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  • 1
    Online Resource
    Online Resource
    Efficacy and Safety of Methotrexate in Combination with Mini Pulse Doses of Methylprednisolone in Severe Alopecia Areata. The Vietnamese Experience
    Scientific Foundation SPIROSKI ; 2019
    In:  Open Access Macedonian Journal of Medical Sciences Vol. 7, No. 2 ( 2019-01-23), p. 200-203
    Details
    In: Open Access Macedonian Journal of Medical Sciences, Scientific Foundation SPIROSKI, Vol. 7, No. 2 ( 2019-01-23), p. 200-203
    Abstract: BACKGROUND: Treatment of severe alopecia areata remains very difficult, especially in alopecia areata totalis and alopecia areata universalis. Methotrexate is known to be effective in the treatment of severe and chronic autoimmune disorders. OBJECTIVE: To assess the effectiveness and safety of MTX in combination with mini pulse dose of methylprednisolone in the treatment of severe alopecia areata. PATIENTS AND METHODS: The open, uncontrolled study compared pre-treatment and after-treatment. Thirty-eight patients (age 16-64) with severity AA (SALT score 〉 50 %) visiting National hospital of Dermatology and Venereology from April-2004 to September-2015 were enrolled. All patients received oral methylprednisolone 24mg/day for 3 consecutive days of a week in combination with oral MTX 7,5 mg weekly. This regimen is maintained up to 12 weeks and follow-up until to 6 months. RESULTS: After 6 months, 60.5% of patients show complete hair growth (good response) and 18.4% shows the medium response. There is a significant SALT score reduction: mean baseline SALT score 84.39 ± 17.03 compared to mean post-treatment SALT score 24.19 ± 29.42. Good clinical improvement noted in after 3 months. We do not observe any side- effects related to oral MTX and oral methylprednisolone, and no patients had to withdrawal treatment due to side- effects. CONCLUSION: Combination Methotrexate and mini pulse dose of methylprednisolone are effective and safe in treatment severity alopecia areata.
    Type of Medium: Online Resource
    ISSN: 1857-9655
    URL: Article
    DOI: 10.3889/oamjms.2019.004
    Language: Unknown
    Publisher: Scientific Foundation SPIROSKI
    Publication Date: 2019
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  • 2
    Online Resource
    Online Resource
    MÔ TẢ MỘT SỐ ĐẶC ĐIỂM VỀ DUNG NẠP, CẢM QUAN CỦA NGƯỜI BỆNH HẬU PHẪU SỬ DỤNG SẢN PHẨM DINH DƯỠNG Y HỌC SUPPRO
    Vietnam Medical Journal, Vietnam Medical Association ; 2023
    In:  Tạp chí Y học Việt Nam Vol. 523, No. 1 ( 2023-02-24)
    Details
    In: Tạp chí Y học Việt Nam, Vietnam Medical Journal, Vietnam Medical Association, Vol. 523, No. 1 ( 2023-02-24)
    Abstract: Mục tiêu: mô tả tình trạng dinh dưỡng của bệnh nhân trước phẫu thuật và sau phẫu thuật có nuôi dưỡng kết hợp bằng sản phẩm suppro và cảm quan sản phẩm dinh dưỡng y học suppro. Phương pháp nghiên cứu: Can thiệp lâm sàng không đối chứng 30 bệnh nhân được nuôi dưỡng kết hợp sản phẩm Suppro tại bệnh viện Hữu Nghị Việt Đức từ 7/2022 - 9/2022. Kết quả: Tỷ lệ bệnh nhân suy dinh dưỡng có chỉ số BMI 〈 18,5 trước phẫu thuật là 10% sau phẫu thuật là 20%. 100% bệnh nhân sử dụng sản phẩm suppro thấy bột tơi mịn, thơm, vị dễ uống. Năng lượng nuôi dưỡng trung bình của bệnh nhân những ngày đầu sau phẫu thuật là 1195,3 ± 323 (kcal). Chỉ số albumin, prealbumin trung bình của bệnh nhân giảm sau phẫu thuật có ý nghĩa thống kê. Kết luận: Suppro có tính an toàn về màu sắc mùi vị cảm quan.
