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  • 1
    In: Oxidative Medicine and Cellular Longevity, Hindawi Limited, Vol. 2022 ( 2022-11-14), p. 1-14
    Abstract: Background. Metabolic alterations, particularly disorders of lipoprotein metabolism in COVID-19, may affect the course and outcome of the disease. This study aims at evaluating the lipoprotein profile and redox status in SARS-CoV-2 infected patients with different pneumonia severity and their association with lethal outcomes. Methods. The prospective cohort study was performed on 98 COVID-19 patients with mild, moderate, and severe pneumonia. Lipid and inflammatory parameters, lipoprotein subclasses, and redox status biomarkers were determined at the study entry and after one week. Results. Compared to patients with mild and moderate pneumonia, severely ill patients had higher oxidised low-density lipoprotein (oxLDL) and malondialdehyde levels and lower high-density lipoprotein cholesterol (HDL-C) concentrations and paraoxonase 1 activity. Reduction in the proportion of large HDL 2a subclasses with a concomitant increase in the proportion of smallest HDL 3c and small dense LDL (sdLDL) particles was observed in patients with severe disease during the time. However, these changes were reversed in the mild and moderate groups. The results showed a positive association between changes in oxLDL and total antioxidative status. However, prooxidants and antioxidants in plasma were lower in patients with lethal outcomes. Conclusions. Increased levels of oxLDL and sdLDL particles may contribute to the severity of COVID-19. The role of oxidative stress should be clarified in further studies, mainly its association with lethal outcomes.
    Type of Medium: Online Resource
    ISSN: 1942-0994 , 1942-0900
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2022
    detail.hit.zdb_id: 2455981-7
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  • 2
    In: Horticulturae, MDPI AG, Vol. 7, No. 11 ( 2021-10-20), p. 420-
    Abstract: The aim of this study was to evaluate the content and profile of the phenolic compounds (PCs) and antioxidant properties of field-grown leaves, in vitro leaves and in vitro callus cultures of the blackberry ‘Čačanska Bestrna’ and blueberry ‘Toro’. In vitro shoots of the selected genotypes were grown either on original Murashige and Skoog (MS) medium containing 1 mg/L BA, 0.1 mg/L IBA and 0.1 mg/L GA3 (‘Čačanska Bestrna’) or on MS medium with macroelements reduced to ½, 2 mg/L zeatin and 0.2 mg/L IAA (‘Toro’). Callus cultures were induced from in vitro leaves and established on MS medium with 2 mg/L BA and 2 mg/L 2,4-D (‘Čačanska Bestrna’) or MS medium with half strength macroelements, 2 mg/L BA, 2 mg/L 2,4-D and 1 mg/L NAA (‘Toro’). Total phenolic (TPC) and flavonoid content (TFC) were the highest in blueberry leaves, whereas low TPC and TFC values were obtained in callus cultures of both cultivars. A higher content of PCs in blueberry leaves compared to blackberry leaves was determined by the UHPLC-DAD MS/MS technique. Quercetin derivatives and phenolic acids were the dominant PCs in the leaves of both berries, whereas gallocatechin was present in a significant amount in blueberry leaves. Callus cultures of both berries had a specific PC profile, with none detected in the leaves except quercetin-3-O-glucoside and quercetin-3-O-rutinoside. Blackberry leaves showed the best antioxidant properties as estimated by ferric reducing power (FRP), ABTS•+ and DPPH• scavenging activity assays. Callus cultures of both berries exhibited three to five times lower ABTS•+ and ten to seventeen times lower DPPH• scavenging activity compared to corresponding leaves. The analyzed leaves and callus cultures can be a good source of PCs with good antioxidant properties and specific phenolics, respectively, for applications in the food and pharmaceutical industries.
