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  • 1
    In: EFORT Open Reviews, Bioscientifica, Vol. 7, No. 12 ( 2022-12-01), p. 792-799
    Abstract: Patients undergoing major orthopedic surgeries, such as total hip replacement (THR), total knee replacement (TKR), and trauma surgery, are at an elevated risk of venous thromboembolism (VTE), causing significant morbidity and mortality. Previous studies have investigated aspirin as a thromboprophylactic agent for arthroplasty, besides trauma surgery. Therefore, we sought to analyze the efficacy of aspirin compared to that of other anticoagulants for VTE prophylaxis in patients undergoing major orthopedic surgeries. Methods This study was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The study protocol was registered with the PROSPERO register. Randomized controlled trials that investigated the use of aspirin for thromboprophylaxis in major orthopedic lower limb surgeries were included and analyzed. Quality analysis of the literature and level of evidence were assessed. The primary clinical outcome was VTE. Secondary clinical outcomes included mortality, bleeding events, and wound complications. Results Eight high-quality studies with level 2 evidence (published within 2006–2021) were included, comprising 6220 patients. The incidence of VTE with aspirin was not found to be more significant than other anticoagulants (risk ratio (RR) = 1.18, 95% CI: 0.89–1.58, P  = 0.25). Regarding secondary outcomes, there were no significant differences between aspirin and other anticoagulants (mortality (RR = 1.40, 95% CI: 0.27–7.23, P = 0.69), bleeding events (RR = 0.89, 95% CI: 0.57–1.39, P = 0.61), or wound complications (RR = 0.64, 95% CI: 0.30–1.35, P  = 0.24)). Conclusion The current meta-analysis did not show any difference between aspirin and other anticoagulants as thromboprophylactic agents in preventing VTE in patients who underwent major orthopedic surgeries.
    Type of Medium: Online Resource
    ISSN: 2058-5241
    Language: Unknown
    Publisher: Bioscientifica
    Publication Date: 2022
    detail.hit.zdb_id: 2844421-8
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  • 2
    Online Resource
    Online Resource
    Elsevier BV ; 2023
    In:  International Journal of Surgery Case Reports Vol. 111 ( 2023-10), p. 108843-
    In: International Journal of Surgery Case Reports, Elsevier BV, Vol. 111 ( 2023-10), p. 108843-
    Type of Medium: Online Resource
    ISSN: 2210-2612
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2023
    detail.hit.zdb_id: 2558001-2
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  • 3
    Online Resource
    Online Resource
    Badan Analisis dan Pengembangan Ilmiah Nasional - Ikatan Senat Mahasiswa Kedokteran Indonesia ; 2020
    In:  JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol. 7, No. 2 ( 2020-03-18), p. 115-121
    In: JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia, Badan Analisis dan Pengembangan Ilmiah Nasional - Ikatan Senat Mahasiswa Kedokteran Indonesia, Vol. 7, No. 2 ( 2020-03-18), p. 115-121
    Abstract: Pendahuluan: Penyakit kardiovaskular adalah penyakit dengan tingkat kematian tertinggidi dunia. Angka kematian di Indonesia pada tahun 2016 sebesar 37%. Salah satupenyebab penyakit kardiovaskular adalah penyakit autoimun. Artritis Reumatoid (RA)adalah penyakit autoimun yang sering menimbulkan komplikasi penyakit kardiovaskuler.Tatalaksana yang tepat pada penyakit RA akan mencegah komplikasi kardiovaskuler.Pembahasan: Artritis reumatoid adalah penyakit inflamasi kronis yang berdampak padapersendian. Inflamasi kronis ini juga menyebabkan efek pada pembuluh darah denganmenyebabkan terbentuknya aterosklerosis. Pada pasien RA, aterosclerosis disebabkanoleh sitokin proinflamasi, seperti IL-6 dan TNF-α, yang mengaktivasi reaksi imun danmenyebabkan terbentuknya plak hingga dapat menyebabkan ruptur. Selain prosesinflamasi, obat antiinflamasi non steroid yang seringkali digunakan untuk mengobati RA,juga dapat meningkatkan resiko penyakit kardiovaskular sebanyak 2-3 kali. OAINSmemiliki hubungan dengan apoptosis sel dan memiliki efek kardiotoksik akibat peningkatanROS dan kolesterol yang dapat menyebabkan penyakit kardiovaskular. Beberapapenelitian menemukan anti-IL-1β antibodi monoklonal yang disebut Canakinumab. IL-1βadalah mediator inflamasi yang poten. Canakinumab bekerja dengan cara menetralisirsinyal dari IL-1β dan menurunkan inflamasi pada pasien dengan penyakit autoimunsehingga mengurangi kemungkinan pasien terkena penyakit kardiovaskular. Penelitianyang dilakukan untuk mengetahui dosis poten Canakinumab, menemukan bahwa 150 mgCanakinumab selama dua minggu adalah dosis paling poten. Kesimpulan: Berdasarkanpenelitian yang telah dilakukan, dapat disimpulkan bahwa antibodi monoklonal dapatdigunakan sebagai terapi pilihan pada penderita RA untuk mencegah terjadinya penyakitkardiovaskular terkait dengan RA.
