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  • 1
    In: Cancer, Wiley, Vol. 126, No. 21 ( 2020-11), p. 4761-4769
    Abstract: Decision making regarding the initial treatment of women diagnosed with breast cancer is complicated, especially for young women with childcare responsibilities. The current study finds that having young‐aged children is strongly associated with either undergoing mastectomy or omitting radiotherapy after lumpectomy.
    Type of Medium: Online Resource
    ISSN: 0008-543X , 1097-0142
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 1479932-7
    detail.hit.zdb_id: 2599218-1
    detail.hit.zdb_id: 2594979-2
    detail.hit.zdb_id: 1429-1
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  • 2
    Online Resource
    Online Resource
    Oxford University Press (OUP) ; 2023
    In:  JNCI: Journal of the National Cancer Institute Vol. 115, No. 3 ( 2023-03-09), p. 295-302
    In: JNCI: Journal of the National Cancer Institute, Oxford University Press (OUP), Vol. 115, No. 3 ( 2023-03-09), p. 295-302
    Abstract: There is a lack of evidence from nationwide samples on the disparity of initiating immune checkpoint inhibitors (ICIs) after metastatic lung cancer diagnosis. Methods We identified metastatic lung cancer patients diagnosed between 2015 and 2020 from a large, nationwide commercial claims database. We analyzed the time from metastatic lung cancer diagnosis to ICI therapy using Cox proportional hazard models. Independent variables included county-level measures (quintiles of percentage of racialized population, quintiles of percentage of population below poverty, urbanity, and density of medical oncologists) and patient characteristics (age, sex, Charlson comorbidity index, Medicare Advantage, and year of diagnosis). All tests were 2-sided. Results A total of 17 022 patients were included. Counties with a larger proportion of racialized population appeared to be more urban, have a greater percentage of its residents in poverty, and have a higher density of medical oncologists. In Cox analysis, the adjusted hazard ratio of the second, third, fourth, and highest quintile of percentage of racialized population were 0.89 (95% confidence interval [CI] = 0.82 to 0.98), 0.85 (95% CI = 0.78 to 0.93), 0.78 (95% CI = 0.71 to 0.86), and 0.71 (95% CI = 0.62 to 0.81), respectively, compared with counties in the lowest quintile. The slower ICI therapy initiation was driven by counties with the highest percentage of Hispanic population and other non-Black racialized groups. Conclusions Commercially insured patients with metastatic lung cancer who lived in counties with greater percentage of racialized population had slower initiation of ICI therapy after lung cancer diagnosis, despite greater density of oncologists in their neighborhood.
    Type of Medium: Online Resource
    ISSN: 0027-8874 , 1460-2105
    RVK:
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2023
    detail.hit.zdb_id: 2992-0
    detail.hit.zdb_id: 1465951-7
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  • 3
    Online Resource
    Online Resource
    American Society of Clinical Oncology (ASCO) ; 2022
    In:  Journal of Clinical Oncology Vol. 40, No. 16_suppl ( 2022-06-01), p. 1595-1595
    In: Journal of Clinical Oncology, American Society of Clinical Oncology (ASCO), Vol. 40, No. 16_suppl ( 2022-06-01), p. 1595-1595
    Abstract: 1595 Background: The use of telemedicine among cancer patients remains limited. Because of the COVID-19 pandemic, CMS expansion of telehealth with 1135 waiver was enacted in March 2020, broadening the opportunities to provide patient care using telemedicine. This study examined the impact of the CMS expansion on the use of telemedicine among cancer patients. Methods: We identified newly diagnosed patients with 5 common cancers (breast, prostate, lung, colorectal, and lymphoma) between 3/2019 and 12/2020 from Optum’s de-identified Clinformatics Data Mart Database. Patients who had 6 months of full enrollment (3 months before and 3 months after the first [index] cancer diagnosis date), had cancer claims on 3 separate dates within 3 months of the index date for the specific cancer diagnosis, and no prior history of cancer were included. We defined telemedicine use as patients who had a telemedicine procedure code within 1 month of their index diagnosis and had the cancer diagnosis on the telemedicine claim. We conducted an interrupted time series analysis to examine the impact of CMS expansion on telemedicine use. A multivariable logistic regression model was used to identify factors associated with telemedicine use during the post-expansion period. Results: Of 96,632 patients included, the average crude rate of telemedicine use was 0.12% before and 14.2% after the expansion in March 2020 (see Table). There was a significant impact of expansion on telemedicine use (21% increase; p 〈 0.001). The peak rate (adjusted) was 28% in April 2020, decreasing and plateauing in July/August 2020, with rates staying in the range of 10-12% between August and December 