    Type of Medium: Online Resource
    ISSN: 1859-1868
    URL: Article
    DOI: 10.51298/vmj.v523i1.4463
    Language: Unknown
    Publisher: Vietnam Medical Journal, Vietnam Medical Association
    Publication Date: 2023
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  • 3
    Online Resource
    Online Resource
    The effectiveness of local surgical technique in treatment of axillary bromhidrosis
    Scientific Foundation SPIROSKI ; 2019
    In:  Open Access Macedonian Journal of Medical Sciences Vol. 7, No. 2 ( 2019-01-29), p. 187-191
    Details
    In: Open Access Macedonian Journal of Medical Sciences, Scientific Foundation SPIROSKI, Vol. 7, No. 2 ( 2019-01-29), p. 187-191
    Abstract: BACKGROUND: Up to now, surgical excision of apocrine glands still has been a method that yields high treatment results and low rate of odour recurrent for patients, but many people worry about some serious complications that have been observed postoperatively, such as hematoma and skin necrosis. These prolong wound healing, leading to unsightly scars in the axillary fossae. AIM: We conducted this research to investigate the effects and complications of our surgical technique for axillary bromhidrosis. METHODS: Forty-three patients with axillary bromhidrosis were treated. An elliptical incision was made at a central portion of the area marked, with both tips of the ellipse along the axillary crease. The elliptical skin with the subcutaneous tissue was removed en lock. The adjacent skin was undermined to the periphery of the hair-bearing area with straight scissors. The undermined subcutaneous tissue was removed with curved scissors, and the skin was defatted to become a full-thickness skin flap. Any suspected hemorrhagic spots were immediately coagulated electrosurgically. Appropriate drains were placed, and the treated area was covered with thick gauze to each axilla. Arm movement was strictly controlled in the first 3 days post-operatively. RESULTS: Thirty-one patients have been followed up and evaluated for 6 months. 56 out of 62 axillae (90.3%) showed good to excellent results for malodor elimination. All patients reported a reduction in axillary sweating. There were two axillae of skin necrosis and three axillae of hematoma, with one patient receiving an anticoagulant from a cardiologist after the first day of surgery, to treat heart valve disease. The Dermatology Life Quality Index (DLQI) score decreased significantly, and the quality of life improved after the operation. CONCLUSION: Our technique is a simple surgical procedure and easy to perform helping to achieve results for high malodor elimination, with almost no serious complications. Patient’s life quality improved significantly after the operation.
    Type of Medium: Online Resource
    ISSN: 1857-9655
    URL: Article
    DOI: 10.3889/oamjms.2019.133
    Language: Unknown
    Publisher: Scientific Foundation SPIROSKI
    Publication Date: 2019
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  • 4
    Online Resource
    Online Resource
    Successful Treatment of Intralesional Bleomycin in Keloids of Vietnamese Population
    Scientific Foundation SPIROSKI ; 2019
    In:  Open Access Macedonian Journal of Medical Sciences Vol. 7, No. 2 ( 2019-01-29), p. 298-299
    Details
    In: Open Access Macedonian Journal of Medical Sciences, Scientific Foundation SPIROSKI, Vol. 7, No. 2 ( 2019-01-29), p. 298-299
    Abstract: BACKGROUND: Keloid is an overactive condition of the skin tissue to early lesions characterised by proliferation of fibroblasts, excessive collagen production in the lesion. Treatment of keloids is a big challenge because of the poor response rate and high risk of recurrence after treatment. We found that bleomycin offers promise in the treatment of keloids. AIM: To evaluate the efficacy of bleomycin injected in the injury for keloids treatment. METHODS: The treatment was carried out in 55 patients having 120 keloids of different sizes and locations. Average treatments were 4 times. RESULTS: Complete flattening was 70.8%, highly significant flattening was 8.3%, no patient of minimal flattening. Systemic side-effects of bleomycin were not evaluated, but local side-effects were mainly pains (100%), blisters (78.3%), ulceration (5.8%), and hyperpigmentation (56.7%). CONCLUSION: The percentage of patients recurring 6, 12, 15, 18 months after the last treatment were 3.8, 15.4, 45.5, 50%, respectively.
