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  • 1
    Online Resource
    Online Resource
    Elsevier BV ; 2014
    In:  Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Vol. 118, No. 2 ( 2014-08), p. 241-247
    In: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Elsevier BV, Vol. 118, No. 2 ( 2014-08), p. 241-247
    Type of Medium: Online Resource
    ISSN: 2212-4403
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2014
    detail.hit.zdb_id: 2001803-4
    detail.hit.zdb_id: 2650551-4
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  • 2
    Online Resource
    Online Resource
    Hindawi Limited ; 2013
    In:  Gastroenterology Research and Practice Vol. 2013 ( 2013), p. 1-5
    In: Gastroenterology Research and Practice, Hindawi Limited, Vol. 2013 ( 2013), p. 1-5
    Abstract: Purpose . The purpose of this study was to determine the incidence and predictors of hepatic encephalopathy (HE) after transjugular intrahepatic portosystemic shunt (TIPS) and endoscopic therapy (ET) in the elective treatment of recurrent variceal hemorrhage. Methods . Seventy patients were treated with elective TIPS and fifty-six patients with ET. Median observation time was 46.28 months in the TIPS group and 42.31 months in the ET group. Results . 30 patients (42.8%) developed clinically evident portosystemic encephalopathy in TIPS group and 20 patients (35.6%) in ET group. The difference between the groups was not statistically significant ( P = 0.542 ; χ 2 test). The incidence of new or worsening portosystemic encephalopathy was 24.3% in TIPS group and 10.7% in ET group. Multivariate analysis showed that ET treatment ( P = 0.031 ), age of 〉 65 years ( P = 0.022 ), pre-existing HE ( P = 0.045 ), and Child's class C ( P = 0.051 ) values were independent predictors for the occurrence of HE. Conclusions . Procedure-related HE is a complication in a minority of patients treated with TIPS or ET. Patients with increased age, preexisting HE, and higher Child-Pugh score should be carefully observed after TIPS procedure because the risk of post-TIPS HE in these patients is higher.
    Type of Medium: Online Resource
    ISSN: 1687-6121 , 1687-630X
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2013
    detail.hit.zdb_id: 2435460-0
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  • 3
    In: Radiology and Oncology, Walter de Gruyter GmbH, Vol. 49, No. 4 ( 2015-12-1), p. 341-346
    Abstract: Background. Endovascular embolization is a treatment of choice for the management of unruptured intracranial aneurysms, but sometimes is complicated with perianeurysmal oedema. The aim of our study was to establish incidence and outcomes of perianeurysmal oedema after endovascular coiling of unruptured intracranial aneurysms, and to reveal possible risk factors for development of this potentially serious complication. Methods. In total 119 adult patients with endovascular embolization of unruptured intracranial aneurysm (performed at Department for Interventional Neuroradiology, Clinical Center, Kragujevac, Serbia) were included in our study. The embolizations were made by electrolite-detachable platinum coils: pure platinum, hydrophilic and combination of platinum and hydrophilic coils. Primary outcome variable was perianeurysmal oedema visualized by magnetic resonance imaging (MRI) 7, 30 and 90 days after the embolization. Results. The perianurysmal oedema appeared in 47.6% of patients treated with hydrophilic coils, in 21.6% of patients treated with platinum coils, and in 53.8% of those treated with mixed type of the coils. The multivariate logistic regression showed that variables associated with occurrence of perianeurysmal oedema are volume of the aneurysm, hypertension, diabetes and smoking habit. Hypertension is the most important independent predictor of the perianeurysmal oedema, followed by smoking and diabetes. Conclusions. The results of our study suggest that older patients with larger unruptured intracranial aneurysms, who suffer from diabetes mellitus and hypertension, and have the smoking habit, are under much higher risk of having perianeurysmal oedema after endovascular coiling.
    Type of Medium: Online Resource
    ISSN: 1581-3207
    Language: English
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2015
    detail.hit.zdb_id: 2134813-3
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  • 4
    In: Radiology and Oncology, Walter de Gruyter GmbH, Vol. 54, No. 3 ( 2020-05-28), p. 253-262
    Abstract: Severe bleeding after blunt maxillofacial trauma is a rare but life-threatening event. Non-responders to conventional treatment options with surgically inaccessible bleeding points can be treated by transarterial embolization (TAE) of the external carotid artery (ECA) or its branches. Case series on such embolizations are small; considering the relatively high incidence of maxillofacial trauma, the ECA TAE procedure has been hypothesized either underused or underreported. In addition, the literature on the ECA TAE using novel non-adhesive liquid embolization agents is remarkably scarce. Patients and methods PubMed review was performed to identify the ECA TAE literature in the context of blunt maxillofacial trauma. If available, the location of the ECA injury, the location of embolization, the chosen embolization agent, and efficacy and safety of the TAE were noted for each case. Survival prognostic factors were also reviewed. Additionally, we present an illustrative TAE case using a precipitating hydrophobic injectable liquid (PHIL) to safely and effectively control a massive bleeding originating bilaterally in the ECA territories. Results and conclusions Based on a review of 205 cases, the efficacy of TAE was 79.4–100%, while the rate of major complications was about 2–4%. Successful TAE haemostasis, Glasgow Coma Scale score ≥ 8 at presentation, injury severity score ≤ 32, shock index ≤ 1.1 before TAE and ≤ 0.8 after TAE were significantly correlated with higher survival rate. PHIL allowed for fast yet punctilious application, thus saving invaluable time in life-threatening situations while simultaneously diminishing the possibility of inadvertent injection into the ECA-internal carotid artery (ICA) anastomoses.