2020. During the post-expansion period, lymphoma, prostate, and lung cancer patients (adjusted rates: 14.6%, 15.7%, and 15.9%, respectively) were more likely to use telemedicine compared to patients who had breast (12.7%) or colorectal (12.3%) cancer. Patients who were older (adjusted rates: ≥65 years, 13.8%; 50-64, 14.2%; 20-49, 18.6%), Black (12.4% vs 14.4% for White, 15.5% for Hispanic and 16.6% for Asian), resided in East South Central census division (8.4% vs 23.5% in New England) and had Medicare (12.2% vs 20.3% for commercial insurance) were less likely to use telemedicine (all p 〈 .001). Conclusions: After the CMS telehealth expansion, the use of telemedicine among newly diagnosed cancer patients increased significantly. Telemedicine use varied by patient age, geographic location, race/ethnicity, and payer. Further research is needed to understand the pattern of telemedicine use.[Table: see text]
    Type of Medium: Online Resource
    ISSN: 0732-183X , 1527-7755
    RVK:
    RVK:
    Language: English
    Publisher: American Society of Clinical Oncology (ASCO)
    Publication Date: 2022
    detail.hit.zdb_id: 2005181-5
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  • 4
    Online Resource
    Online Resource
    American Society of Clinical Oncology (ASCO) ; 2023
    In:  JCO Oncology Practice Vol. 19, No. 7 ( 2023-07), p. 446-455
    In: JCO Oncology Practice, American Society of Clinical Oncology (ASCO), Vol. 19, No. 7 ( 2023-07), p. 446-455
    Abstract: Use of preoperative breast MRI increased 25% from 2008 to 2020, despite inconclusive clinical benefit.
    Type of Medium: Online Resource
    ISSN: 2688-1527 , 2688-1535
    Language: English
    Publisher: American Society of Clinical Oncology (ASCO)
    Publication Date: 2023
    detail.hit.zdb_id: 3005549-0
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  • 5
    Online Resource
    Online Resource
    American Society of Clinical Oncology (ASCO) ; 2023
    In:  Journal of Clinical Oncology Vol. 41, No. 16_suppl ( 2023-06-01), p. 1607-1607
    In: Journal of Clinical Oncology, American Society of Clinical Oncology (ASCO), Vol. 41, No. 16_suppl ( 2023-06-01), p. 1607-1607
    Abstract: 1607 Background: The COVID-19 public health emergency (PHE), declared on January 31, 2020, relaxed many telemedicine restrictions. Yet there remains wide variation across states on the coverage and reimbursement of telemedicine services and rules to permit practicing across state lines. Research has shown expanded access to telemedicine is beneficial to cancer patients, making it important to understand the relationship between state policies and the use of telemedicine. Methods: We identified privately insured non-elderly patients newly diagnosed with any of five common cancers (female breast, prostate, lung, colorectal, and lymphoma) between March 2019 and March 2021 from Optum Clinformatics Data Mart. We characterized state telehealth policies by parity status (coverage & payment parity, coverage parity only, and none) and rules for cross-state practice (allowed with vs. without limitations). We applied interrupted time series analysis to examine the trend of telemedicine use before and after the declaration of COVID-19 PHE and conducted multivariable logistic regression to examine the association between state policies and telemedicine use while controlling for other confounders. Results: Of the 10,813 privately insured non-elderly patients, the adjusted rate of telemedicine use was 23.6%. The average age was 53.2 (SD = 9.24). Race/ethnicity distribution was 71.20% non-Hispanic White, 10.07% non-Hispanic Black, 8.56% Hispanics, 3.77% Asians, and 6.39% others. Lymphoma, female breast, colorectal, lung, and prostate cancer accounted for 10.55%, 46.55%, 13.27%, 7.56%, and 22.07% of patients. A sharp increase was observed early on (from 32.4% in March 2020 to 42.5% in April 2020), followed by a steady decline, down to 〈 15% by March 2021. Compared to patients residing in states with coverage and payment parity, those in states with only coverage parity and no parity were significantly less likely to use telemedicine (OR = 0.79, 95% CI: [0.71 – 0.88]; OR = 0.77, [0.68 – 0.87] ). Patients residing in states with more restrictions/regulations on cross-state practice were significantly less likely to use telemedicine (OR = 0.84, [0.76 – 0.93]) than those in states that were less restrictive. Other factors predicting lower likelihood of telemedicine use included older age (OR = 0.69 [0.62-0.77] for age 50-64 vs. 20-49), non-Hispanic Black (OR = 0.84 [0.72 – 0.98] vs. non-Hispanic White), colorectal cancer (OR = 0.82 [0.70 – 0.96] vs. female breast), and more recent diagnosis. Conclusions: With the approaching end of COVID-19 PHE, states are deciding whether to permanently relax certain telemedicine policies or return to existing more restrictive policies. Our study suggests patients residing in states that move toward less generous parity and more restrictive cross-state practice rules may be less likely to benefit from telemedicine.
