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  • 1
    Online Resource
    Online Resource
    Neurological insights on two siblings with GM3 synthase deficiency due to novel compound heterozygous ST3GAL5 variants
    Elsevier BV ; 2023
    In:  Brain and Development Vol. 45, No. 5 ( 2023-05), p. 270-277
    Details
    In: Brain and Development, Elsevier BV, Vol. 45, No. 5 ( 2023-05), p. 270-277
    Type of Medium: Online Resource
    ISSN: 0387-7604
    URL: Article
    DOI: 10.1016/j.braindev.2023.01.002
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2023
    detail.hit.zdb_id: 1499913-4
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  • 2
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    消化管出血をきたし外科的切除を行った胃脂肪腫の2例
    Japan Gastrointestinal Endoscopy Society ; 2021
    In:  Progress of Digestive Endoscopy Vol. 98, No. 1 ( 2021-6-25), p. 88-90
    Details
    In: Progress of Digestive Endoscopy, Japan Gastrointestinal Endoscopy Society, Vol. 98, No. 1 ( 2021-6-25), p. 88-90
    Type of Medium: Online Resource
    ISSN: 1348-9844 , 2187-4999
    URL: Article
    DOI: 10.11641/pde.98.1_88
    Language: English
    Publisher: Japan Gastrointestinal Endoscopy Society
    Publication Date: 2021
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  • 3
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    Data_Sheet_1.docx
    Frontiers Media SA ; 2023
    In:  Frontiers in Medicine Vol. 10 ( 2023-5-22)
    Details
    In: Frontiers in Medicine, Frontiers Media SA, Vol. 10 ( 2023-5-22)
    Abstract: To investigate whether ivermectin inhibits SARS-CoV-2 proliferation in patients with mild-to-moderate COVID-19 using time to a negative COVID-19 reverse transcription-polymerase chain reaction (RT-PCR) test. Methods CORVETTE-01 was a double-blind, randomized, placebo-controlled study (August 2020–October 2021) conducted in Japan. Overall, 248 patients diagnosed with COVID-19 using RT-PCR were assessed for eligibility. A single oral dose of ivermectin (200  μg/kg) or placebo was administered under fasting. The primary outcome was time to a negative COVID-19 RT-PCR test result for SARS-CoV-2 nucleic acid, assessed using stratified log-rank test and Cox regression models. Results Overall, 112 and 109 patients were randomized to ivermectin and placebo, respectively; 106 patients from each group were included in the full analysis set (male [%], mean age: 68.9%, 47.9 years [ivermectin] ; 62.3%, 47.5 years [placebo]). No significant difference was observed in the occurrence of negative RT-PCR tests between the groups (hazard ratio, 0.96; 95% confidence interval [CI] 0.70–1.32; p  = 0.785). Median (95% CI) time to a negative RT-PCR test was 14.0 (13.0–16.0) and 14.0 (12.0–16.0) days for ivermectin and placebo, respectively; 82.1% and 84% of patients achieved negative RT-PCR tests, respectively. Conclusion In patients with COVID-19, single-dose ivermectin was ineffective in decreasing the time to a negative RT-PCR test. Clinical Trial Registration ClinicalTrials.gov , NCT04703205.
    Type of Medium: Online Resource
    ISSN: 2296-858X
    URL: Article
    URL: Article
    DOI: 10.3389/fmed.2023.1139046
    DOI: 10.3389/fmed.2023.1139046.s001
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2023
    detail.hit.zdb_id: 2775999-4
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  • 4
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    X-ray polarimeter with a transmission multilayer
    AIP Publishing ; 2010
    In:  Review of Scientific Instruments Vol. 81, No. 2 ( 2010-02-01)
    Details
    In: Review of Scientific Instruments, AIP Publishing, Vol. 81, No. 2 ( 2010-02-01)
    Abstract: We fabricated a novel x-ray polarimeter with a transmission multilayer and measured its performance with synchrotron radiation. A self standing multilayer with seven Mo/Si bilayers was installed with an incident angle of 45° in front of a back-illuminated CCD. The multilayer can be rotated around the normal direction of the CCD keeping an incident angle of 45°. This polarimeter can be easily installed along the optical axis of x-ray optics. By using the CCD as a photon counting detector with a moderate energy resolution, the polarization of photons in a designed energy band can be measured along with the image. At high photon energies, where the multilayer is transparent, the polarimeter can be used for imaging and spectroscopic observations. We confirmed a modulation factor of 45% with 45% and 17% transmission for P- and S-polarization, respectively.
