In:
Applied Organometallic Chemistry, Wiley, Vol. 36, No. 2 ( 2022-02)
Abstract:
Electrocatalytic water oxidation by transition metal complexes is an emerging area of research. Here, two cobalt(III) complexes [Co(ftsm)NH 3 ( o ‐phen)]·H 2 O ( 1 ) {ftsm = bis (5‐furan‐1,2,4‐triazole)‐3‐sulfinamide} and [Co(ptsm)NH 3 ( o ‐phen)]·CH 3 OH ( 2 ) {ptsm = bis (5‐phenyl‐1,2,4‐triazole)‐3‐sulfinamide} were synthesized and characterized by various spectroscopic and X‐ray crystallography techniques. Complexes 1 and 2 were found to have admirable electrocatalytic activity towards oxygen evolution reaction (OER). The Tafel slope values for GC/Nf‐Complex‐ 2 and GC/RuO 2 were 53 and 60 mV/dec, respectively. Consequently, complex 2 possesses a better water oxidation response than standard material RuO 2 . The ligands Haftt, Haptt, o ‐phen, and complexes 1 and 2 were also tested for their cytotoxicity against Dalton's lymphoma (DL) cells employing MTT assay and found to have significant cytotoxicity. The IC 50 values of Haftt, Haptt, mixed ligands Haftt + o ‐phen and Haptt + o ‐phen, and complexes 1 and 2 against DL cells were found to be 150, 400, 200, 450, 80, and 5 μM, respectively. The complexes were found to have minimal effect on normal cells. The remarkable IC 50 value for complex 2 shows that it can be utilized as a potential anticancer agent against DL cells.
Type of Medium:
Online Resource
ISSN:
0268-2605
,
1099-0739
Language:
English
Publisher:
Wiley
Publication Date:
2022
detail.hit.zdb_id:
1480791-9
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