grossly enlarged lymph nodes, or ascites indicate advanced immunosuppression
Type of Medium:
Online Resource
ISSN:
0284-1851
,
1600-0455
DOI:
10.1080/02841859709172112
Language:
English
Publisher:
SAGE Publications
Publication Date:
1997
detail.hit.zdb_id:
2024579-8
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