    Type of Medium: Online Resource
    ISSN: 0034-6748 , 1089-7623
    URL: Article
    DOI: 10.1063/1.3294330
    Language: English
    Publisher: AIP Publishing
    Publication Date: 2010
    detail.hit.zdb_id: 209865-9
    detail.hit.zdb_id: 1472905-2
    SSG: 11
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  • 5
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    Effect of a decision aid on the choice of pregnant women whether to have epidural anesthesia or not during labor
    Public Library of Science (PLoS) ; 2020
    In:  PLOS ONE Vol. 15, No. 11 ( 2020-11-12), p. e0242351-
    Details
    In: PLOS ONE, Public Library of Science (PLoS), Vol. 15, No. 11 ( 2020-11-12), p. e0242351-
    Abstract: Decision aids (DAs) are useful in providing information for decision-making on using epidural anesthesia during birth. To date, there has been little development of DAs for Japanese pregnant women. Herein, we investigated the effect of a DA on the decision of pregnant women whether to have epidural anesthesia or not for labor during vaginal delivery. The primary outcome was changes in mean decision conflict score. Methods In this non-randomized controlled trial, 300 low-risk pregnant women in an urban hospital were recruited by purposive sampling and assigned to 2 groups: DA (intervention) and pamphlet (control) groups. Control enrollment was started first (until 150 women), followed by intervention enrollment (150 women). Pre-test and post-test scores were evaluated using the Decision Conflict Scale (DCS) for primary outcome, knowledge of epidural anesthesia and satisfaction with decision making for secondary outcomes, and decision of anesthesia usage (i.e., with epidural anesthesia, without epidural anesthesia, or undecided). Results Women in the DA group (n = 149: 1 excluded because she did not return post-test questionnaire) had significantly lower DCS score than those in the pamphlet group (n = 150) (DA: -8.41 [SD 8.79] vs. pamphlet: -1.69 [SD 5.91] , p 〈 .001). Knowledge of epidural anesthesia and satisfaction with decision-making scores of women who used the DA were significantly higher than those of women who used the pamphlet (p 〈 .001). Women in the DA group showed a significantly lower undecided rate than those in the pamphlet group. The number of undecided women in the DA group significantly decreased from 30.2% to 6.1% (p 〈 .001), whereas that in the pamphlet group remained largely unchanged from 40.7% to 38.9%. Conclusion This study indicates that a DA can be useful in helping women make a decision whether to have epidural anesthesia or not for labor during vaginal delivery.
    Type of Medium: Online Resource
    ISSN: 1932-6203
    URL: Article
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    DOI: 10.1371/journal.pone.0242351
    DOI: 10.1371/journal.pone.0242351.g001
    DOI: 10.1371/journal.pone.0242351.g002
    DOI: 10.1371/journal.pone.0242351.g003
    DOI: 10.1371/journal.pone.0242351.t001
    DOI: 10.1371/journal.pone.0242351.t002
    DOI: 10.1371/journal.pone.0242351.t003
    DOI: 10.1371/journal.pone.0242351.s001
    DOI: 10.1371/journal.pone.0242351.s002
    DOI: 10.1371/journal.pone.0242351.s003
    DOI: 10.1371/journal.pone.0242351.s004
    DOI: 10.1371/journal.pone.0242351.r001
    DOI: 10.1371/journal.pone.0242351.r002
    DOI: 10.1371/journal.pone.0242351.r003
    DOI: 10.1371/journal.pone.0242351.r004
    Language: English
    Publisher: Public Library of Science (PLoS)
    Publication Date: 2020
    detail.hit.zdb_id: 2267670-3
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  • 6
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    A Decision Aid for Postpartum Adolescent Family Planning: A Quasi-Experimental Study in Tanzania
    MDPI AG ; 2023
    In:  International Journal of Environmental Research and Public Health Vol. 20, No. 6 ( 2023-03-10), p. 4904-
    Details
    In: International Journal of Environmental Research and Public Health, MDPI AG, Vol. 20, No. 6 ( 2023-03-10), p. 4904-
    Abstract: Background: We evaluated the effects of our postpartum Green Star family planning decision aid on the decisional conflict, knowledge, satisfaction, and uptake of long-acting reversible contraception among pregnant adolescents in Tanzania. Methods: We used a facility-based pre–post quasi-experimental design. The intervention arm received routine family planning counseling and the decision aid. The control received only routine family planning counseling. The primary outcome was the change in decisional conflict measured using the validated decision conflict scale (DCS). The secondary outcomes were knowledge, satisfaction, and contraception uptake. Results: We recruited 66 pregnant adolescents, and 62 completed this study. The intervention group had a lower mean score difference in the DCS than in the control (intervention: −24.7 vs. control: −11.6, p 〈 0.001). The mean score difference in knowledge was significantly higher in the intervention than in the control (intervention: 4.53 vs. control: 2.0, p 〈 0.001). The mean score of satisfaction was significantly higher in the intervention than in the control (intervention: 100 vs. control: 55.8, p 〈 0.001). Contraceptive uptake was significantly higher in the intervention [29 (45.3%)] than in the control [13 (20.3%)] (p 〈 0.001). Conclusion: The decision aid demonstrated positive applicability and affordability for pregnant adolescents in Tanzania.
