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  • 1
    Online Resource
    Online Resource
    American Society of Neuroradiology (ASNR) ; 2012
    In:  American Journal of Neuroradiology Vol. 33, No. 8 ( 2012-09), p. 1449-1454
    In: American Journal of Neuroradiology, American Society of Neuroradiology (ASNR), Vol. 33, No. 8 ( 2012-09), p. 1449-1454
    Type of Medium: Online Resource
    ISSN: 0195-6108 , 1936-959X
    RVK:
    RVK:
    Language: English
    Publisher: American Society of Neuroradiology (ASNR)
    Publication Date: 2012
    detail.hit.zdb_id: 2025541-X
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  • 2
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 2016
    In:  Medical Care Vol. 54, No. 5 ( 2016-05), p. 430-434
    In: Medical Care, Ovid Technologies (Wolters Kluwer Health), Vol. 54, No. 5 ( 2016-05), p. 430-434
    Abstract: Guidelines recommend that patients with stroke or transient ischemic attack (TIA) undergo neuroimaging and cardiac investigations to determine etiology and guide treatment. It is not known how the use of these investigations has changed over time and whether there have been associated changes in management. Objectives: To evaluate temporal trends in the use of brain and vascular imaging, echocardiography, and antithrombotic and surgical therapy after stroke or TIA. Research Design: We analyzed 42,738 patients with stroke or TIA presenting to any of the 11 regional stroke centers in Ontario, Canada between 2003 and 2012 using the Ontario Stroke Registry database. The study period was divided into 1-year intervals and we used the Cochran-Armitage test to determine trends over time. Results: Between 2003/2004 and 2011/2012, the proportion of patients undergoing brain imaging increased from 96% to 99%, as did the proportion receiving ≥3 brain scans (21%–39%), magnetic resonance imaging (13%–50%), vascular imaging (62%–88%), or echocardiography (52%–70%) ( P 〈 0.0001 for all comparisons). There was an increase in the proportion receiving any antithrombotic therapy (83%–91%, P 〈 0.0001) but no change in use of anticoagulation (25% overall and 68% in subgroup with atrial fibrillation) or carotid revascularization (1.4%–1.5%, P =0.49). Conclusions: The use of investigations after stroke has increased over time without concomitant changes in medical or surgical management. Although initial neurovascular imaging is in accordance with practice guidelines, the use of multiple imaging procedures and routine echocardiography are of uncertain clinical effectiveness.
    Type of Medium: Online Resource
    ISSN: 0025-7079
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2016
    detail.hit.zdb_id: 2045939-7
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  • 3
    In: Neurology, Ovid Technologies (Wolters Kluwer Health), Vol. 88, No. 1 ( 2017-01-03), p. 57-64
    Abstract: To determine the risk of fractures after stroke. Methods: Using the Ontario Stroke Registry, we identified a population-based sample of consecutive patients seen in the emergency department or hospitalized with stroke (n = 23,751) or TIA (n = 11,240) at any of 11 stroke centers in Ontario, Canada, and discharged alive between July 1, 2003, and March 31, 2012. We compared the risk of low-trauma fractures in patients with stroke vs those with TIA using propensity score methods to adjust for differences in baseline factors. Secondary analyses compared fracture risk poststroke with that in age-/sex-matched controls without stroke or TIA (n = 23,751) identified from the Ontario Registered Persons Database. Results: The 2-year rate of fracture was 5.7% in those with stroke compared to 4.8% in those with TIA (adjusted cause-specific hazard ratio [aHR] for those with stroke vs TIA 1.32; 95% confidence interval [CI] 1.19–1.46) and 4.1% in age-/sex-matched controls (aHR for those with stroke vs controls 1.47; 95% CI 1.35–1.60). In the cohort with stroke, factors associated with fractures were older age, female sex, moderate stroke severity, prior fractures or falls, and preexisting osteoporosis, rheumatoid arthritis, hyperparathyroidism, and atrial fibrillation. Conclusions: Stroke is associated with an increased risk of low-trauma fractures. Individuals with stroke and additional risk factors for fractures may benefit from targeted screening for low bone mineral density and initiation of treatment for fracture prevention.
    Type of Medium: Online Resource
    ISSN: 0028-3878 , 1526-632X
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    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2017
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  • 4
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 2014
    In:  Stroke Vol. 45, No. suppl_1 ( 2014-02)
    In: Stroke, Ovid Technologies (Wolters Kluwer Health), Vol. 45, No. suppl_1 ( 2014-02)
    Abstract: Background: Current guidelines recommend that patients with suspected stroke undergo neuroimaging to confirm the diagnosis and that those with ischemic stroke or TIA receive carotid imaging and cardiac investigations to determine stroke etiology. It is not known how rates of investigations have changed over time, and if those trends have led to changes in medical or surgical management. We used a clinical stroke registry to evaluate temporal trends in stroke investigations in Ontario, Canada. Methods: We used the Ontario Stroke Registry to identify patients who presented with stroke and TIA to 11 stroke centers between 2003 and 2012. The primary outcome was the proportion of patients who received CT, MRI, CTA, MRA, carotid doppler, and echocardiography in each year. Secondary outcomes were (1) the total number of neuroimaging procedures per patient; (2) the proportion of patients with ischemic stroke/TIA prescribed antithrombotics at discharge; and (3) the proportion who had carotid revascularization. The characteristics of study participants, rates of investigations and interventions, and test for trends over one year intervals were completed using a Cochran-Armitage trend test. Results: The study sample included 42,738 patients. From 2003 to 2012, the proportion receiving any type of neuroimaging increased from 96% to 99%, those receiving an MRI increased from 10% to 49%, those receiving carotid imaging increased from 62% to 88% and those receiving echocardiography increased from 52% to 70% (P 〈 0.0001 for all comparisons). The total number of neuroimaging procedures per patient also increased, from a median of 1 in 2003 to 3 in 2011 (P 〈 0.0001), and with almost 40% undergoing three or more neuroimaging procedures in 2011. In those with ischemic stroke or TIA, rates of antithrombotic therapy increased from 83% to 91%, as did the rate of carotid endarterectomy, from 0.7% to 0.8%. (P 〈 0.009). Conclusions: Rates of neuroimaging, carotid imaging and cardiac investigations after stroke have markedly increased over time. It is uncertain whether the increased rates of MRI and neuroimaging per patient are associated with improved outcomes. Further research is needed to evaluate the cost-effectiveness of current patterns of investigations following stroke.
    Type of Medium: Online Resource
    ISSN: 0039-2499 , 1524-4628
    RVK:
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2014
    detail.hit.zdb_id: 1467823-8
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