    Type of Medium: Online Resource
    ISSN: 2311-7524
    Language: English
    Publisher: MDPI AG
    Publication Date: 2021
    detail.hit.zdb_id: 2813983-5
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  • 3
    Online Resource
    Online Resource
    CAIRN ; 2013
    In:  Langue française Vol. n°179, No. 3 ( 2013-12-1), p. 3-12
    In: Langue française, CAIRN, Vol. n°179, No. 3 ( 2013-12-1), p. 3-12
    Type of Medium: Online Resource
    ISSN: 0023-8368
    RVK:
    RVK:
    Language: French
    Publisher: CAIRN
    Publication Date: 2013
    detail.hit.zdb_id: 2098941-6
    detail.hit.zdb_id: 214779-8
    SSG: 7,30
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  • 4
    Online Resource
    Online Resource
    Journal of Infection in Developing Countries ; 2021
    In:  The Journal of Infection in Developing Countries Vol. 15, No. 10 ( 2021-10-31), p. 1515-1522
    In: The Journal of Infection in Developing Countries, Journal of Infection in Developing Countries, Vol. 15, No. 10 ( 2021-10-31), p. 1515-1522
    Abstract: Introduction: Ocular toxoplasmosis is the most common cause of infectious posterior uveitis worldwide. It can be prenatal or postnatal in origin. Despite estimations that postnatal ocular toxoplasmosis is more prevalent, only several cases of proven postnatal ocular toxoplasmosis have been reported in non-epidemic settings. Here, the clinical evolution of ocular toxoplasmosis of conclusively proven postnatal origin in immunocompetent patients is reported. Methodology: Postnatal ocular toxoplasmosis was diagnosed based on clinical diagnosis supported by the longitudinal detection of Toxoplasma gondii-specific IgG, IgM and IgA antibodies in the serum as well as by direct detection of the parasite (bioassay) and/or its DNA (real-time PCR) in aqueous humor. Results: Three cases involved adults in whom ocular toxoplasmosis developed during primary T. gondii infection, as part of the clinical presentation in two and as the sole manifestation in one patient. The fourth patient was a case of inactive ocular toxoplasmosis in a 14-year-old boy, where postnatal infection was confirmed by exclusion of maternal infection. The causative parasite strain was genotyped in only one case and it belonged to genotype II, the dominant type in Europe. One patient acquired the infection in Africa, suggesting an atypical strain. Conclusions: The distinction between prenatal and postnatal ocular toxoplasmosis is only possible in particular clinical situations, and requires extensive laboratory investigation. Genotyping of the parasite strain involved may be important, particularly if atypical strains are suspected, requiring tailored treatment approaches.
    Type of Medium: Online Resource
    ISSN: 1972-2680
    Language: Unknown
    Publisher: Journal of Infection in Developing Countries
    Publication Date: 2021
    detail.hit.zdb_id: 2394024-4
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  • 5
    Online Resource
    Online Resource
    Centre for Evaluation in Education and Science (CEON/CEES) ; 2021
    In:  Zbornik radova Filozofskog fakulteta u Pristini Vol. 51, No. 1 ( 2021), p. 45-62
    In: Zbornik radova Filozofskog fakulteta u Pristini, Centre for Evaluation in Education and Science (CEON/CEES), Vol. 51, No. 1 ( 2021), p. 45-62
    Abstract: The main goal of this research was to construct a scale to assess health beliefs about COVID-19, in the light of the Health Beliefs Model (Rosenstock, 1966). The study included 420 subjects, mean age M = 31.65 years (SD = 12.72). Two-thirds (76%) of the respondents were female. The respondents filled in a set of questionnaires via the Internet. At the very beginning, the purpose and goal of the research were explained and the consent for participation in the research was obtained. The survey was anonymous, while the data were collected from April to September, 2020. The COVID-19 Health Belief Scale showed satisfactory psychometric characteristics. Factor analysis has shown that four main components can be distinguished, which correspond to the types of beliefs included in the Health Beliefs Model (Rosenstock, 1966). Thus, four subscales were obtained: Perceived susceptibility to COVID-19 (four items), Perceived severity of COVID-19 (four items), Perceived benefit of preventive behaviour (four items), and Observed barriers to preventive behaviour (three items). This scale structure corresponds to other similar scales (HBMS, Champion, 1984; AHBS, Zagumny & Brady, 1998), based on the Health Beliefs Model (Rosenstock, 1966). The obtained average values of scores on the observed susceptibility to COVID-19 show that our respondents do not consider themselves either extremely susceptible or protected from contracting this disease. On the other hand, it is obvious that our respondents do not consider COVID-19 to be a serious enough disease, despite daily warnings that the disease is unpredictable and its consequences are serious, long - term, and even more frequent than of other viral diseases. The observed barriers to preventive behaviour are relatively low, as are the scores on the subscale. The observed benefits of preventive behaviour range from the highest possible scores. When we summarize these results, we can conclude that our respondents apply preventive measures, because