    Type of Medium: Online Resource
    ISSN: 0732-183X , 1527-7755
    RVK:
    RVK:
    Language: English
    Publisher: American Society of Clinical Oncology (ASCO)
    Publication Date: 2023
    detail.hit.zdb_id: 2005181-5
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  • 6
    Online Resource
    Online Resource
    Oxford University Press (OUP) ; 2023
    In:  JNCI Cancer Spectrum
    In: JNCI Cancer Spectrum, Oxford University Press (OUP)
    Abstract: Telehealth restrictions were relaxed under the COVID-19 public health emergency (PHE). We examined telehealth use before and during the pandemic among patients with newly diagnosed cancers and the association between state policies and telehealth use. Methods The study cohort was constructed from Optum’s de-identified Clinformatics®Data Mart and included patients with lymphoma, female breast, colorectal, prostate, and lung cancer diagnosed between 3/1/2019 and 3/31/2021. We performed an interrupted time series analysis to examine the trend of cancer-related telehealth use within one month of diagnosis relative to the timing of the COVID-19 PHE and multivariable logistic regressions to examine factors, specifically state parity laws and regulations on cross-state practice, associated with telehealth. Results Of 110,461 patients, the rate of telehealth use peaked at 33.4% in 4/2020, then decreased to 12-15% between 9/2020 and 3/2021. Among the 53,982 patients diagnosed since 3/2020, telehealth use was significantly lower for privately insured patients residing in states with coverage-only parity or no/unspecified parity than those in states with coverage and payment parity (adjusted rate: 20.2%, 19.1%, and 23.3%, respectively). The adjusted rate was lower for patients in states with cross-state telehealth policy limitations than those in states without restrictions (14.9% vs. 17.8%). Conclusions Telehealth use by patients diagnosed with cancer during the pandemic was higher among those living in states with more generous parity and less restrictive rules for cross-state practice. Policy makers contemplating whether to permanently relax certain telehealth policies must consider the impact on vulnerable patient populations who can benefit from telehealth.
    Type of Medium: Online Resource
    ISSN: 2515-5091
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2023
    detail.hit.zdb_id: 2975772-1
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  • 7
    Online Resource
    Online Resource
    American Society of Clinical Oncology (ASCO) ; 2022
    In:  Journal of Clinical Oncology Vol. 40, No. 16_suppl ( 2022-06-01), p. 1583-1583
    In: Journal of Clinical Oncology, American Society of Clinical Oncology (ASCO), Vol. 40, No. 16_suppl ( 2022-06-01), p. 1583-1583
    Abstract: 1583 Background: Checkpoint inhibitors are transforming cancer care. However, the high prices of these medicines raise concerns over their affordability and disparity in use. The objective of this study is to describe the disparity in initiating checkpoint inhibitors and examine patient- and area-level factors associated with delayed initiation. Methods: This study is a retrospective cohort study using Optum data. We identified commercially insured patients newly diagnosed with metastatic lung cancer and melanoma since the introduction of checkpoint inhibitors in these cancers (lung cancer cohort: diagnosed between January 2015 and December 2020; melanoma cohort: diagnosed between January 2011 and December 2020). Time from metastatic cancer diagnosis to initiating checkpoint inhibitors was analyzed using Cox proportional hazard models. Independent variables included county-level measures (percentage of black population, percentage of Hispanic population, percentage of other minority, percentage of population living below poverty line, rurality, number of medical oncologist per population, and having a National Cancer Institute designated cancer center) and patient-level characteristics (age, sex, Charlson comorbidity index, any dual eligibility, Medicare Advantage, and year of diagnosis). We clustered standard errors at the county level. Results: The percentage of metastatic lung cancer and metastatic melanoma patients on checkpoint inhibitors increased from 23% to 52% from 2015 to 2020 and from 22% to 58% from 2011 to 2020. Counties with greater percentage of black, Hispanics, and other minorities were high urban with greater density of medical oncologists and NCI-designated cancer centers. However, greater percentage of Hispanic population in a county was associated with significantly slower initiation of checkpoint inhibitors for both the lung cancer and the melanoma cohorts (hazard ratios [HR]: 0.937 and 0.946, respectively; p-values: 〈 0.001 and 0.014, respectively). Percentage of other minority population in a county was associated with slower initiation for metastatic lung cancer (HR: 0.983; p-value: 〈 0.001). No other county-level factors had a significant coefficient from the multivariate Cox models. In terms of patient-level characteristics, older age, female, more comorbidities, any dual eligibility, and Medicare Advantage were associated with significantly slower initiation for the lung cancer cohort and older age and female were associated with significantly slower initiation for the melanoma cohort. Conclusions: Commercially insured metastatic lung cancer and melanoma patients who lived in counties with greater percentage of Hispanic population had slower initiation of checkpoint inhibitors after their cancer diagnosis, despite the fact that those counties had greater density of medical oncologists and NCI-designated cancer centers.
