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  • 1
    In: Chest, Elsevier BV, Vol. 148, No. 1 ( 2015-07), p. 202-210
    Type of Medium: Online Resource
    ISSN: 0012-3692
    RVK:
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2015
    detail.hit.zdb_id: 2007244-2
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  • 2
    In: European Journal of Heart Failure, Wiley, Vol. 21, No. 6 ( 2019-06), p. 754-766
    Abstract: Although acute decompensated heart failure (ADHF) is a common cause of dyspnoea, its diagnosis still represents a challenge. Lung ultrasound (LUS) is an emerging point‐of‐care diagnostic tool, but its diagnostic performance for ADHF has not been evaluated in randomized studies. We evaluated, in patients with acute dyspnoea, accuracy and clinical usefulness of combining LUS with clinical assessment compared to the use of chest radiography (CXR) and N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP) in conjunction with clinical evaluation. Methods and results This was a randomized trial conducted in two emergency departments. After initial clinical evaluation, patients with acute dyspnoea were classified by the treating physician according to presumptive aetiology (ADHF or non‐ADHF). Patients were subsequently randomized to continue with either LUS or CXR/NT‐proBNP. A new diagnosis, integrating the results of both initial assessment and the newly obtained findings, was then recorded. Diagnostic accuracy and clinical usefulness of LUS and CXR/NT‐proBNP approaches were calculated. A total of 518 patients were randomized. Addition of LUS had higher accuracy [area under the receiver operating characteristic curve (AUC) 0.95] than clinical evaluation alone (AUC 0.88) in identifying ADHF ( P   〈  0.01). In contrast, use of CXR/NT‐proBNP did not significantly increase the accuracy of clinical evaluation alone (AUC 0.87 and 0.85, respectively; P   〉  0.05). The diagnostic accuracy of the LUS‐integrated approach was higher then that of the CXR/Nt‐proBNP‐integrated approach (AUC 0.95 vs. 0.87, p  〈  0.01). Combining LUS with the clinical evaluation reduced diagnostic errors by 7.98 cases/100 patients, as compared to 2.42 cases/100 patients in the CXR/Nt‐proBNP group. Conclusion Integration of LUS with clinical assessment for the diagnosis of ADHF in the emergency department seems to be more accurate than the current diagnostic approach based on CXR and NT‐proBNP.
    Type of Medium: Online Resource
    ISSN: 1388-9842 , 1879-0844
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2019
    detail.hit.zdb_id: 1500332-2
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  • 3
    Online Resource
    Online Resource
    Springer Science and Business Media LLC ; 2022
    In:  Scientific Reports Vol. 12, No. 1 ( 2022-11-18)
    In: Scientific Reports, Springer Science and Business Media LLC, Vol. 12, No. 1 ( 2022-11-18)
    Abstract: The contrasting dynamics between Mauna Loa and Kīlauea have been studied over the last 100 years from multiple viewpoints. The fact that dynamic changes of one volcano trigger a dynamic response of the other volcano indicates a connection may exist. Petrological works show a direct relationship between the magmatic systems of these two volcanoes is not possible. We analysed DInSAR data and GPS measurements of ground deformation patterns associated with the activity of Mauna Loa and Kīlauea volcanoes. The DInSAR SBAS dataset spans the interval between 2003 and 2010, and was acquired along ascending and descending orbits of the ENVISAT (ESA) satellite under different look angles. Of the 10 tracks that cover the Big Island (Hawai‘i), 4 cover both volcanic edifices. Using GPS measurements, we computed the areal strain on 15 triplets of stations for Kīlauea volcano and 11 for Mauna Loa volcano. DInSAR data was analysed by applying Independent Component Analysis (ICA) to decompose the time-varying ground deformation pattern of both volcanoes. The results revealed anticorrelated ground deformation behaviour of the main calderas of Mauna Loa and Kīlauea, meaning that the opposite response is seen in the ground deformation of one volcano with respect to the other. At the same time, Kīlauea exhibits a more complex pattern, with an additional component, which appears not to be correlated with the dynamics of Mauna Loa. The GPS areal strain time series support these findings. To corroborate and help interpret the results, we performed inverse modelling of the observed ground deformation pattern using analytical source models. The results indicate that the ground deformation of Mauna Loa is associated with a dike-shaped source located at 6.2 km depth. In comparison, the anticorrelated ground deformation of Kīlauea is associated with a volumetric source at 1.2 km depth. This excludes a hydraulic connection as a possible mechanism to explain the anticorrelated behaviour; instead, we postulate a stress-transfer mechanism. To support this hypothesis, we performed a 3D numerical modelling of stress and strain fields in the study area, determining the elastic interaction of each source over the others. The most relevant finding is that the Mauna Loa shallow plumbing system can affect the shallowest magmatic reservoir of Kīlauea, while the opposite scenario is unlikely. Conversely, the second independent component observed at Kīlauea is associated to a sill-shaped source located at a depth of 3.5 km, which is less affected by this interaction process.
