In:
Collection of Czechoslovak Chemical Communications, Institute of Organic Chemistry & Biochemistry, Vol. 57, No. 7 ( 1992), p. 1516-1520
Abstract:
Derivatives of 1-(2-(2-dimethylaminoethyl)benzyliden)isoindolin-3-one underwent deamination on reaction with epoxides under mild conditions. Amide group of the substrate reacted slower with epoxide than the dimethylamino grouping whilst the alkanolamide was formed with a great excess of the epoxide only. Of epoxides used in this reaction 1,2-epoxy-3-phenoxypropane, 3-decyloxypropane and 3-chloro-1,2-epoxypropane, the first was found to react most rapidly.
Type of Medium:
Online Resource
ISSN:
0010-0765
,
1212-6950
DOI:
10.1135/cccc19921516
Language:
English
Publisher:
Institute of Organic Chemistry & Biochemistry
Publication Date:
1992
Permalink