In:
Journal of Histochemistry & Cytochemistry, SAGE Publications, Vol. 51, No. 4 ( 2003-04), p. 541-544
Abstract:
We investigated the intracellular distribution of the mRNAs corresponding to the three non-allelic CaM genes in cultured hippocampal cells by in situ hybridization with digoxigenin-labeled gene-specific riboprobes. In neurons the perikaryon was heavily stained and strong dendritic mRNA targeting was detected for all three CaM genes. The color labeling exhibited a punctate distribution, suggesting that CaM mRNAs are transported in RNA granules. Immunocytochemistry for S100 demonstrated that glial cells express CaM mRNAs at a very low level. A minority of the cultured cells were negative for either labeling.
Type of Medium:
Online Resource
ISSN:
0022-1554
,
1551-5044
DOI:
10.1177/002215540305100416
Language:
English
Publisher:
SAGE Publications
Publication Date:
2003
detail.hit.zdb_id:
1421306-0
SSG:
12
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