    Type of Medium: Online Resource
    ISSN: 2721-1924 , 2302-6391
    Language: Unknown
    Publisher: Badan Analisis dan Pengembangan Ilmiah Nasional - Ikatan Senat Mahasiswa Kedokteran Indonesia
    Publication Date: 2020
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  • 4
    Online Resource
    Online Resource
    Ikatan Dokter Indonesia ; 2021
    In:  Journal Of The Indonesian Medical Association Vol. 71, No. 5 ( 2021-11-27), p. 206-208
    In: Journal Of The Indonesian Medical Association, Ikatan Dokter Indonesia, Vol. 71, No. 5 ( 2021-11-27), p. 206-208
    Abstract: Chronic venous insufficiency (CVI) is a disease of the vein due to valve dysfunction, venous obstruction, or both. This results in increased vein pressure and related to disruption in the vein system.
    Type of Medium: Online Resource
    ISSN: 2654-3796 , 2089-1067
    URL: Issue
    Language: Unknown
    Publisher: Ikatan Dokter Indonesia
    Publication Date: 2021
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  • 5
    In: Annals of Medicine & Surgery, Ovid Technologies (Wolters Kluwer Health), Vol. 85, No. 6 ( 2023-05-17), p. 3179-3186
    Abstract: Reconstruction after en-bloc resection can be challenging in cases of Campanacci grade 3 giant cell tumour of the bone (GCTB) of the distal radius. Here, the authors examined the outcomes of patients with Campanacci grade 3 GCTBs of the distal radius who underwent wrist arthrodesis and reconstruction with ulnar translocation. Material and methods: This case series was a retrospective single-centre study. Clinical assessments regarding the functional status and complications were follow-up. The functional results were evaluated using the Musculoskeletal Tumor Society (MSTS) and Disability of Arm, Shoulder, and Hand (DASH) Score. Paired t -tests were used to compare the MSTS and DASH scores separately before and after the operation. Statistical differences were considered significant at P less than 0.05. Results: Seven patients were included in this study. The mean follow-up period was 14.43±8.08 months. The average length of tumour resection was 9.78±2.88 cm. The average range of motion of the involved forearm was 82.66° of supination and 81.54° of pronation. The average MSTS score was 11.71±2.21 before and 25.14±2.41 after the operation ( P 〈 0.05). The average DASH score on admission was 40.14±14.66, which decreased to 9.02±4.23 after the operation ( P 〈 0.05). Of the seven cases, one case had a recurrence, and one patient had radioulnar synostosis. Conclusion: Wrist arthrodesis combined with ulnar translocation can be considered a simple and effective reconstruction method with preservation of function after en-bloc resection of Campanacci grade 3 GCTB of the distal radius. It provides good functional outcomes with low complication rates.