they are convinced that they are useful in preventing infection, and that obstacles to their implementation have not been observed to a significant extent. However, it remains unclear why this disease is not considered serious enough. One possibility is that the information placed in the media was initially ambiguous, ranging from describing COVID-19 as a common respiratory infection to a serious illness with severe consequences. We can look for another explanation within our sample. Namely, the age of our average respondent was 31, and as many as two thirds of the respondents were women. Initial information about COVID-19, placed through the media, was that this disease seriously affects older people and, for the most part, males. Women perceived significantly more benefits from preventive behaviour, and men significantly more barriers. Respondents' burden of a chronic disease proved to be significant for two subscales: Perceived susceptibility to COVID-19 and Observed barriers to the implementation of preventive behaviour. People suffering from a chronic disease believe that they are more susceptible to the COVID-19 infection, i.e. that they are more susceptible to this disease compared to those who do not have chronic diseases. However, people burdened with a chronic disease notice several obstacles to the implementation of preventive measures at the same time. When it comes to the higher observed susceptibility to COVID-19 in married people compared to those who are not, we can assume several factors that lead to this: reduced possibility of isolation, double possibility of infection, greater social interaction due to different needs, and the like. This research has its limitations. Most importantly, we could not thoroughly examine the validity of the instrument, due to the lack of similar scales. Another important limitation is that the sample was mostly made up of women. The third important limitation concerns the average age of the respondents; this study covered only a small number of the elderly, who are most at risk during this pandemic. Nevertheless, we believe that the timeliness and novelty of the constructed scale are sufficient to indicate the need to use it, at least as a first step in the development of some future scales with a similar purpose. Recommendations for future research are such that they should respond to the stated limitations of this research; to be directed towards a thorough validation, towards different types of samples, but also towards studying both the predictors of these health beliefs and the value of these beliefs for predicting some forms of health behaviour, quality of life, adherence to medical instructions, etc.
    Type of Medium: Online Resource
    ISSN: 0354-3293 , 2217-8082
    Uniform Title: Zdravstvena uverenja prema kovidu 19 - instrument za procenu i izraženost uverenja
    Language: English
    Publisher: Centre for Evaluation in Education and Science (CEON/CEES)
    Publication Date: 2021
    detail.hit.zdb_id: 2927010-8
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  • 6
    Online Resource
    Online Resource
    Centre for Evaluation in Education and Science (CEON/CEES) ; 2022
    In:  Zbornik radova Filozofskog fakulteta u Pristini Vol. 52, No. 3 ( 2022), p. 301-316
    In: Zbornik radova Filozofskog fakulteta u Pristini, Centre for Evaluation in Education and Science (CEON/CEES), Vol. 52, No. 3 ( 2022), p. 301-316
    Abstract: The end of 2019 and the beginning of 2020 were marked by the appearance of the virus SARS-CoV-2, which led to a health crisis around the world. Health preventive behavior was highlighted as, at that time, the only form of prevention of the spread of the disease. Factors that will lead people to adhere to the recommended forms of behavior have become the subject of research in various scientific disciplines. The Model of Health Belief is one of the dominant frameworks for studying health behaviors, and thus behaviors related to COVID-19. Health anxiety and beliefs about illness and preventive behavior are the starting point for considering the level at which individuals adhere to the recommended measures. The main goal of this research was to examine a model in which health anxiety and health beliefs are predictors of preventive health behavior in relation to COVID-19. The sample consisted of 420 respondents, 66.3% of whom were women. They completed an online questionnaire comprising the following instruments: Short Health Anxiety Inventory, COVID-19 Health Belief Scale, and COVID-19 Health Behavior Scale with two subscales-Protection in Social Contacts and Hygiene. After controlling for effects of gender and presence of chronic disease, perceived benefit of preventive behavior and the observed barrier can predict protection in social contacts. Hygiene can be predicted by the perceived benefit of preventive behavior and the perceived barrier. Health anxiety has not been shown to be a significant predictor of health behavior. The paper discusses the theoretical and practical implications of the obtained results. The obtained results partially support the Model of Health Beliefs. In order to increase the degree to which individuals adhere to health behaviors, the benefits of preventive behaviors should be emphasized while the barriers should be reduced.