    Type of Medium: Online Resource
    ISSN: 1581-3207
    Language: English
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2020
    detail.hit.zdb_id: 2134813-3
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  • 5
    Online Resource
    Online Resource
    Walter de Gruyter GmbH ; 2023
    In:  Radiology and Oncology Vol. 57, No. 2 ( 2023-06-01), p. 178-183
    In: Radiology and Oncology, Walter de Gruyter GmbH, Vol. 57, No. 2 ( 2023-06-01), p. 178-183
    Abstract: During the period of fetal development, myelination plays a key role and follows specific time and spatial sequences. The water content in the brain is inversely proportional to myelination – the more myelinated the brain, the lower the water content in it. The diffusion of water molecules can be quantitatively assessed using the apparent diffusion coefficient (ADC). We were interested in whether, by determining the ADC values, we could quantitatively evaluate the development of the fetal brain. Patients and methods The study included 42 fetuses with gestational age 25 to 35 weeks. We manually selected 13 regions on diffusion-weighted images. Statistically significant differences between ADC values were checked using one-way analysis of variance and Tukey's post hoc test. The relationship between the ADC values and the gestational age of the fetuses was then assessed using linear regression. Results The average gestational age of the fetuses was 29.8 ± 2.4 weeks. ADC values in the thalami, pons and cerebellum differed significantly among each other and from the ADC values in other brain regions. In the thalami, pons and cerebellum, linear regression showed a significant decrease in ADC values with increasing gestational age. Conclusions ADC values change with the increasing gestational age of the fetus and differ among different brain regions. In the pons, cerebellum and thalami, the ADC coefficient could be used as a biomarker of fetal brain maturation since ADC values decrease linearly with increasing gestational age.
    Type of Medium: Online Resource
    ISSN: 1581-3207
    Language: English
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2023
    detail.hit.zdb_id: 2134813-3
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  • 6
    Online Resource
    Online Resource
    Elsevier BV ; 2021
    In:  Radiology Case Reports Vol. 16, No. 9 ( 2021-09), p. 2651-2657
    In: Radiology Case Reports, Elsevier BV, Vol. 16, No. 9 ( 2021-09), p. 2651-2657
    Type of Medium: Online Resource
    ISSN: 1930-0433
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2021
    detail.hit.zdb_id: 2406300-9
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  • 7
    Online Resource
    Online Resource
    Walter de Gruyter GmbH ; 2016
    In:  Radiology and Oncology Vol. 50, No. 3 ( 2016-9-1), p. 263-268
    In: Radiology and Oncology, Walter de Gruyter GmbH, Vol. 50, No. 3 ( 2016-9-1), p. 263-268
    Abstract: The aim of the study was to investigate the sensitivity and specificity of non-contrast computed tomography (NCCT) in the diagnosis of cerebral venous sinus thrombosis (CVST). Methods. Screening our neurological department database, we identified 53 patients who were admitted to neurological emergency department with clinical signs of CVST. Two independent observers assessed the NCCT scans for the presence of CVST. CT venography and/or MR venography were used as a reference standard. Interobserver agreement between the two readers was assessed using Kappa statistic. Attenuation inside the cerebral venous sinuses was measured and compared between the patient and the control group. Results CVST was confirmed in 13 patients. Sensitivity and specificity of NCCT for overall presence of CVST were 100% and 83%, respectively, with Kappa value of 0.72 (a good agreement between observers). The attenuation values between CVST patients and control group were significantly different (73.4 ± 14.12 HU vs . 58.1 ± 7.58 HU; p = 0.000). The ROC analysis showed an area under the curve (AUC) of 0.916 (95% CI, 0.827 – 1.00) and an optimal cutoff value of 64 HU, leading to a sensitivity of 85% and specificity of 87%. Conclusions NCCT as a first-line investigation has a high value for diagnosis of CVST in the emergency setting. The additional measurement of the sinus attenuation may improve the diagnostic value of the examination.