    Type of Medium: Online Resource
    ISSN: 2049-0801
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2023
    detail.hit.zdb_id: 2745440-X
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  • 6
    Online Resource
    Online Resource
    SAGE Publications ; 2023
    In:  Orthopaedic Journal of Sports Medicine Vol. 11, No. 2_suppl ( 2023-01-01), p. 2325967121S0090-
    In: Orthopaedic Journal of Sports Medicine, SAGE Publications, Vol. 11, No. 2_suppl ( 2023-01-01), p. 2325967121S0090-
    Abstract: Lateral epicondylitis (LE), also commonly known as tennis elbow, is one of the most common causes of lateral epicondyle pain. Most LE cases can resolve spontaneously or with conservative treatment. However, up to 10% of the patients still do not respond to the conservative treatment, making the operative treatment still needed. Yet, the best approach remains controversial, which leaves the option to the individual surgeon’s experience and ease of the procedure. Our study aims to objectively find the difference in the outcome of the operative modalities qualitatively and quantitatively. Methods: This study was performed and reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Guideline where the protocol was registered PROSPERO [ID: CRD42022339650]. OCEBM level I-IV evidence studies were discovered using Boolean search strings that were created according to the patient, intervention, comparison, and outcomes of the study in three databases. Study quality was assessed with the Cochrane RoB tool and MINORS score. The success rate from operative modalities becomes the main outcome of the current study. Results: Forty-six studies were included in the study after a comprehensive literature search was done. From the analysis of 1944 elbows in three different groups, we found that arthroscopic surgery has the highest success rate (91.9%) compared to percutaneous (90.6%) and open (82.7%) lateral epicondylitis surgery with a change in mean pain score of 5.54, 4.90, and 3.63 respectively. The functional outcome improved according to DASH, in the arthroscopic group (51.51 to 15.47), the percutaneous group (44.90 to 10.47), and the open group (53.55 to 16.13). The overall improvement was also found in the MAYO score, in the arthroscopic group (55.12 to 64.70), in the percutaneous group (56.31 to 87.65), and the open group (64 to 93.37). Conclusion: Among the three different modalities of lateral epicondylitis surgery, arthroscopic surgery has the highest rate of success with the highest mean difference in pain score. Every surgical outcome also has an overall improvement in functional outcome scores.
    Type of Medium: Online Resource
    ISSN: 2325-9671 , 2325-9671
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2706251-X
    SSG: 31
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  • 7
    Online Resource
    Online Resource
    SAGE Publications ; 2023
    In:  Orthopaedic Journal of Sports Medicine Vol. 11, No. 2_suppl ( 2023-01-01), p. 2325967121S0087-
    In: Orthopaedic Journal of Sports Medicine, SAGE Publications, Vol. 11, No. 2_suppl ( 2023-01-01), p. 2325967121S0087-
    Abstract: One of the most frequent musculoskeletal disorders in adults is osteoarthritis. occurs due to degenerative processes in the joints, through wear and tear mechanism, especially in the articular cartilage. The treatment options for osteoarthritis are classified into symptomatic therapy and disease modification therapy. However, many people who suffer from osteoarthritis have limitations in their daily activities, thus preventing them from modifying their lifestyles. Many types of exercise exist, yet the best exercise for symptomatic osteoarthritis hasn’t been found. In daily practices, Moderate Intensity Continuous Training (MICT) is the most recommended and commonly performed type of exercise performed by patients with OA because MICT has a range of cardiovascular health benefits and maintains body weight. However, MICT may not provide enough stimulus to increase lower muscle mass and strength, articular changes that contribute to the pain, stiffness, and functional limitations seen in patients with knee OA. Some new studies found that High-Intensity Interval Training (HIIT) is more efficient than MICT as a classic exercise after six to eight weeks of exercise. HIIT in symptomatic osteoarthritis can significantly improve a patient’s fitness, visceral fats, and symptoms. HIIT can be a treatment option in resolving symptomatic knee osteoarthritis.