    Type of Medium: Online Resource
    ISSN: 0354-3293 , 2217-8082
    Uniform Title: Zdravstvena uverenja i zdravstvena anksioznost kao prediktori zdravstvenog ponašanja tokom pandemije kovida 19 - podaci iz Srbije
    Language: English
    Publisher: Centre for Evaluation in Education and Science (CEON/CEES)
    Publication Date: 2022
    detail.hit.zdb_id: 2927010-8
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  • 7
    In: BMC Public Health, Springer Science and Business Media LLC, Vol. 19, No. 1 ( 2019-12)
    Type of Medium: Online Resource
    ISSN: 1471-2458
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2019
    detail.hit.zdb_id: 2041338-5
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  • 8
    In: Plants, MDPI AG, Vol. 10, No. 12 ( 2021-12-20), p. 2814-
    Abstract: An annual plant, Himalayan balsam (Impatiens glandulifera Royle) is globally widespread and one of Europe’s top invaders. We focused on two questions: does this species indeed not invade the southern areas and does the environment affect some of its key invisibility traits. In an isolated model mountainous valley, we jointly analyzed the soil (21 parameters), the life history traits of the invader (height, stem diameter, aboveground dw), and the resident vegetation (species composition and abundances, Ellenberg indicator values), and supplemented it with local knowledge (semi-structured interviews). Uncontrolled discharge of fecal wastewaters directly into the local dense hydrological network fostered mass infestation of an atypical habitat. The phenotypic plasticity of the measured invasion-related traits was very high in the surveyed early invasion (30–50% invader cover) stages. Different microhabitat conditions consistently correlated with its growth performance. The largest individuals were restricted to the deforested riparian habitats, with extreme soil nutrient enrichment (primarily by P and K) and low-competitive, species-poor resident vegetation. We showed that ecological context can modify invasion-related traits and what could affect a further invasion process. Finally, this species is likely underreported in the wider region; public attitude and loss of traditional ecological knowledge are further management risks.
    Type of Medium: Online Resource
    ISSN: 2223-7747
    Language: English
    Publisher: MDPI AG
    Publication Date: 2021
    detail.hit.zdb_id: 2704341-1
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  • 9
    In: Hrana i ishrana, Centre for Evaluation in Education and Science (CEON/CEES), Vol. 59, No. 2 ( 2018), p. 26-32
    Type of Medium: Online Resource
    ISSN: 0018-6872 , 2560-452X
    Uniform Title: Predtretman zeolitom ostvaruje delimično radioprotektivni efekat na mozak smanjujuc'i gvožđe i oksidativni/nitrozativni stres kod pacova
    Language: English
    Publisher: Centre for Evaluation in Education and Science (CEON/CEES)
    Publication Date: 2018
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  • 10
    Online Resource
    Online Resource
    Centre for Evaluation in Education and Science (CEON/CEES) ; 2009
    In:  Zdravstvena zastita Vol. 38, No. 6 ( 2009), p. 17-26
    In: Zdravstvena zastita, Centre for Evaluation in Education and Science (CEON/CEES), Vol. 38, No. 6 ( 2009), p. 17-26
    Type of Medium: Online Resource
    ISSN: 0350-3208
    Uniform Title: Zoonoze na području Beograda - neprepoznate opasnosti po zdravlje ljudi
    Language: English
    Publisher: Centre for Evaluation in Education and Science (CEON/CEES)
    Publication Date: 2009
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