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  • 1
    Online Resource
    Online Resource
    Survival of breast cancer patients in rural Ethiopia
    Springer Science and Business Media LLC ; 2018
    In:  Breast Cancer Research and Treatment Vol. 170, No. 1 ( 2018-7), p. 111-118
    Details
    In: Breast Cancer Research and Treatment, Springer Science and Business Media LLC, Vol. 170, No. 1 ( 2018-7), p. 111-118
    Type of Medium: Online Resource
    ISSN: 0167-6806 , 1573-7217
    URL: Article
    DOI: 10.1007/s10549-018-4724-z
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2018
    detail.hit.zdb_id: 2004077-5
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  • 2
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    Breast Nurse Intervention to Improve Adherence to Endocrine Therapy Among Breast Cancer Patients in South Ethiopia
    Oxford University Press (OUP) ; 2022
    In:  The Oncologist Vol. 27, No. 8 ( 2022-08-05), p. e650-e660
    Details
    In: The Oncologist, Oxford University Press (OUP), Vol. 27, No. 8 ( 2022-08-05), p. e650-e660
    Abstract: Many women in rural Ethiopia do not receive adjuvant therapy following breast cancer surgery despite the majority being diagnosed with estrogen-receptor-positive breast cancer and tamoxifen being available in the country. We aimed to compare a breast nurse intervention to improve adherence to tamoxifen therapy for breast cancer patients. Methods and Materials The 8 hospitals were randomized to intervention and control sites. Between February 2018 and December 2019, patients with breast cancer were recruited after their initial surgery. The primary outcome of the study was adherence to tamoxifen therapy by evaluating 12-month medication-refill data with medication possession ratio (MPR) and using a simplified medication adherence scale (SMAQ) in a subjective assessment. Results A total of 162 patients were recruited (87 intervention and 75 control). Trained nurses delivered education and provided literacy material, gave additional empathetic counselling, phone call reminders, and monitoring of medication refill at the intervention hospitals. Adherence according to MPR at 12 months was high in both the intervention (90%) and control sites (79.3%) (P = .302). The SMAQ revealed that adherence at intervention sites was 70% compared with 44.8% in the control sites (P = .036) at 12 months. Persistence to therapy was found to be 91.2% in the intervention and 77.8% in the control sites during the one-year period (P = .010). Conclusion Breast nurses can improve cost-effective endocrine therapy adherence at peripheral hospitals in low-resource settings. We recommend such task sharing to overcome the shortage of oncologists and distances to central cancer centers.
    Type of Medium: Online Resource
    ISSN: 1083-7159 , 1549-490X
    URL: Article
    DOI: 10.1093/oncolo/oyac081
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2022
    detail.hit.zdb_id: 2023829-0
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  • 3
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    Online Resource
    Breast Health Global Initiative Recommended Breast Cancer Prevention and Care in Rural Ethiopia
    American Society of Clinical Oncology (ASCO) ; 2018
    In:  Journal of Global Oncology Vol. 4, No. Supplement 3 ( 2018-10), p. 1s-1s
    Details
    In: Journal of Global Oncology, American Society of Clinical Oncology (ASCO), Vol. 4, No. Supplement 3 ( 2018-10), p. 1s-1s
    Abstract: Breast cancer is the most common cancer among women worldwide and is the leading cause of cancer death among women in low- and middle-income countries, including Ethiopia. Availability of both basic and comprehensive services in all frontline health care facilities is important for cancer control. Whereas women are equally affected in both urban and rural settings, most services are present in urban areas. We assessed health system readiness for breast cancer prevention and treatment in selected hospitals in Western Ethiopia. Methods A total of seven rural hospitals in Western Ethiopia were assessed for availability of comprehensive breast cancer services. A checklist prepared on the basis of breast care prevention and control standards for low-resource settings—recommended by the 2007 Global Summit of Breast Health Global Initiative—was used for the assessment. Data were descriptively analyzed and discussed. Results Whereas cancer incidence and mortality rates are increasing in Ethiopia and other sub-Saharan countries, there is currently no competent health system available that is adequately equipped to meet this challenge. In Ethiopia, the majority of systemic oncologic treatment is administered at the Addis Ababa University Hospital in the capital city, and the majority of patients are referred to this center, which, for the average patient, is more than 500 km away. There are relatively large numbers of health professionals in health facilities in Western Ethiopia, but a critical absence of pathologists and oncologists. Basic diagnostic services, such as ultrasonography and X-ray, were found to be available in most hospitals; however, there were major gaps in cytologic and pathologic services. The nearest referral centers for pathology and additional breast cancer treatment required travelling significant distances; there were no systemic breast cancer treatment and palliative services available in Western Ethiopia. Conclusion Our study revealed that all health facilities lack a comprehensive package of breast cancer diagnosis and treatment services. The lack of implemented comprehensive breast care prevention, diagnosis, treatment, and referral services is representative of most other rural settings in Ethiopia. This calls for a nationally coordinated effort in defining and implementing breast cancer prevention and control standards to realize the national cancer control plan. AUTHORS' DISCLOSURES OF POTENTIAL CONFLICTS OF INTEREST The following represents disclosure information provided by authors of this manuscript. All relationships are considered compensated. Relationships are self-held unless noted. I = Immediate Family Member, Inst = My Institution. Relationships may not relate to the subject matter of this manuscript. For more information about ASCO's conflict of interest policy, please refer to www.asco.org/rwc or ascopubs.org/jco/site/ifc . Eva Kantelhardt Travel, Accommodations, Expenses: Daiichi Sankyo Oncology Europe
