In:
European Oncology & Haematology, Touch Medical Media, Ltd., Vol. 10, No. 01 ( 2014), p. 17-
Abstract:
The management of patients with locally advanced rectal cancer (LARC) has evolved with the aim of reducing local recurrence and improving survival. Current practice has developed from refinements in surgical technique, the availability of different types of preoperative imaging, the selective or blanket use of neoadjuvant treatment (usually radiation) and sophisticated efforts exploring multimodality treatments to achieve organ preservation. Both short-course preoperative radiotherapy (SCPRT) and long-course chemoradiation (CRT) are considered standard neoadjuvant strategies, which are advocated in different parts of the world. New techniques in the delivery of radiotherapy, such as intensity-modulated radiotherapy (IMRT), may allow more precise dosing to the target volume (tumour and/or locoregional lymph nodes) and limit radiation doses to critical normal structures; however, current schedules of SCPRT and CRT impact on late function, and if they do not improve survival in resectable cancers, can they be omitted in selected cases?
Type of Medium:
Online Resource
ISSN:
2045-5275
DOI:
10.17925/EOH.2014.10.1.17
Language:
English
Publisher:
Touch Medical Media, Ltd.
Publication Date:
2014
detail.hit.zdb_id:
2743200-2
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