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  • 1
    Online-Ressource
    Online-Ressource
    Elsevier BV ; 2019
    In:  The Journal of Emergency Medicine Vol. 56, No. 1 ( 2019-01), p. e1-e4
    In: The Journal of Emergency Medicine, Elsevier BV, Vol. 56, No. 1 ( 2019-01), p. e1-e4
    Materialart: Online-Ressource
    ISSN: 0736-4679
    Sprache: Englisch
    Verlag: Elsevier BV
    Publikationsdatum: 2019
    ZDB Id: 2006769-0
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 2
    Online-Ressource
    Online-Ressource
    Ovid Technologies (Wolters Kluwer Health) ; 2019
    In:  Critical Care Medicine Vol. 47 ( 2019-01), p. 583-
    In: Critical Care Medicine, Ovid Technologies (Wolters Kluwer Health), Vol. 47 ( 2019-01), p. 583-
    Materialart: Online-Ressource
    ISSN: 0090-3493
    Sprache: Englisch
    Verlag: Ovid Technologies (Wolters Kluwer Health)
    Publikationsdatum: 2019
    ZDB Id: 2034247-0
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 3
    Online-Ressource
    Online-Ressource
    Ovid Technologies (Wolters Kluwer Health) ; 2014
    In:  Critical Care Medicine Vol. 42 ( 2014-12), p. A1432-
    In: Critical Care Medicine, Ovid Technologies (Wolters Kluwer Health), Vol. 42 ( 2014-12), p. A1432-
    Materialart: Online-Ressource
    ISSN: 0090-3493
    Sprache: Englisch
    Verlag: Ovid Technologies (Wolters Kluwer Health)
    Publikationsdatum: 2014
    ZDB Id: 2034247-0
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 4
    Online-Ressource
    Online-Ressource
    Ovid Technologies (Wolters Kluwer Health) ; 2019
    In:  Critical Care Medicine Vol. 47 ( 2019-01), p. 597-
    In: Critical Care Medicine, Ovid Technologies (Wolters Kluwer Health), Vol. 47 ( 2019-01), p. 597-
    Materialart: Online-Ressource
    ISSN: 0090-3493
    Sprache: Englisch
    Verlag: Ovid Technologies (Wolters Kluwer Health)
    Publikationsdatum: 2019
    ZDB Id: 2034247-0
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 5
    Online-Ressource
    Online-Ressource
    Ovid Technologies (Wolters Kluwer Health) ; 2014
    In:  Critical Care Medicine Vol. 42 ( 2014-12), p. A1521-
    In: Critical Care Medicine, Ovid Technologies (Wolters Kluwer Health), Vol. 42 ( 2014-12), p. A1521-
    Materialart: Online-Ressource
    ISSN: 0090-3493
    Sprache: Englisch
    Verlag: Ovid Technologies (Wolters Kluwer Health)
    Publikationsdatum: 2014
    ZDB Id: 2034247-0
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 6
    In: Pediatric Critical Care Medicine, Ovid Technologies (Wolters Kluwer Health), Vol. 19, No. 5 ( 2018-05), p. 421-432
    Kurzfassung: Pediatric in-hospital cardiac arrest cardiopulmonary resuscitation quality metrics have been reported in few children less than 8 years. Our objective was to characterize chest compression fraction, rate, depth, and compliance with 2015 American Heart Association guidelines across multiple pediatric hospitals. Design: Retrospective observational study of data from a multicenter resuscitation quality collaborative from October 2015 to April 2017. Setting: Twelve pediatric hospitals across United States, Canada, and Europe. Patients: In-hospital cardiac arrest patients (age 〈 18 yr) with quantitative cardiopulmonary resuscitation data recordings. Interventions: None. Measurements and Main Results: There were 112 events yielding 2,046 evaluable 60-second epochs of cardiopulmonary resuscitation (196,669 chest compression). Event cardiopulmonary resuscitation metric summaries (median [interquartile range]) by age: less than 1 year (38/112): chest compression fraction 0.88 (0.61–0.98), chest compression rate 119/min (110–129), and chest compression depth 2.3 cm (1.9–3.0 cm); for 1 to less than 8 years (42/112): chest compression fraction 0.94 (0.79–1.00), chest compression rate 117/min (110–124), and chest compression depth 3.8 cm (2.9–4.6 cm); for 8 to less than 18 years (32/112): chest compression fraction 0.94 (0.85–1.00), chest compression rate 117/min (110–123), chest compression depth 5.5 cm (4.0–6.5 cm). “Compliance” with guideline targets for 60-second chest compression “epochs” was predefined: chest compression fraction greater than 0.80, chest compression rate 100–120/min, and chest compression depth: greater than or equal to 3.4 cm in less than 1 year, greater than or equal to 4.4 cm in 1 to less than 8 years, and 4.5 to less than 6.6 cm in 8 to less than 18 years. Proportion of less than 1 year, 1 to less than 8 years, and 8 to less than 18 years events with greater than or equal to 60% of 60-second epochs meeting compliance (respectively): chest compression fraction was 53%, 81%, and 78%; chest compression rate was 32%, 50%, and 63%; chest compression depth was 13%, 19%, and 44%. For all events combined, total compliance (meeting all three guideline targets) was 10% (11/112). Conclusions: Across an international pediatric resuscitation collaborative, we characterized the landscape of pediatric in-hospital cardiac arrest chest compression quality metrics and found that they often do not meet 2015 American Heart Association guidelines. Guideline compliance for rate and depth in children less than 18 years is poor, with the greatest difficulty in achieving chest compression depth targets in younger children.
