In:
European Radiology, Springer Science and Business Media LLC, Vol. 30, No. 12 ( 2020-12), p. 6838-6846
Abstract:
To determine normal pericoronary adipose tissue mean attenuation (PCAT MA ) values for left the anterior descending (LAD), left circumflex (LCX), and right coronary artery (RCA) in patients without plaques on coronary CT angiography (cCTA), taking into account tube voltage influence. Methods This retrospective study included 192 patients (76 (39.6%) men; median age 49 years (range, 19–79)) who underwent cCTA with third-generation dual-source CT for the suspicion of CAD between 2015 and 2017. We selected patients without plaque on cCTA. PCAT MA was measured semi-automatically on cCTA images in the proximal segment of the three main coronary arteries with 10 mm length. Paired t -testing was used to compare PCAT MA between combinations of two coronary arteries within each patient, and one-way ANOVA testing was used to compare PCAT MA in different kV groups. Results The overall mean ± standard deviation (SD) PCAT MA was − 90.3 ± 11.1 HU. PCAT MA in men was higher than that in women: − 88.5 ± 10.5 HU versus − 91.5 ± 11.3 HU ( p = 0.001). PCAT MA of LAD, LCX, and RCA was − 92.4 ± 11.6 HU, − 88.4 ± 9.9 HU, and − 90.2 ± 11.4 HU, respectively. Pairwise comparison of the arteries showed significant difference in PCAT MA : LAD and LCX ( p 〈 0.001), LAD and RCA ( p = 0.009), LCX and RCA ( p = 0.033). PCAT MA of the 70 kV, 80 kV, 90 kV, 100 kV, and 120 kV groups was − 95.6 ± 9.6 HU, − 90.2 ± 11.5 HU, − 87.3 ± 9.9 HU, − 82.7 ± 6.2 HU, and − 79.3 ± 6.8 HU, respectively ( p 〈 0.001). Conclusions In patients without plaque on cCTA, PCAT MA varied by tube voltage, with minor differences in PCAT MA between coronary arteries (LAD, LCX, RCA). PCAT MA values need to be interpreted taking into account tube voltage setting. Key Points • In patients without plaque on cCTA, PCAT MA differs slightly by coronary artery (LAD, LCX, RCA). • Tube voltage of cCTA affects PCAT MA measurement, with mean PCAT MA increasing linearly with increasing kV. • For longitudinal cCTA analysis of PCAT MA , the use of equal kV setting is strongly recommended.
Type of Medium:
Online Resource
ISSN:
0938-7994
,
1432-1084
DOI:
10.1007/s00330-020-07069-0
Language:
English
Publisher:
Springer Science and Business Media LLC
Publication Date:
2020
detail.hit.zdb_id:
1472718-3
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