In:
Scientific Reports, Springer Science and Business Media LLC, Vol. 12, No. 1 ( 2022-08-23)
Abstract:
We aimed to evaluate the radiographic and clinical outcomes after gamma knife radiosurgery (GKRS) for trigeminal schwannomas (TSs). A total of 87 patients who underwent GKRS for TSs between 1990 and 2020 were enrolled. The mean tumor volume was 4.3 cm 3 . The median prescribed dose for the margins of the tumor was 13 Gy. The median follow-up duration was 64.3 months (range 12.0–311.5 months). The overall local tumor control rate was 90%, and the symptom response rate was 93%. The response rate for each symptom was 88% for facial pain, 97% for facial sensory change, and 86% for cranial nerve deficits. Nineteen (22%) patients showed transient swelling, which had regressed at the time of the last follow-up. Cystic tumors were associated with transient swelling ( p = 0.04). A tumor volume of 〈 2.7 cm 3 was associated with local tumor control in univariable analysis. Transient swelling was associated with symptom control failure in both univariable and multivariable analyses ( p = 0.04, odds ratio 14.538). GKRS is an effective treatment for TSs, both for local control and symptom control.
Type of Medium:
Online Resource
ISSN:
2045-2322
DOI:
10.1038/s41598-022-18689-5
Language:
English
Publisher:
Springer Science and Business Media LLC
Publication Date:
2022
detail.hit.zdb_id:
2615211-3
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