    Type of Medium: Online Resource
    ISSN: 1581-3207
    Language: English
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2016
    detail.hit.zdb_id: 2134813-3
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  • 8
    Online Resource
    Online Resource
    Walter de Gruyter GmbH ; 2018
    In:  Radiology and Oncology Vol. 53, No. 1 ( 2018-12-20), p. 25-30
    In: Radiology and Oncology, Walter de Gruyter GmbH, Vol. 53, No. 1 ( 2018-12-20), p. 25-30
    Abstract: Intravenous thrombolysis (IVT) is the method of choice in reperfusion treatment of patients with signs and symptoms of acute ischemic stroke (AIS) lasting less than 4.5 hours. Hemorrhagic transformation (HT) of acute ischemic stroke is a serious complication of IVT and occurs in 4.5–68.0% of clinical cases. The aim of our study was to determine the infarct core CT perfusion parameter (CTPP) most predictive of HT. Patients and methods Seventy-five patients with AIS who had undergone CT perfusion (CTP) imaging and were treated with IVT were enrolled in this retrospective study. Patients with and without HT after IVT were defined as cases and controls, respectively. Controls were found by matching for time from AIS symptom onset to IVT ± 0.5 h. The following CTPPs were measured: cerebral blood flow (CBF), cerebral blood volume (CBV), mean transit time (MTT), relative CBF (rCBF) and relative CBV (rCBV). Receiver operating characteristic analysis curves of significant CTPPs determined cut-off values that best predict HT. Results There was a significant difference between cases and controls for CBF (p = 0.004), CBV (p = 0.009), rCBF (p 〈 0.001) and rCBV (p = 0.001). Receiver operating characteristic analysis revealed that rCBF 〈 4.5% of the contralateral mean (area under the curve = 0.736) allowed prediction of HT with a sensitivity of 71.0% and specificity of 52.5%. Conclusions CTP imaging has a considerable role in HT prediction, assisting in selection of patients that are likely to benefit from IVT. rCBF proved to have the highest HT predictive value.
    Type of Medium: Online Resource
    ISSN: 1581-3207
    Language: English
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2018
    detail.hit.zdb_id: 2134813-3
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  • 9
    Online Resource
    Online Resource
    Slovenian Medical Association ; 2020
    In:  Slovenian Medical Journal Vol. 89, No. 3-4 ( 2020-04-21), p. 203-222
    In: Slovenian Medical Journal, Slovenian Medical Association, Vol. 89, No. 3-4 ( 2020-04-21), p. 203-222
    Abstract: Nevrodegenerativne bolezni možganov, ki se klinično izrazijo kot demenca ali parkinsonizem, postajajo s staranjem prebivalstva vse pogostejše. Zgodnja in pravilna diagnoza je pomembna zaradi izključevanja ozdravljivih vzrokov, ustreznega simptomatskega zdravljenja, socialnih ukrepov in vključevanja bolnikov v klinične raziskave. Dokončno diagnozo večine nevrodegenerativnih bolezni možganov lahko postavimo le na podlagi patohistološkega vzorca možganovine. Za živa so nam v veliko pomoč funkcijske nuklearnomedicinske preiskave, s katerimi lahko prikažemo spremenjeno regionalno presnovo možganov, motnje na nivoju nevrotransmiterskih sistemov in patomorfološki substrat bolezni – kopičenje patoloških beljakovin. Glede na značilne spremembe regionalne presnove možganov, ki jih preučujemo s pozitronsko emisijsko tomografijo (PET) možganov z uporabo z radioaktivnim fluorom (18F) označene deoksiglukoze, lahko razlikujemo med alzheimerjevo boleznijo, demenco z lewyjevimi telesci, frontotemporalno demenco in redkejšimi vzroki kognitivnega upada ter med parkinsonovo boleznijo in drugimi nevrodegenerativnimi parkinsonizmi. Z ugotavljanjem integritete dopaminergičnega sistema (npr. scintigrafijo dopaminskega prenašalca; DaTSCAN) lahko razlikujemo med nevrodegenerativnimi parkinsonizmi in drugimi možnimi vzroki težav. Amiloidni PET možganov nam prikaže prisotnost in značilno razporeditev prekomernega kopičenja amiloida pri bolnikih z alzheimerjevo boleznijo že pred pojavom kliničnih znakov bolezni. V prispevku predstavljamo nuklearno medicinske preiskave, obravnavamo indikacije in značilne spremembe ter omejitve teh preiskav v diagnostiki nevrodegenerativnih bolezni možganov.
    Type of Medium: Online Resource
    ISSN: 1581-0224 , 1318-0347
    Language: Unknown
    Publisher: Slovenian Medical Association
    Publication Date: 2020
    detail.hit.zdb_id: 2502309-3
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  • 10
    In: BMC Psychiatry, Springer Science and Business Media LLC, Vol. 19, No. 1 ( 2019-12)
    Type of Medium: Online Resource
    ISSN: 1471-244X
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2019
    detail.hit.zdb_id: 2050438-X
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