    Type of Medium: Online Resource
    ISSN: 2045-2322
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2022
    detail.hit.zdb_id: 2615211-3
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  • 4
    In: Remote Sensing, MDPI AG, Vol. 14, No. 21 ( 2022-10-25), p. 5328-
    Abstract: In this study, we describe new advances in the multiscale methodology to allow a more realistic interpretation of volcanic deformation fields by investigating geometrically irregular bodies and multi-source scenarios. We propose an integrated approach to be applied to InSAR measurements, employing the Multiridge and ScalFun methods and the Total Horizontal Derivative (THD) technique: this strategy provides unconstrained information on the source geometrical parameters, such as the depth, position, shape, and horizontal extent. To do this, we start from conditions where the biharmonic deformation field satisfies Laplace’s equation and homogeneity law. We test the use of the multiscale procedures to model single and multisource scenarios with irregular geometries by retrieving satisfactory results for a set of simulated sources. Finally, we employ the proposed approach to the 2004–2009 uplift episode at the Yellowstone Caldera (U.S.) measured by ENVISAT InSAR to provide information about the volcanic plumbing system. Our results indicate a single ~50×20 km2 extended source lying beneath the caldera at around 10 km b.s.l. (depth to the center), which is shallower below both the resurgent domes (6–7 km b.s.l. depth to the top).
    Type of Medium: Online Resource
    ISSN: 2072-4292
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2513863-7
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  • 5
    In: BMC Infectious Diseases, Springer Science and Business Media LLC, Vol. 23, No. 1 ( 2023-04-26)
    Abstract: Most countries have enacted some restrictions to reduce social contacts to slow down disease transmission during the COVID-19 pandemic. For nearly two years, individuals likely also adopted new behaviours to avoid pathogen exposure based on personal circumstances. We aimed to understand the way in which different factors affect social contacts – a critical step to improving future pandemic responses. Methods The analysis was based on repeated cross-sectional contact survey data collected in a standardized international study from 21 European countries between March 2020 and March 2022. We calculated the mean daily contacts reported using a clustered bootstrap by country and by settings (at home, at work, or in other settings). Where data were available, contact rates during the study period were compared with rates recorded prior to the pandemic. We fitted censored individual-level generalized additive mixed models to examine the effects of various factors on the number of social contacts. Results The survey recorded 463,336 observations from 96,456 participants. In all countries where comparison data were available, contact rates over the previous two years were substantially lower than those seen prior to the pandemic (approximately from over 10 to  〈  5), predominantly due to fewer contacts outside the home. Government restrictions imposed immediate effect on contacts, and these effects lingered after the restrictions were lifted. Across countries, the relationships between national policy, individual perceptions, or personal circumstances determining contacts varied. Conclusions Our study, coordinated at the regional level, provides important insights into the understanding of the factors associated with social contacts to support future infectious disease outbreak responses.
    Type of Medium: Online Resource
    ISSN: 1471-2334
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
    detail.hit.zdb_id: 2041550-3
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  • 6
    In: Scientific Reports, Springer Science and Business Media LLC, Vol. 5, No. 1 ( 2015-08-17)
    Abstract: We found the first evidence, in the last 30 years, of a renewed magmatic activity at Campi Flegrei caldera from January 2012 to June 2013. The ground deformation, observed through satellite interferometry and GPS measurements, have been interpreted as the effect of the intrusion at shallow depth (3090 ± 138 m) of 0.0042 ± 0.0002 km 3 of magma within a sill. This interrupts about 28 years of dominant hydrothermal activity and occurs in the context of an unrest phase which began in 2005 and within a more general ground uplift that goes on since 1950. This discovery has implications on the evaluation of the volcanic risk and in the volcanic surveillance of this densely populated area.
