In:
Chirality, Wiley, Vol. 20, No. 2 ( 2008-02), p. 115-118
Abstract:
Candida rugosa lipase‐catalysed hydrolysis of three different 2‐substituted‐aryloxyacetic esters was performed in aqueous buffer containing dimethyl sulphoxide and isopropanol from 0 to 80% v/v as additives, in order to obtain an enhancement of the enantioselectivity. For 2‐( p ‐chlorophenoxy)acetic acid and 2‐ n ‐butyl‐2‐( p ‐chlorophenoxy)acetic acid ethyl esters, DMSO enhanced enzyme enantioselectivity more than IPA with an opposite enzymatic enantiopreference. The cosolvents moderately improved Candida rugosa lipase enantioselectivity for 2‐phenyl‐2‐( p ‐chlorophenoxy)acetic acid ethyl ester. Chirality, 2008. © 2007 Wiley‐Liss, Inc.
Type of Medium:
Online Resource
ISSN:
0899-0042
,
1520-636X
Language:
English
Publisher:
Wiley
Publication Date:
2008
detail.hit.zdb_id:
1011639-4
detail.hit.zdb_id:
2001237-8
SSG:
12
SSG:
15,3
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