    Materialart: Online-Ressource
    ISSN: 1529-7535
    Sprache: Englisch
    Verlag: Ovid Technologies (Wolters Kluwer Health)
    Publikationsdatum: 2018
    ZDB Id: 2070997-3
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 7
    In: Circulation, Ovid Technologies (Wolters Kluwer Health), Vol. 142, No. Suppl_3 ( 2020-11-17)
    Kurzfassung: Introduction: Left heart decompression (LD) is performed in patients on veno-arterial extra-corporeal membrane oxygenation (ECMO) to decrease myocardial wall stress, enhance recovery and decrease complications. Data on outcomes following LD however, are unclear. We sought to evaluate outcomes of death(D) and hospital parameters with a systematic review and meta-analysis (SR-MA) in children without congenital heart disease (CHD) who underwent LD on ECMO. Methods: We included citations in non-CHD patients 〈 21 years age on ECMO, from a MESH search for ECMO, LD and D in CINAHL, CINAHL PLUS and MEDLINE, in English up to January 31, 2020. Case reports, systematic reviews, database duplicates and CHD outcomes were excluded. Cochrane ROBINS-I risk of bias (ROB) tool for non-randomized studies was used to assess ROB. Results: The search yielded 300 citations, reduced to 36 full text screening of which 7 met inclusion criteria. All were observational retrospective analysis (5 single centers, 2 registries). ROB was critical in 3 studies, and low in 2 (not assessed in 2 abstracts). Of 1,789 included pts, 1,575 were in registries. Median age on ECMO was 6 years and weight 18.7 (range 3-92) kgs. Main diagnoses consisted of myocarditis (n=636,36%) and dilated cardiomyopathy (n=919,52%). Overall, 659 pts died and 75 underwent heart transplantation. Time from ECMO to LD was 15.5 hours (0-113.7 hrs). Dynamic left atrial (LA) LD was performed in 239 pts(13%), static in 135(8%), LA drain in 150(8%) and atrial septal stent in 17(1%). Median LA pressure at the time of decompression was 21 mm Hg. Pts who underwent LD were found to have lower odds ratio for D compared to pts who did not (OR 0.73 [0.5-1.0],I 2 0%). There was inadequate data to assess outcomes of number of days on ECMO (1 study-LD 17+28 vs non-LD 6+4 days), mechanical ventilation (1 study- LD 32+49 vs non-LD 14+19 d), ICU stay (1 study-LD 52+55 vs non-LD 18+10 d) and total length of stay (1 study-LD 60+55 vs non-LD 27+33 d). Conclusions: Our systematic review and meta-analysis found that survival was better in non-CHD pts on ECMO who underwent LD compared to pts who did not. Further outcome analysis was limited by inadequate data. Larger registry level analysis is necessary to assess this further.