    Type of Medium: Online Resource
    ISSN: 1857-9655
    URL: Article
    DOI: 10.3889/oamjms.2019.099
    Language: Unknown
    Publisher: Scientific Foundation SPIROSKI
    Publication Date: 2019
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  • 5
    Online Resource
    Online Resource
    Cross-ownership in the banking system in Vietnam
    Valley International ; 2024
    In:  International Journal of Scientific Research and Management (IJSRM) Vol. 12, No. 02 ( 2024-02-17), p. 5866-5879
    Details
    In: International Journal of Scientific Research and Management (IJSRM), Valley International, Vol. 12, No. 02 ( 2024-02-17), p. 5866-5879
    Abstract: The banking industry is an important component of the economy, contributing significantly to economic development and national growth. A sustainable and effective banking system will bring many benefits to the economy, minimizing disadvantages to society and the environment. The banking sector in Vietnam is currently undergoing comprehensive restructuring efforts aimed at enhancing operational efficiency and ensuring safety and sustainable development within the context of economic integration. While cross-ownership is deemed normal in economies reliant on credit, the situation in Vietnam is complicated by underdeveloped inspection and supervision activities. This raises concerns about the potential negative impacts of cross-ownership on the overall efficiency of the economy, with particular emphasis on its ramifications for the banking and financial sector. In this paper, we aim to explore the complex world of cross-ownership, taking a closer look at how it's influencing the global business scene and, more importantly, shaping the banking sector in Vietnam. Our focus is on unraveling the various aspects of cross-ownership, understanding its prevalence worldwide, and delving into the implications it holds
    Type of Medium: Online Resource
    ISSN: 2321-3418
    URL: Article
    DOI: 10.18535/ijsrm/v12i02.em05
    Language: English
    Publisher: Valley International
    Publication Date: 2024
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  • 6
    Online Resource
    Online Resource
    Successful Treatment of Intralesional Triamcilonon Acetonide Injection in Keloid Patients
    Scientific Foundation SPIROSKI ; 2019
    In:  Open Access Macedonian Journal of Medical Sciences Vol. 7, No. 2 ( 2019-01-28), p. 275-278
    Details
    In: Open Access Macedonian Journal of Medical Sciences, Scientific Foundation SPIROSKI, Vol. 7, No. 2 ( 2019-01-28), p. 275-278
    Abstract: AIM: Evaluation the effect of intralesional corticosteroid injection on keloid, at the National Hospital of Dermatology and Venereology from 1/2009 to 12/2009. METHODS: A group of 65 patients with keloid were randomly assigned into three groups. In the studied group, 33 patients were intralesionally injected 7.5 mg/1 cm2 of TCA. In the control group, TAC 32 patients were intralesionally injected 15 mg/1 cm2 of TCA. The result was evaluated basing on the criteria of Henderson (1998) and El-Tonsy (1996). RESULTS: In comparison between 2 groups, good to excellent improvement in the studied group was statistically higher than the control group (90.7% versus 68.7%; p 〈 0.05). After each injection, the thickness of the scar was reduced 1.24 ± 0.53 mm in the studied group and 0.81 ± 0.39 mm in the control group. The disappearance of pain and itching after treatment were 86.6% and 95.5% in the studied group and 78.1% and 80% in the control group (p 〉 0.05). Ulceration, acne and troublesome with menstrual cycles were sometimes were noted more frequently in the control group than in the studied group. CONCLUSION: Intralesional triamcinolone acetonide injection had a good result, and 7.5 mg/1 cm2 scar is the best dose for treatment of keloid.
    Type of Medium: Online Resource
    ISSN: 1857-9655
    URL: Article
    DOI: 10.3889/oamjms.2019.093
    Language: Unknown
    Publisher: Scientific Foundation SPIROSKI
    Publication Date: 2019
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  • 7
    Online Resource
    Online Resource
    The Efficacy of a Two-Fold Increase of H1-Antihistamine in the Treatment of Chronic Urticaria - the Vietnamese Experience
    Scientific Foundation SPIROSKI ; 2019
    In:  Open Access Macedonian Journal of Medical Sciences Vol. 7, No. 2 ( 2019-01-28), p. 259-263
    Details
    In: Open Access Macedonian Journal of Medical Sciences, Scientific Foundation SPIROSKI, Vol. 7, No. 2 ( 2019-01-28), p. 259-263
    Abstract: BACKGROUND: Chronic urticaria, a mast cell-driven condition, is common, debilitating and hard to treat. H1-antihistamines are the first line treatment of chronic urticaria, but often patients do not get satisfactory relief with the recommended dose. European guidelines recommend increased antihistamine doses up to four-fold. AIM: We conducted this study to evaluate the efficacy of increased H1-antihistamine doses up to two-fold in Vietnamese chronic urticaria patients. METHODS: One hundred and two patients with chronic urticaria were recruited for treatment with levocetirizine (n = 52) or fexofenadine (n = 50). Treatment started at the conventional daily dose of 5 mg levocetirizine or 180 mg fexofenadine for 2 weeks and then increased to 10 mg levocetirizine or 360 mg fexofenadine for 2 weeks if patients did not have an improvement in symptoms. At week 0, week 2 and week 4 wheal, pruritus, size of the wheal, total symptom scores, and associated side-effects were assessed. RESULTS: With the conventional dose, the total symptom scores after week 2 decreased significantly in both groups compared to baseline figures, i.e. 7.4 vs 2.3 for levocetirizine group and 8.0 vs 2.6 for fexofenadine group (p 〈 0.05). However, there were still 26 patients in each group who did not have improvements. Of these 26 patients, after having a two-fold increase of the conventional dose, 11.5% and 38.5% became symptom-free at week 4 in levocetirizine group and fexofenadine group, respectively. At week 4 in both groups, the total symptom scores had significantly decreased when compared with those at week 2 (2.8 ± 1.5 versus 4.7 ± 1.6 in levocetirizine group; 2.1 ± 1.9 versus 5.1 ± 1.4 in fexofenadine group). In both groups, there was no difference in the rate of negative side effects between the conventional dose and the double dose. CONCLUSION: This study showed that increasing the dosages of levocetirizine and fexofenadine by two-fold improved chronic urticaria symptoms without increasing the rate of negative side effects.
