In:
International Journal of Rheumatic Diseases, Wiley, Vol. 21, No. 11 ( 2018-11), p. 2019-2027
Abstract:
To study the prevalence and the associated factors of work disability ( WD ) in systemic lupus erythematosus ( SLE ) patients. Methods A sample of 419 SLE patients from an observational cross‐sectional multicenter study was included. Sociodemographic features, disease characteristics, comorbidities, quality of life, unhealthy behaviors, and work‐related factors were measured in a standardized interview. Work disability was defined by patient self‐report of not being able to work because of SLE . To identify variables associated with work disability, two different multivariate regression models using a stepwise backward method were performed. Results Prevalence of WD due to SLE was 24.3%. Eighty‐nine percent were female and 51% were Caucasians. Mean disease duration was 8.9 ± 7.2 years, and median System Lupus International Collaborating Clinics/American College of Rheumatology damage index SLICC ‐ SDI was 1.5 (range 0–17). In stepwise multivariate logistic regression, living below the poverty line (odds ratio [ OR ] = 4.65), less than 12 years of education ( OR = 2.84), Mestizo ethnicity ( OR = 1.94) and SLICC ‐ SDI ( OR = 1.25) were predictors of WD . A second model was performed including patient‐derived measures; in this model sedentary lifestyle ( OR = 2.69) and lower emotional health domain score of the Lupus Quality of Life (LupusQoL) questionnaire ( OR = 1.03) were found to be associated to WD and a higher score in LupusQoL physical health domain ( OR = 0.93) was protective. Conclusion The prevalence of WD in Argentinian SLE patients was 24.3%. WD was associated with ethnic (Mestizo), socioeconomic (poverty) and disease‐related factors. Patient‐related outcomes such us sedentary lifestyle and poor emotional quality of life were also associated with WD .
Type of Medium:
Online Resource
ISSN:
1756-1841
,
1756-185X
DOI:
10.1111/apl.2018.21.issue-11
DOI:
10.1111/1756-185X.13269
Language:
English
Publisher:
Wiley
Publication Date:
2018
detail.hit.zdb_id:
2427877-4
Permalink