    Materialart: Online-Ressource
    ISSN: 0009-7322 , 1524-4539
    Sprache: Englisch
    Verlag: Ovid Technologies (Wolters Kluwer Health)
    Publikationsdatum: 2020
    ZDB Id: 1466401-X
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 8
    Online-Ressource
    Online-Ressource
    Ovid Technologies (Wolters Kluwer Health) ; 2019
    In:  Circulation Vol. 140, No. Suppl_2 ( 2019-11-19)
    In: Circulation, Ovid Technologies (Wolters Kluwer Health), Vol. 140, No. Suppl_2 ( 2019-11-19)
    Kurzfassung: Introduction: Diminished survival after cardiopulmonary resuscitation (CPR) has been shown in patients with congenital heart disease (CHD) and single ventricle (SV) anatomy compared to biventricular anatomy (BV). The role guideline-compliant CPR plays in SV outcomes is unknown. Hypothesis: During pediatric in-hospital cardiac arrest (IHCA), there will be a difference in CPR delivery and outcomes of patients with SV compared to BV anatomy. Methods: Prospective observational cohort from 12 pediRES-Q sites of IHCA in children ≤ 18 years with CPR quality metric data (chest compression (CC) rate, depth, and fraction (CCF)) (Zoll R-Series, Chelmsford, MA). We compared 60-sec CC epoch compliance with 2015 American Heart Association guideline targets defined as: CC rate 100-120/min; depth ≥4.0 cm in 〈 1 yo, ≥5 to ≤6 cm in 1- 〈 18 yo; and CCF ≥0.80. Total guideline compliance was defined as a CC event with ≥ 60% epochs meeting all targets. Metric summaries were reported as median [IQR] and compliance as frequency (%). Differences were assessed using Wilcoxon rank-sum and Fishers exact tests, respectively. Logistic regression assessed for associations with outcomes, including anatomy and proportion of guideline-compliant CPR. Results: From 10/2015 to 3/2019, we analyzed 82 events ( 〉 5 epochs) in patients with CHD. Thirty-seven percent had SV anatomy and more SV patients were post-operative (70% vs 2%). There were no differences in time to first epinephrine dose (1 vs 2 min), shockable rhythm (7% vs 6%), or need for ECMO (27% vs 23%). Total guideline compliance across all ages was not different (SV 10.0% vs BV 5.8%, P=0.67) and not associated with ROSC or survival to hospital discharge (SHD). There was a 75% lower adjusted odds of SHD in 1- 〈 8 yo vs 〈 1 yo. Conclusion: There were no meaningful differences in resuscitative practice or delivery of guideline-compliant CPR in those with SV versus BV anatomy. Guideline-compliant CPR was not associated with outcomes regardless of cardiac anatomy.
    Materialart: Online-Ressource
    ISSN: 0009-7322 , 1524-4539
    Sprache: Englisch
    Verlag: Ovid Technologies (Wolters Kluwer Health)
    Publikationsdatum: 2019
    ZDB Id: 1466401-X
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 9
    In: Circulation, Ovid Technologies (Wolters Kluwer Health), Vol. 144, No. Suppl_2 ( 2021-11-16)
    Kurzfassung: Introduction: Survival of adult patients with COVID-19 who had an in-hospital cardiac arrest (IHCA) are poor. Characteristics and outcomes for pediatric IHCA patients with COVID-19 are unknown. Hypothesis: We hypothesized that pediatric COVID-19 patients would have worse survival outcomes when compared to non-COVID patients. Methods: A multicenter, multinational cohort of pediatric IHCA in the pediRES-Q collaborative were reviewed (March 1, 2020 - April 1, 2021). We characterized patients with COVID-19 compared to patients without COVID-19 and investigated whether COVID-19 was associated with survival outcomes using multivariate logistic regression with mixed effects. Results: We identified 362 pediatric IHCAs of which 14 were COVID-19 positive. For non-COVID-19 vs COVID-19 patients respectively, median [Q1; Q3] age was 1.0 [0.3; 7.1] vs. 7.1 [1.5; 14.0] years and 42% vs. 43% were female. Immediate cause of arrest was hypotension: 8% vs. 43%, respiratory decompensation: 19% vs. 21%, and hypoxia 22% vs. 36% for non-COVID-19 vs. COVID-19 patients. For non-COVID-19 vs COVID-19 patients, total CPR duration was 10 [4; 33] min vs 19 [5; 33] min (for non-return of spontaneous circulation (ROSC) cases only: 35 [20; 55] min vs 34 [24; 34] min). For non-COVID-19 vs COVID-19 patients, ROSC was 79% vs. 57%, aOR: 0.48 (95% CI: 0.24-0.98), survival to hospital discharge was 45% vs. 29%, aOR: 0.63 (95% CI: 0.25-1.57) and survival with favorable neurological outcome was 39% vs. 21%, aOR: 0.51 (95% CI: 0.16-1.65). Conclusions: In a pediatric resuscitation quality improvement collaborative, pediatric IHCA patients with COVID-19 were older when compared to non-COVID-19 patients. Median CPR duration was 〉 30 minutes for COVID-19 non-survivors, COVID-19 patients had lower chance of ROSC when compared to non-COVID-19 patients but considerably better survival outcomes than those reported for adults.
    Materialart: Online-Ressource
    ISSN: 0009-7322 , 1524-4539
    Sprache: Englisch
    Verlag: Ovid Technologies (Wolters Kluwer Health)
    Publikationsdatum: 2021
    ZDB Id: 1466401-X
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 10
    Online-Ressource
    Online-Ressource
    Ovid Technologies (Wolters Kluwer Health) ; 2016
    In:  Critical Care Medicine Vol. 44, No. 12 ( 2016-12), p. 367-367
    In: Critical Care Medicine, Ovid Technologies (Wolters Kluwer Health), Vol. 44, No. 12 ( 2016-12), p. 367-367
    Materialart: Online-Ressource
    ISSN: 0090-3493
    Sprache: Englisch
    Verlag: Ovid Technologies (Wolters Kluwer Health)
    Publikationsdatum: 2016
    ZDB Id: 2034247-0
    Standort Signatur Einschränkungen Verfügbarkeit
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