    Type of Medium: Online Resource
    ISSN: 0732-183X , 1527-7755
    RVK:
    RVK:
    Language: English
    Publisher: American Society of Clinical Oncology (ASCO)
    Publication Date: 2022
    detail.hit.zdb_id: 2005181-5
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  • 8
    In: JNCI: Journal of the National Cancer Institute, Oxford University Press (OUP), Vol. 115, No. 10 ( 2023-10-09), p. 1115-1120
    Type of Medium: Online Resource
    ISSN: 0027-8874 , 1460-2105
    RVK:
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2023
    detail.hit.zdb_id: 2992-0
    detail.hit.zdb_id: 1465951-7
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  • 9
    Online Resource
    Online Resource
    Harborside Press, LLC ; 2021
    In:  Journal of the National Comprehensive Cancer Network Vol. 19, No. 4 ( 2021-04), p. 421-431
    In: Journal of the National Comprehensive Cancer Network, Harborside Press, LLC, Vol. 19, No. 4 ( 2021-04), p. 421-431
    Abstract: Background: Understanding the sources of variation in the use of high-cost technologies is important for developing effective strategies to control costs of care. Palliative radiation therapy (RT) is a discretionary treatment and its use may vary based on patient and clinician factors. Methods: Using data from the SEER-Medicare linked database, we identified patients diagnosed with metastatic lung, prostate, breast, and colorectal cancers in 2010 through 2015 who received RT, and the radiation oncologists who treated them. The costs of radiation services for each patient over a 90-day episode were calculated, and radiation oncologists were assigned to cost quintiles. The use of advanced technologies (eg, intensity-modulated radiation, stereotactic RT) and the number of RT treatments (eg, any site, bone only) were identified. Multivariable random-effects models were constructed to estimate the proportion of variation in the use of advanced technologies and extended fractionation ( 〉 10 fractions) that could be explained by patient fixed effects versus physician random effects. Results: We identified 37,361 patients with metastatic lung cancer, 3,684 with metastatic breast cancer, 5,323 with metastatic prostate cancer, and 8,726 with metastatic colorectal cancer, with 34%, 27%, 22%, and 9% receiving RT within the first year, respectively. The use of advanced technologies and extended fractionation was associated with higher costs of care. Compared with the patient case-mix, physician variation accounted for a larger proportion of the variation in the use of advanced technologies for palliative RT and the use of extended fractionation. Conclusions: Differences in radiation oncologists’ practice and choices, rather than differences in patient case-mix, accounted for a greater proportion of the variation in the use of advanced technologies and high-cost radiation services.
    Type of Medium: Online Resource
    ISSN: 1540-1405 , 1540-1413
    Language: Unknown
    Publisher: Harborside Press, LLC
    Publication Date: 2021
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  • 10
    Online Resource
    Online Resource
    Springer Science and Business Media LLC ; 2019
    In:  Journal of General Internal Medicine Vol. 34, No. 9 ( 2019-09-15), p. 1766-1774
    In: Journal of General Internal Medicine, Springer Science and Business Media LLC, Vol. 34, No. 9 ( 2019-09-15), p. 1766-1774
    Type of Medium: Online Resource
    ISSN: 0884-8734 , 1525-1497
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2019
    detail.hit.zdb_id: 2006784-7
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