    Type of Medium: Online Resource
    ISSN: 1857-9655
    URL: Article
    DOI: 10.3889/oamjms.2019.069
    Language: Unknown
    Publisher: Scientific Foundation SPIROSKI
    Publication Date: 2019
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  • 8
    Online Resource
    Online Resource
    Efficacy of Oral Isotretinoin in Combination with Desloratadine in the Treatment of Common Vulgaris Acne in Vietnamese Patients
    Scientific Foundation SPIROSKI ; 2019
    In:  Open Access Macedonian Journal of Medical Sciences Vol. 7, No. 2 ( 2019-01-25), p. 217-220
    Details
    In: Open Access Macedonian Journal of Medical Sciences, Scientific Foundation SPIROSKI, Vol. 7, No. 2 ( 2019-01-25), p. 217-220
    Abstract: AIM: To evaluate the efficacy of oral isotretinoin used alone and in combination with desloratadine in the treatment of moderate acne vulgaris. METHODS: A comparative clinical trial was undertaken to evaluate the efficacy of oral isotretinoin alone and in combination with desloratadine in the treatment of 62 moderate acne vulgaris patients. Patients were randomised into two groups with 31 patients in each group. Each studied group's patient took 20 mg isotretinoin and 5 mg desloratadine per day. In the control group, patients took only 20 mg isotretinoin per day. The treatment time was 16 weeks. The evaluation and follow-up were done at week 2, 4, 8, 12 and 16 of the treatment. RESULTS: The studied group had a better curative rate than the control group (45.2% versus 22.6%). The average number of inflammatory lesions in the studied group was significantly lower than the control group (0.19 versus 0.94). The mean GAGS score of the studied group was significantly lower than the control group (3.71 versus 6.52). Acne outbreaks rate of the studied group was lower than the control group (in week 2: 22.6% versus 45.2% and in week 4: 16.1% versus 38.7%, respectively). The rate of itchy was lower in the studied group. CONCLUSION: In the treatment of moderate acne vulgaris, oral isotretinoin in combination with desloratadine is more effective and has fewer side effects than using isotretinoin alone.
    Type of Medium: Online Resource
    ISSN: 1857-9655
    URL: Article
    DOI: 10.3889/oamjms.2019.054
    Language: Unknown
    Publisher: Scientific Foundation SPIROSKI
    Publication Date: 2019
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  • 9
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    Online Resource
    ĐIỀU TRỊ BỆNH NHÂN PEMPHIGUS TẠI KHOA KHÁM BỆNH, BỆNH VIỆN DA LIỄU TRUNG ƯƠNG TỪ NĂM 2015 ĐẾN NĂM 2021
    Vietnamese Society of Dermatology and Venereology ; 2023
    In:  Tạp chí Da liễu học Việt Nam , No. 38 ( 2023-03-05)
    Details
    In: Tạp chí Da liễu học Việt Nam, Vietnamese Society of Dermatology and Venereology, , No. 38 ( 2023-03-05)
    Abstract: Đặt vấn đề: Pemphigus là nhóm bệnh da bọng nước tự miễn gây ra bởi các tự kháng thể chống lại desmogleins và đặc trưng lâm sàng bởi sự xuất hiện các bọng nước và vết trợt đau ở trên da và niêm mạc. Cho đến nay chưa có thuốc chữa khỏi bệnh hoàn toàn nhưng có nhiều phương pháp giúp kiểm soát bệnh. Mục tiêu: Khảo sát các phương pháp điều trị bệnh pemphigus trên bệnh nhân đến khám tại khoa Khám bệnh, Bệnh viện Da liễu TW từ năm 2015 đến năm 2021. Phương pháp: Nghiên cứu mô tả cắt ngang trên hồ sơ bệnh án của 279 bệnh nhân bị pemphigus điều trị ngoại trú tại tại Khoa khám bệnh của Bệnh viện Da liễu trung ương từ 2015 đến 2021. Kết quả: Hầu hết các bệnh nhân được điều trị chủ yếu bằng corticoid đơn thuần:  65,1% ở tất cả các bệnh nhân pemphigus và 62,8% đến 100% ở các dưới nhóm  pemphigus. Tiếp đến là nhóm bệnh nhân được điều trị bằng corticoid đường toàn thân kết hợp với các thuốc ức chế miễn dịch khác trong đó azathioprine được sử dụng nhiều nhất. Có 1 nhóm nhỏ bệnh nhân đang sử dụng thuốc Đông y để điều trị mặc dù phương pháp này không được khuyến cáo do có ít bằng chứng khoa học. Về hiệu quả, các phương pháp điều trị mà bệnh nhân đã sử dụng đã giúp duy trì bệnh ở mức độ nhẹ và vừa với tỉ lệ từ 75% đến 90%.  Kết luận: Tại khoa Khám bệnh, Bệnh viện Da liễu TW, phần lớn bệnh nhân pemphigus được điều trị bằng corticoid đơn thuần, tiếp đến là bằng corticoid kết hợp với các thuốc ức chế miễn dịch khác trong đó chủ yếu là kết hợp với azathioprine đã giúp phần lớn bệnh nhân duy trì bệnh của mình ở mức nhẹ và trung bình.
