In:
Journal of Clinical Periodontology, Wiley, Vol. 42, No. 10 ( 2015-10), p. 914-921
Abstract:
Generalized aggressive periodontitis ( GAP ) is a severe and multifactorial disease in which a familial aggregation and a specific microbiological profile have been suggested. Thus, this case–control study evaluated the clinical and subgingival microbial profile of GAP subjects and their families compared to healthy families. Methods Fifteen families with parents presenting periodontal health and 15 with parents with a history of GAP were selected. Each family should have at least one child between 6 and 12 years old. Plaque index ( PI ), gingival index ( GI ), and periodontal probing depth ( PPD ), as well as P orphyromonas gingivalis , T annerella forsythia , and A ggregatibacter actinomycetemcomitans ( A a) amounts (by q PCR ), were assessed from all subjects. Results Children of GAP families showed a higher PI , GI , and PPD when compared to children of healthy families ( p ≤ 0.05). A higher frequency of detection and amounts of A a was observed in GAP children compared to children of healthy families ( p ≤ 0.05). Moreover, a significant association between A a amounts and gingival bleeding was observed in children ( p ≤ 0.05, r = 0.37). Conclusion Children from GAP families have worst clinical conditions, i.e. higher levels of PI , GI , and PPD , a more pathogenic microbiological profile, and the amount of A a are associated with a higher marginal inflammation.
Type of Medium:
Online Resource
ISSN:
0303-6979
,
1600-051X
DOI:
10.1111/jcpe.2015.42.issue-10
Language:
English
Publisher:
Wiley
Publication Date:
2015
detail.hit.zdb_id:
2026349-1
Permalink