    Type of Medium: Online Resource
    ISSN: 2045-2322
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2015
    detail.hit.zdb_id: 2615211-3
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  • 7
    In: Journal of Geophysical Research: Solid Earth, American Geophysical Union (AGU), Vol. 118, No. 8 ( 2013-08), p. 4361-4377
    Abstract: Inverse modeling method for source temporal evolution combining data sets Active crustal magmatic system with two levels during El Hierro eruption Depth of crustal magmatic chambers depends on lithosphere thermomechanics
    Type of Medium: Online Resource
    ISSN: 2169-9313 , 2169-9356
    URL: Issue
    Language: English
    Publisher: American Geophysical Union (AGU)
    Publication Date: 2013
    detail.hit.zdb_id: 2016813-5
    detail.hit.zdb_id: 161666-3
    detail.hit.zdb_id: 3094197-0
    SSG: 16,13
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  • 8
    In: BMC Public Health, Springer Science and Business Media LLC, Vol. 23, No. 1 ( 2023-05-19)
    Abstract: Most countries around the world enforced non-pharmaceutical interventions against COVID-19. Italy was one of the first countries to be affected by the pandemic, imposing a hard lockdown, in the first epidemic wave. During the second wave, the country implemented progressively restrictive tiers at the regional level according to weekly epidemiological risk assessments. This paper quantifies the impact of these restrictions on contacts and on the reproduction number. Methods Representative (with respect to age, sex, and region of residence) longitudinal surveys of the Italian population were undertaken during the second epidemic wave. Epidemiologically relevant contact patterns were measured and compared with pre-pandemic levels and according to the level of interventions experienced by the participants. Contact matrices were used to quantify the reduction in the number of contacts by age group and contact setting. The reproduction number was estimated to evaluate the impact of restrictions on the spread of COVID-19. Results The comparison with the pre-pandemic baseline shows a significant decrease in the number of contacts, independently from the age group or contact settings. This decrease in the number of contacts significantly depends on the strictness of the non-pharmaceutical interventions. For all levels of strictness considered, the reduction in social mixing results in a reproduction number smaller than one. In particular, the impact of the restriction on the number of contacts decreases with the severity of the interventions. Conclusions The progressive restriction tiers implemented in Italy reduced the reproduction number, with stricter interventions associated with higher reductions. Readily collected contact data can inform the implementation of mitigation measures at the national level in epidemic emergencies to come.
    Type of Medium: Online Resource
    ISSN: 1471-2458
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
    detail.hit.zdb_id: 2041338-5
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  • 9
    Online Resource
    Online Resource
    MDPI AG ; 2019
    In:  Remote Sensing Vol. 11, No. 6 ( 2019-03-23), p. 703-
    In: Remote Sensing, MDPI AG, Vol. 11, No. 6 ( 2019-03-23), p. 703-
    Abstract: Uturuncu volcano (southwestern Bolivia) is localized within one of the largest updoming volcanic zones, the Altiplano Puna Volcanic Complex (APVC). In several geodetic studies the observed uplift phenomenon is analyzed and modeled by considering a deep source, related to the Altiplano Puna Magma Body (APMB). In this framework, we perform a multiscale analysis on the 2003–2010 ENVISAT satellite data to investigate the existence of a multi-source scenario for this region. The proposed analysis is based on Cross-correlation and Multiridge method, pointing out the spatial and temporal multiscale properties of the deformation field. In particular, we analyze the vertical component of ground deformation during two time interval: within the 2005–2008 time interval an inflating source at 18.7 km depth beneath the central zone of the APVC is retrieved; this result is in good agreement with those proposed by several authors for the APMB. Between August 2006 and February 2007, we identify a further inflating source at 4.5 km depth, beneath Uturuncu volcano; the existence of this latter, located just below the 2009–2010 seismic swarm, is supported by petrological, geochemical, and geophysical evidence, indicating as a possible interpretative scenario the action of shallow, temporarily trapped fluids.
    Type of Medium: Online Resource
    ISSN: 2072-4292
    Language: English
    Publisher: MDPI AG
    Publication Date: 2019
    detail.hit.zdb_id: 2513863-7
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  • 10
    Online Resource
    Online Resource
    MDPI AG ; 2021
    In:  Remote Sensing Vol. 13, No. 12 ( 2021-06-11), p. 2298-
    In: Remote Sensing, MDPI AG, Vol. 13, No. 12 ( 2021-06-11), p. 2298-
    Abstract: In this study, we analyze the 2009–2013 uplift phenomenon at Campi Flegrei (CF) caldera in terms of temporal and spatial variations in the stress/strain field due to the effect of an inflating source. We start by performing a 3D stationary finite element (FE) modeling of X-band COSMO-SkyMed DInSAR and GPS mean velocities to retrieve the geometry and location of the deformation source. The modeling results suggest that the best-fit source is a three-axis oblate spheroid ~3 km deep, which is mostly elongated in the NE–SW direction. Furthermore, we verify the reliability of model results by calculating the total horizontal derivative (THD) of the modeled vertical velocity component; the findings emphasize that the THD maxima overlap with the projection of source boundaries at the surface. Then, we generate a 3D time-dependent FE model, comparing the spatial and temporal distribution of the shear stress and volumetric strain with the seismic swarms beneath the caldera. We found that low values of shear stress are observed corresponding with the shallow hydrothermal system where low-magnitude earthquakes occur, whereas high values of shear stress are found at depths of about 3 km, where high-magnitude earthquakes nucleate. Finally, the volumetric strain analysis highlights that the seismicity occurs mainly at the border between compression and dilatation modeled regions, and some seismic events occur within compression regions.
    Type of Medium: Online Resource
    ISSN: 2072-4292
    Language: English
    Publisher: MDPI AG
    Publication Date: 2021
    detail.hit.zdb_id: 2513863-7
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