    Type of Medium: Online Resource
    ISSN: 1660-4601
    URL: Article
    DOI: 10.3390/ijerph20064904
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2175195-X
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  • 7
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    Updated Decision Aid Enabling Women to Choose between with or without Epidural Analgesia during Childbirth, and Confirmation of Validity
    MDPI AG ; 2023
    In:  International Journal of Environmental Research and Public Health Vol. 20, No. 11 ( 2023-06-02), p. 6042-
    Details
    In: International Journal of Environmental Research and Public Health, MDPI AG, Vol. 20, No. 11 ( 2023-06-02), p. 6042-
    Abstract: Background: The use of a decision aid for choosing whether to have or not have anesthesia during childbirth has been shown to increase both knowledge about birth and the proportion of women who made their own decisions compared with women who did not use a decision aid. Herein, we updated the first version of our decision aid into a second version and evaluated this updated decision aid. We evaluated the face validity and content appropriateness of the updated decision aid developed to enhance the ability of women to choose between childbirth with or without epidural analgesia. Methods: This was a descriptive study based on a literature review of updated information for addition to the first version. PubMed and Cochrane Library were searched from 2003 to May 2021. Thereafter, obstetricians, anesthesiologists, and midwives were asked to respond to a questionnaire regarding the face validity and content appropriateness of the updated decision aid regarding whether it meets the IPDASi (Version 4.0) quality standards. Results: One obstetrician, one anesthesiologist, and three midwives who had performed epidural anesthesia for at least three years responded to the questionnaire. The responses to the evaluation items of face validity (i.e., style and clarity) were positive. There were 38 specific comments regarding content appropriateness classified into seven categories: “addition or revision of text”, “unification of expressions”, “need for explanation/information”, “lack of evidence”, “potential to mislead”, “questionable”, and “structure”. Conclusion: The face validity and content appropriateness of the updated decision aid was confirmed. The next step is evaluation of the updated decision aid by pregnant women who give birth.
