In:
PPAR Research, Hindawi Limited, Vol. 2008 ( 2008), p. 1-18
Abstract:
Peroxisome proliferator-activated receptor gamma (PPAR γ ) is a multifunctional transcription factor with important regulatory roles in inflammation, cellular growth, differentiation, and apoptosis. PPAR γ is expressed in a variety of immune cells as well as in numerous leukemias and lymphomas. Here, we review recent studies that provide new insights into the mechanisms by which PPAR γ ligands influence hematological malignant cell growth, differentiation, and survival. Understanding the diverse properties of PPAR γ ligands is crucial for the development of new therapeutic approaches for hematological malignancies.
Type of Medium:
Online Resource
ISSN:
1687-4757
,
1687-4765
Language:
English
Publisher:
Hindawi Limited
Publication Date:
2008
detail.hit.zdb_id:
2237981-2
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