    Type of Medium: Online Resource
    ISSN: 1859-4824
    URL: Issue
    URL: Article
    DOI: 10.56320/tcdlhvn.v38i
    DOI: 10.56320/tcdlhvn.38.35
    Language: Unknown
    Publisher: Vietnamese Society of Dermatology and Venereology
    Publication Date: 2023
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  • 10
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    Online Resource
    HIỆU QUẢ CAN THIỆP DINH DƯỠNG THEO CHƯƠNG TRÌNH ERAS TRÊN BỆNH NHÂN CẮT ĐOẠN DẠ DÀY DO UNG THƯ
    Vietnam Medical Journal, Vietnam Medical Association ; 2022
    In:  Tạp chí Y học Việt Nam Vol. 517, No. 1 ( 2022-08-21)
    Details
    In: Tạp chí Y học Việt Nam, Vietnam Medical Journal, Vietnam Medical Association, Vol. 517, No. 1 ( 2022-08-21)
    Abstract: Thực hành nhịn ăn đến khi xuất hiện trung tiện theo quan điểm truyền thống đã được chứng minh không đem lại lợi ích và hiện nay đang dần được thay đổi. Nuôi dưỡng đường miệng sớm sau phẫu thuật được khuyến cáo trong hầu hết hướng dẫn của các Hiệp hội Dinh dưỡng lớn và các chương trình tăng cường hồi phục sau mổ trên thế giới. Chúng tôi tiến hành thử nghiệm lâm sàng có đối chứng trên 42 bệnh nhân cắt đoạn dạ dày do ung thư được chia ngẫu nhiên thành 2 nhóm. Nhóm can thiệp được nuôi dưỡng đường miệng sớm trong vòng 24-48 giờ sau phẫu thuật. Nhóm chứng được nuôi dưỡng theo thực hành thường quy của bệnh viện. Thời điểm khởi động ruột trung bình của nhóm can thiệp và nhóm chứng lần lượt là 35,4±27,9 giờ và 91,5± 29,9 giờ. Kết quả cho thấy nuôi dưỡng đường miệng sớm thúc đẩy sự phục hồi chức năng ruột: Thời điểm xuất hiện nhu động ruột (27,7±14,6 và 39,6±12,7 giờ; p=0,008 ) và trung tiện (51,0 ± 4,9 và 76,6±7,0 giờ) sớm hơn có ý nghĩa thống kê ở nhóm can thiệp so với nhóm chứng (p=0,008 và p=0,0047). Tỷ lệ các triệu chứng tiêu hóa(27,3% và 36,4%) và biến chứng sau phẫu thuật (4,5% và 4,5%), giữa 2 nhóm không có sự khác biệt có ý nghĩa thống kê, không ghi nhận trường hợp nào có rò bục miệng nối. Ngoài ra, nồng độ Prealbumin máu được cải thiện có ý nghĩa thống kê ở nhóm can thiệp (22,5 ± 0,62 và 16,5 ± 0,71 g/l; p=0,0021).
    Type of Medium: Online Resource
    ISSN: 1859-1868
    URL: Article
    DOI: 10.51298/vmj.v517i1.3166
    Language: Unknown
    Publisher: Vietnam Medical Journal, Vietnam Medical Association
    Publication Date: 2022
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