    Type of Medium: Online Resource
    ISSN: 1660-4601
    URL: Article
    DOI: 10.3390/ijerph20116042
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2175195-X
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  • 8
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    妊娠糖尿病のセルフマネジメント行動を促進・阻害する要因：女性の声を聴く
    Japan Academy of Nursing Science ; 2022
    In:  Journal of Japan Academy of Nursing Science Vol. 42, No. 0 ( 2022), p. 642-651
    Details
    In: Journal of Japan Academy of Nursing Science, Japan Academy of Nursing Science, Vol. 42, No. 0 ( 2022), p. 642-651
    Type of Medium: Online Resource
    ISSN: 0287-5330 , 2185-8888
    URL: Article
    DOI: 10.5630/jans.42.642
    Language: English
    Publisher: Japan Academy of Nursing Science
    Publication Date: 2022
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  • 9
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    Postpartum Green Star family planning decision aid for pregnant adolescents in Tanzania: a qualitative feasibility study
    Springer Science and Business Media LLC ; 2021
    In:  Reproductive Health Vol. 18, No. 1 ( 2021-12)
    Details
    In: Reproductive Health, Springer Science and Business Media LLC, Vol. 18, No. 1 ( 2021-12)
    Abstract: The use of a decision aid in clinical settings has been beneficial. It informs and educates patients about the available treatment options that can help them reduce decision-making conflicts related to feeling uninformed compared with routine care. There is a scarcity of published data about using a decision aid during family planning counseling with postpartum women focusing on long-acting reversible contraception in Tanzania. Therefore, we developed a “postpartum Green Star family planning decision aid” and assessed its feasibility. The study outcomes were practicality, usefulness, and acceptability perceived by pregnant adolescents and nurses/midwives. Methods We used an exploratory qualitative in-depth interview involving six nurses/midwives with three or more years of experience in family planning services and 12 pregnant adolescents aged 15–19 years. Purposive sampling was used to select the participants, and selection relied on the saturation principle of data collection. We used a semi-structured interview guide translated into the Kiswahili language. Data were transcribed and analyzed following inductive content analysis. Results The amount of information presented was just right, with the time of reading the data ranging from 20 min to 1 h. The study participants perceived the flow of information to be good, with small significant changes suggested. Kiswahili language was used and reported to be appropriate and well elaborated. However, a few words were told to be rephrased to reduce ambiguity. The nurses/midwives said that the decision aid included most of the vital information the participants wanted to know during their family planning counseling. Pregnant adolescents stated that the decision aid improved their knowledge and provided new details on the long-acting reversible contraception methods (intrauterine copper devices and implants) offered immediately after childbirth. The participants stated that the decision aid addressed long-acting reversible contraception methods’ benefits and side effects and dispelled myths and misconceptions. The study participants considered the decision aid helpful in complementing the family planning counseling offered and improving pregnant adolescents’ knowledge. Conclusion The postpartum Green Star family planning decision aid was practical, useful, and acceptable in enhancing the objectivity of counseling about long-acting reversible contraception methods. It improved the knowledge of pregnant adolescents in Tanzania about the available contraception methods (i.e., the use of intrauterine copper devices and implants), which can be immediately used postpartum. Further research is needed to assess the effects of the decision aid on long-acting reversible contraception postpartum uptake among pregnant adolescents in Tanzania.
    Type of Medium: Online Resource
    ISSN: 1742-4755
    URL: Article
    DOI: 10.1186/s12978-021-01216-6
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2021
    detail.hit.zdb_id: 2149029-6
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  • 10
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    Women's experiences and perceptions of women‐centered care and respectful care during facility‐based childbirth: A meta‐synthesis
    Wiley ; 2022
    In:  Japan Journal of Nursing Science Vol. 19, No. 3 ( 2022-07)
    Details
    In: Japan Journal of Nursing Science, Wiley, Vol. 19, No. 3 ( 2022-07)
    Abstract: The World Health Organization has recommended intrapartum care for a positive childbirth experience through respectful care based on women‐centered care. This study aimed to explore women's experiences of facility‐based childbirth to gain insights into their perceptions of women‐centered care, including humanized childbirth and respectful maternity care during intrapartum care. Methods Used the Joanna Briggs Institute method as the framework for this meta‐synthesis, we searched the PubMed, EMBASE, CINAHL, PsycINFO, and LILCAS databases, and included qualitative studies and interviews of women's experiences and perceptions of women‐centered care during facility‐based childbirth published from 1990 to 2020 in English. Study quality was assessed using the Critical Appraisal Skills Programme checklist. NVivo software was used for data extraction and synthesis. Results There were 22 studies from 19 countries that met the established inclusion criteria. Five categories of experiences of facility‐based childbirth and perceptions of women‐centered care from the synthesized voices of women were generated: (i) value of women through childbirth; (ii) overwhelmed by unpleasant childbearing experiences; (iii) a sense of being respected and valued; (iv) a sense of being disrespected and abused; and (v) inadequate systems and resources. Our meta‐synthesis indicated that respectful and helpful interaction between women and healthcare providers produced positive perceptions among women. Conclusions This study emphasizes the importance of respectful interactions and intrapersonal experiences. Strong systems and positive environments lead to positive interactions between women and healthcare providers. Future studies need to consider cultural and economic differences in women‐centered care and respectful care for childbirth in different contexts.
    Type of Medium: Online Resource
    ISSN: 1742-7932 , 1742-7924
    URL: Issue
    URL: Article
    DOI: 10.1111/jjns.v19.3
    DOI: 10.1111/jjns.12475
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 2156618-5
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