    Type of Medium: Online Resource
    ISSN: 2378-9506
    URL: Article
    DOI: 10.1200/JGO.18.99800
    Language: English
    Publisher: American Society of Clinical Oncology (ASCO)
    Publication Date: 2018
    detail.hit.zdb_id: 3018917-2
    detail.hit.zdb_id: 2840981-4
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  • 4
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    Knowledge, attitude, and practice of health professionals in Ethiopia toward COVID-19 prevention at early phase
    SAGE Publications ; 2021
    In:  SAGE Open Medicine Vol. 9 ( 2021-01), p. 205031212110122-
    Details
    In: SAGE Open Medicine, SAGE Publications, Vol. 9 ( 2021-01), p. 205031212110122-
    Abstract: Coronavirus disease (COVID-19) is a potentially lethal disease having significant public health concerns. As the disease is new, nothing has been intervened yet. Therefore, here we show the health worker’s knowledge, attitude, and practice toward COVID-19. Methods: The online cross-sectional study design was conducted from April to May 2020, among Ethiopia health workers. The data were collected online, downloaded by an Excel sheet, and transferred to IBM SPSS version 24. Using questionnaire containing four parts sociodemographic, knowledge, attitude, and practice assessing. Linear logistic regression and binary logistic regression were performed to test the association between the dependent and the independent variables. We reported the 95% confidence intervals of adjusted odds ratios with a statistical significance level at less than 0.05 p-values. Results and conclusion: A total of 441 health workers were included in this study. The majority of participants were from urban (88.7%), nurses (53.1%), male (88.4%), and have a degree educational level (66.7%). The mean knowledge level of respondents was 10.13 ± 0.057 standard deviation. The majority of respondents had a positive attitude toward control of COVID-19, 88%, and 77% of respondents had confidence that Ethiopia will control COVID-19. Similarly, male (2.746, 95% confidence interval (1.23, 6.02)) and good knowledge level (1.98, 95% confidence interval (1.01, 3.09)) were found to be a determinant for attitude regarding control of COVID-19. Good knowledge level 1.6 (1.02, 2.6), male sex 2.2 (1.07, 4.6), masters 2.33 (1.06, 5.08), and medical doctors 5.99 (1.76, 20.4) to practice wearing a mask when going out of the home. Knowledge, attitude, and practice of the participant health workers are considerable, but may not be enough to control the disease. Sex, age, and profession of the health workers were determinant factors for knowledge about COVID-19. Therefore, training has to be considered for updating health care workers on COVID-19 prevention and controlled at the national level.
    Type of Medium: Online Resource
    ISSN: 2050-3121 , 2050-3121
    URL: Article
    DOI: 10.1177/20503121211012220
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2735399-0
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  • 5
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    Adherence to Newly Implemented Tamoxifen Therapy for Breast Cancer Patients in Rural Western Ethiopia
    S. Karger AG ; 2021
    In:  Breast Care Vol. 16, No. 5 ( 2021), p. 484-490
    Details
    In: Breast Care, S. Karger AG, Vol. 16, No. 5 ( 2021), p. 484-490
    Abstract: 〈 b 〉 〈 i 〉 Introduction: 〈 /i 〉 〈 /b 〉 Endocrine therapy for breast cancer (BC) patients is highly underutilized in rural Ethiopia and other African countries. 〈 b 〉 〈 i 〉 Objective: 〈 /i 〉 〈 /b 〉 This study aims to assess the feasibility of and adherence to tamoxifen therapy in rural Ethiopia. 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 We ascertained the hormone receptor (HR) status in 101 women diagnosed with BC from January 2010 to December 2015 and who had surgery in Aira Hospital, in rural Ethiopia. From 2013, tamoxifen was offered to patients with HR-positive (HR+) tumors. Prescription refill records and a structured questionnaire were used to assess receipt of and adherence to tamoxifen. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 Of the 101 BC patients tested for HR status during the study period, 66 (65%) patients were HR+ and were eligible for tamoxifen treatment. However, 15 of the HR+ patients died before tamoxifen became available in 2013. Of the remaining 51 HR+ patients, 26 (51%) initiated tamoxifen but only 9 of them (35%) adhered to therapy (medication possession rate ≥80%, median observation 16.2 months). After 1 year, 52% of the patients were still adherent, and 9 patients had discontinued therapy. The reasons for non-initiation of tamoxifen included patient factors ( 〈 i 〉 n 〈 /i 〉 = 5), including financial hardship or lack of transportation, and health care provider factors ( 〈 i 〉 n 〈 /i 〉 = 12). 〈 b 〉 〈 i 〉 Conclusions: 〈 /i 〉 〈 /b 〉 Endocrine therapy for BC patients seems feasible in rural Western Ethiopia, although non-adherence due to financial hardship and a less developed health care infrastructure remains a major challenge. We postulate that the implementation of breast nurses could reduce patient and health system barriers and improve initiation of and adherence to endocrine treatment.
    Type of Medium: Online Resource
    ISSN: 1661-3791 , 1661-3805
    URL: Article
    DOI: 10.1159/000512840
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2021
    detail.hit.zdb_id: 2205941-6
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  • 6
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    〈p〉Knowledge and Attitude Towards Antimicrobial Resistance of Graduating Health Science Students of Wollega University〈/p〉
    Informa UK Limited ; 2020
    In:  Infection and Drug Resistance Vol. Volume 13 ( 2020-11), p. 3937-3944
    Details
    In: Infection and Drug Resistance, Informa UK Limited, Vol. Volume 13 ( 2020-11), p. 3937-3944
    Type of Medium: Online Resource
    ISSN: 1178-6973
    URL: Article
    DOI: 10.2147/IDR.S264481
    Language: English
    Publisher: Informa UK Limited
    Publication Date: 2020
    detail.hit.zdb_id: 2494856-1
    SSG: 15,3
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