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  • 1
    In: Journal of Neurology & Stroke, MedCrave Group Kft., Vol. 9, No. 3 ( 2019-6-3)
    Type of Medium: Online Resource
    ISSN: 2373-6410
    URL: Issue
    Language: Unknown
    Publisher: MedCrave Group Kft.
    Publication Date: 2019
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  • 2
    In: Surgical Neurology International, Scientific Scholar, Vol. 11 ( 2020-03-06), p. 42-
    Abstract: The standard of care is to utilize intraoperative neurophysiological monitoring (IOM) of triggered electromyography (tEMG) during posterior lumbosacral instrumented-fusion surgery. IOM should theoretically signal misplacement of S1 screws into the neural L5–S1 foramen or spinal canal, utilizing screw stimulation, and recording of the lower limb muscles and the anal sphincter. Here, we evaluated when and whether anterolateral S1 screw malposition could be detected by IOM/tEMG during open posterior lumbosacral instrumented fusion surgery. Methods: tEMG, somatosensory-evoked potential (SSEP), and transcranial electrical motor-evoked potential (TcMEP) data were retrospectively reviewed from 2015 to 2017 during open posterior lumbosacral instrumented fusions. We utilized screw stimulation alert thresholds of 〈 14 mA (tEMG) and recorded from the lower extremity muscles and anal sphincter. Furthermore, all patients underwent routine postoperative computed tomography (CT) scans to confirm the screw location. Results: There were 106 S1 screws placed in 54 patients: 52 bilateral and 2 unilateral. In 6 patients (11.1%), 7 screws (6.6%) registered at low tEMG thresholds. In 1 patient, the postoperative CT scan documented external malposition of the screw despite no intraoperative IOM/tEMG alert. When S1 misplaced screws were stimulated, the most sensitive muscle was the tibialis anterior; the sensitivity of the IOM/tEMG was 87.5%, the specificity was 97.9%, the positive predictive value was 77.8%, and the negative predictive value was 98.9%. TcMEP and SSEP did not change during any of the operations. Notably, no patient developed a new neurological deficit. Conclusion: Anterolateral S1 screw malposition can be detected accurately utilizing IOM/tEMG stimulation of screws. When alerts occur, they can largely be corrected by partially backing out the screw (e.g., a few turns) and/ or changing the screw trajectory.
    Type of Medium: Online Resource
    ISSN: 2152-7806
    Language: English
    Publisher: Scientific Scholar
    Publication Date: 2020
    detail.hit.zdb_id: 2567759-7
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  • 3
    Online Resource
    Online Resource
    Journal of Neurosurgery Publishing Group (JNSPG) ; 1991
    In:  Journal of Neurosurgery Vol. 75, No. 2 ( 1991-08), p. 299-304
    In: Journal of Neurosurgery, Journal of Neurosurgery Publishing Group (JNSPG), Vol. 75, No. 2 ( 1991-08), p. 299-304
    Abstract: ✓ The foramen caecum (FC) is a triangular-shaped fossa situated in the midline on the base of the brain stem, at the pontomedullary junction. Although this area is known to have a very high concentration of brainstem perforating vessels, its microvascular anatomy has not been studied in detail. The purpose of this study was to detail the microvasculature of this territory. Twenty unfixed brains were injected with silicone rubber solution and dissected under a microscope equipped with a camera. The origin, course, outer diameter, and branching pattern of the perforators were examined. The total number of perforators found in the 20 brains was 287, with an average (± standard deviation) of 14.35 ± 1.24 perforators per brain (range seven to 28). Their origin was as follows: right vertebral artery in 52 perforators (18.11%); left vertebral artery in 35 (12.19%); basilar artery below the anterior inferior cerebellar artery (AICA) in 139 (48.43%); basilar artery above the AICA in 46 (16.02%); AICA in 10 (3.48%); and anterior spinal artery in five (1.74%). Most of the perforators arose as sub-branches of larger trunks; their average outer diameter was 0.16 ± 0.006 mm while that of trunks was 0.35 ± 0.02 mm. These anatomical data are important for those wishing 1) to study the pathophysiology of vascular insults to this area caused by atheromas, thrombi, and emboli; 2) to plan vertebrobasilar aneurysm surgery; 3) to plan surgery for vertebrobasilar insufficiency; and 4) to study foramen magnum neoplasms.
    Type of Medium: Online Resource
    ISSN: 0022-3085
    RVK:
    RVK:
    Language: Unknown
    Publisher: Journal of Neurosurgery Publishing Group (JNSPG)
    Publication Date: 1991
    detail.hit.zdb_id: 2026156-1
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  • 4
    In: Global Spine Journal, SAGE Publications, Vol. 5, No. 1_suppl ( 2015-05), p. s-0035-1554449-s-0035-1554449
    Abstract: Thoracic pedicle screws placement remains being a challenge despite modern technologies available. To assess neural integrity during these surgeries, intraoperative neurophysiological monitoring (IOM) is indicated. Motor-evoked potentials (MEP) and somatosensory-evoked potentials (SSEP) give valuable information regarding spinal cord function, and pedicle screws stimulation could evaluate medial malpositioning. However, the accuracy of thoracic pedicle screws stimulation is still controversial, using single-pulse stimulation, recording from intercostal and abdominal muscles, and with high false-positive rate. Objective This article aims to demonstrate the superiority of a recently validated IOM method by Blair Calancie, and share our experience with it. Material and Methods Prospective collected and reviewed study since March to October 2014. During T1–T12 level surgeries, we stimulated medial wall of pedicle track before screw placement with a ball-tipped probe using pulse-train stimulation, and recording from lower limbs muscles. MEP and SSEP were performed, and a postoperative computed tomography (CT) scans in all the cases. Results In 21 patients, 240 thoracic pedicle screws were analyzed. In 36 screws of them (17.6%), a medial pedicle breach was informed, and 19 of 36 were redirected correctly more lateral; 8 of 36 pedicles were skipped; and 7 of 36 screws were placed regardless IOM warning criteria (3.4%), with a CT scan confirming medial misplacement  〉  2 mm. Fluoroscopy and manual pedicle palpation evinced a medial breach in 3 of 36 and 1 of 36 trajectories, respectively, but after pedicle track stimulation was done and informed. We did not observe any MEP or SSEP change during all these screws. Fortunately, no patients developed a new neurological deficit. CSF leak was not reported in this series. Our sensitivity with this method was 93.9%, specificity 97.6%, positive predictive value 86.1%, and negative predictive value was 99.0%. Conclusion Pulse-train stimulation of pedicle track before screw placement has huge superiority over traditional IOM techniques, avoiding spinal cord encroachment and new neurological deficit. This IOM method is highly accurate during thoracic pedicle screws placement.
    Type of Medium: Online Resource
    ISSN: 2192-5682 , 2192-5690
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 2648287-3
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  • 5
    Online Resource
    Online Resource
    Informa UK Limited ; 1992
    In:  Neurological Research Vol. 14, No. 3 ( 1992-06), p. 259-262
    In: Neurological Research, Informa UK Limited, Vol. 14, No. 3 ( 1992-06), p. 259-262
    Type of Medium: Online Resource
    ISSN: 0161-6412 , 1743-1328
    RVK:
    Language: English
    Publisher: Informa UK Limited
    Publication Date: 1992
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