    Type of Medium: Online Resource
    ISSN: 2325-9671 , 2325-9671
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2706251-X
    SSG: 31
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  • 8
    Online Resource
    Online Resource
    Springer Science and Business Media LLC ; 2023
    In:  European Journal of Orthopaedic Surgery & Traumatology Vol. 33, No. 6 ( 2023-02-15), p. 2645-2654
    In: European Journal of Orthopaedic Surgery & Traumatology, Springer Science and Business Media LLC, Vol. 33, No. 6 ( 2023-02-15), p. 2645-2654
    Type of Medium: Online Resource
    ISSN: 1432-1068
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
    detail.hit.zdb_id: 1478935-8
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  • 9
    Online Resource
    Online Resource
    SAGE Publications ; 2023
    In:  Orthopaedic Journal of Sports Medicine Vol. 11, No. 2_suppl ( 2023-01-01), p. 2325967121S0086-
    In: Orthopaedic Journal of Sports Medicine, SAGE Publications, Vol. 11, No. 2_suppl ( 2023-01-01), p. 2325967121S0086-
    Abstract: Rotator cuff tear is one of the most common disorders in orthopedic surgery. When conservative treatment fails, arthroscopic rotator cuff repair has become the most common procedure to achieve a functional shoulder. Objectives: The articles on return to activities following arthroscopic rotator cuff repair have not been collectively analyzed and investigated. We aimed to review systematically and perform a meta-analysis of studies on the return to activities which consist of the return to work, return to sports, and return to daily activities following arthroscopic rotator cuff repair. Methods: Articles regarding return-to-activities were systematically searched using databases of PubMed, MEDLINE via EBSCO, ScienceDirect, and ProQuest. The review was done according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Guideline. The study protocol was registered in the PROSPERO International Prospective Register of Systematic Reviews [ID: CRD42022318293]. Studies with a level of evidence 1-4 that examined the rate of return to activities after arthroscopic rotator cuff repair were included and analyzed. Results: Fifteen studies published between 2005 and 2021 were included, with 1065 patients. The patient populations are workers and athletes. The meta-analysis on the combined effect of a return to activities using the random-effects model was 88.5% (83.8% on return to work, 88.2% on return to sport, and 97.3% on return to daily activities). The mean duration for return to activities is 6.59 months. The return to activities is positively influenced by the female population, heavy workers, longer duration of symptoms, surgery in the dominant arm, and massive tear may have negatively affected the ability to RTA. Conclusion: As much as 88.5% of patients were able to return to activities after arthroscopic rotator cuff repair with a mean duration of 6.59 months. Preoperative factors may contribute to the rate and duration of return to sports. Clinical Relevance: Clinicians can educate the patients regarding the rate, duration, and factors that contribute to return to activities (return to work, sport, and daily activities) after arthroscopic surgery rotator cuff repair.
    Type of Medium: Online Resource
    ISSN: 2325-9671 , 2325-9671
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2706251-X
    SSG: 31
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  • 10
    Online Resource
    Online Resource
    SAGE Publications ; 2023
    In:  Orthopaedic Journal of Sports Medicine Vol. 11, No. 2_suppl ( 2023-01-01), p. 2325967121S0086-
    In: Orthopaedic Journal of Sports Medicine, SAGE Publications, Vol. 11, No. 2_suppl ( 2023-01-01), p. 2325967121S0086-
    Abstract: Anterior cruciate ligament (ACL) rupture was the most common injury that occurred in the knee. Reconstruction was the most common operative management used. After primary ACL reconstruction, a rerupture can be devastating. Several extraarticular procedures have been proposed to resolve rotatory instability, such as tenodesis. We determined to conduct a meta-analysis comparing ACL reconstruction (ACLR) with lateral extraarticular tenodesis (LET) using the modified Lemaire technique and evaluated the risk of failure or re-rupture rate and the outcome. Method: We conducted a meta-analysis based on The Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA). The search was conducted in June 2022 on several databases: PubMed, EBSCOHost, Scopus, ScienceDirect, and WileyOnline using Boolean operators focusing on PICO (Population, Intervention, Control, Outcome). Included studies will be extracted for characteristics such as author and study year, location, design, sample characteristics, failure (graft or clinical failure), and outcome (KOOS score, functional outcome, clinical outcome). Studies will be qualitatively and quantitatively evaluated using Review Manager 5.4 or equivalent. Result: Search was conducted and resulted in the five final studies with 797 patients. ACLR + LET has a lower risk of failure or re-rupture ratio than ACLR alone (RR= 0.44; 95% CI 0.26 – 0.75; I2=9%; p= 0.003). There were differences in the KOOS pain score, ADL score, sports score and QOL score with mean difference of 0.20 (95% CI 0.10, 0.30; I2=0%; p 〈 0.0001), -0.20 (95% CI -0.26, -0.13; I2=0%; p 〈 0.00001), 0.20 (95% CI 0.02, 0.38; I2=0%; p= 0.03), and 0.50 (95% CI 0.29, 0.71; I2=0%; p 〈 0.00001) respectively. Furthermore, there was a significant mean difference in the International Knee Documentation Committee score of 0.70 (95% CI 0.57, 0.83; I2=0%; p 〈 0.000001). However, there were no significant differences in Lysholm score, and Tegner score between groups. Conclusion: LET was considered adequate in adjunction to ACLR, to minimize rerupture rate, and to improve stability and laxity of the knee to improve clinical outcome
    Type of Medium: Online Resource
    ISSN: 2325-9671 , 2325-9671
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2706251-X
    SSG: 31
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