In:
Science, American Association for the Advancement of Science (AAAS), Vol. 334, No. 6052 ( 2011-10-07), p. 105-108
Abstract:
Diet strongly affects human health, partly by modulating gut microbiome composition. We used diet inventories and 16 S rDNA sequencing to characterize fecal samples from 98 individuals. Fecal communities clustered into enterotypes distinguished primarily by levels of Bacteroides and Prevotella . Enterotypes were strongly associated with long-term diets, particularly protein and animal fat ( Bacteroides ) versus carbohydrates ( Prevotella ). A controlled-feeding study of 10 subjects showed that microbiome composition changed detectably within 24 hours of initiating a high-fat/low-fiber or low-fat/high-fiber diet, but that enterotype identity remained stable during the 10-day study. Thus, alternative enterotype states are associated with long-term diet.
Type of Medium:
Online Resource
ISSN:
0036-8075
,
1095-9203
DOI:
10.1126/science.1208344
Language:
English
Publisher:
American Association for the Advancement of Science (AAAS)
Publication Date:
2011
detail.hit.zdb_id:
128410-1
detail.hit.zdb_id:
2066996-3
detail.hit.zdb_id:
2060783-0
SSG:
11
Permalink