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  • 1
    Online Resource
    Online Resource
    Frequency and prevalence of clinical conditions and therapeutic drugs used in dog and cat at Teaching Veterinary Hospital, Chattogram Veterinary and Animal Sciences University
    ScopeMed ; 2020
    In:  Journal of Advanced Veterinary and Animal Research Vol. 7, No. 1 ( 2020), p. 156-
    Details
    In: Journal of Advanced Veterinary and Animal Research, ScopeMed, Vol. 7, No. 1 ( 2020), p. 156-
    Type of Medium: Online Resource
    ISSN: 2311-7710
    URL: Journal
    URL: Article
    DOI: 10.5455/javar.
    DOI: 10.5455/javar.2020.g405
    Language: Unknown
    Publisher: ScopeMed
    Publication Date: 2020
    detail.hit.zdb_id: 2766493-4
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  • 2
    Online Resource
    Online Resource
    First report of canine parvovirus molecular detection in Bangladesh
    Veterinary World ; 2021
    In:  Veterinary World Vol. 14, No. 4 ( 2021-4-29), p. 1038-1043
    Details
    In: Veterinary World, Veterinary World, Vol. 14, No. 4 ( 2021-4-29), p. 1038-1043
    Abstract: Background and Aim: Canine parvovirus (CPV) is the most important cause of mortality in dogs in many parts of the world. Clinical cases exhibit characteristic signs, including foul-smelling bloody diarrhea, vomiting, fever, and dehydration. This study assessed field and vaccine variants of parvovirus in the Chattogram metropolitan area, Bangladesh. The investigation also aimed to identify risk factors for this disease. This research is the first to identify the presence of CPV in Bangladesh through molecular examination. Materials and Methods: From October to December 2019, a total of 100 dogs were included in the study. Rectal swabs were taken from all dogs. Twenty dogs showed clinical signs of parvovirus. All clinically affected animals along with 20 randomly selected healthy dogs were tested using amplification refractory mutation system (ARMS)-polymerase chain reaction (PCR) to identify variants from the samples. Logistic regression model analysis was performed to determine the possible risk factors for CPV. Results: ARMS-PCR showed the presence of all three variants, CPV2a, CPV2b, and CPV2c, in clinically ill dogs, and vaccines available in the study area showed either CPV2a or CPV2b strain. The CPV2c variants showed a higher incidence than the other variants. All apparently healthy animals tested were molecularly negative. Multivariable logistic regression model (generalized linear mixed model) indicated that exotic breeds were 3.83 times more likely to be infected by CPV than local breeds. Furthermore, dogs reared in semi-intensive and extensive management systems were 3.64 and 3.79 times more likely to be infected, respectively, than those reared in an intensive management system. Conclusion: These findings provide practitioners and pet owners information on the occurrence of different variants and help design effective prevention strategies for CPV infection.
    Type of Medium: Online Resource
    ISSN: 2231-0916 , 0972-8988
    URL: Issue
    URL: Journal
    URL: Article
    DOI: 10.14202/vetworld.2021.4
    DOI: 10.14202/vetworld.
    DOI: 10.14202/vetworld.2021.1038-1043
    Language: English
    Publisher: Veterinary World
    Publication Date: 2021
    detail.hit.zdb_id: 2456277-4
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  • 3
    Online Resource
    Online Resource
    Impact of methodological choices in comparative effectiveness studies: application in natalizumab versus fingolimod comparison among patients with multiple sclerosis
    Springer Science and Business Media LLC ; 2022
    In:  BMC Medical Research Methodology Vol. 22, No. 1 ( 2022-12)
    Details
    In: BMC Medical Research Methodology, Springer Science and Business Media LLC, Vol. 22, No. 1 ( 2022-12)
    Abstract: Natalizumab and fingolimod are used as high-efficacy treatments in relapsing–remitting multiple sclerosis. Several observational studies comparing these two drugs have shown variable results, using different methods to control treatment indication bias and manage censoring. The objective of this empirical study was to elucidate the impact of methods of causal inference on the results of comparative effectiveness studies. Methods Data from three observational multiple sclerosis registries (MSBase, the Danish MS Registry and French OFSEP registry) were combined. Four clinical outcomes were studied. Propensity scores were used to match or weigh the compared groups, allowing for estimating average treatment effect for treated or average treatment effect for the entire population. Analyses were conducted both in intention-to-treat and per-protocol frameworks. The impact of the positivity assumption was also assessed. Results Overall, 5,148 relapsing–remitting multiple sclerosis patients were included. In this well-powered sample, the 95% confidence intervals of the estimates overlapped widely. Propensity scores weighting and propensity scores matching procedures led to consistent results. Some differences were observed between average treatment effect for the entire population and average treatment effect for treated estimates. Intention-to-treat analyses were more conservative than per-protocol analyses. The most pronounced irregularities in outcomes and propensity scores were introduced by violation of the positivity assumption. Conclusions This applied study elucidates the influence of methodological decisions on the results of comparative effectiveness studies of treatments for multiple sclerosis. According to our results, there are no material differences between conclusions obtained with propensity scores matching or propensity scores weighting given that a study is sufficiently powered, models are correctly specified and positivity assumption is fulfilled.
    Type of Medium: Online Resource
    ISSN: 1471-2288
    URL: Article
    DOI: 10.1186/s12874-022-01623-8
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2022
    detail.hit.zdb_id: 2041362-2
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  • 4
    Online Resource
    Online Resource
    Introduction and transmission of SARS-CoV-2 lineage B.1.1.7, Alpha variant, in Denmark
    Springer Science and Business Media LLC ; 2022
    In:  Genome Medicine Vol. 14, No. 1 ( 2022-12)
    Details
    In: Genome Medicine, Springer Science and Business Media LLC, Vol. 14, No. 1 ( 2022-12)
    Abstract: In early 2021, the SARS-CoV-2 lineage B.1.1.7 (Alpha variant) became dominant across large parts of the world. In Denmark, comprehensive and real-time test, contact-tracing, and sequencing efforts were applied to sustain epidemic control. Here, we use these data to investigate the transmissibility, introduction, and onward transmission of B.1.1.7 in Denmark. Methods We analyzed a comprehensive set of 60,178 SARS-CoV-2 genomes generated from high-throughput sequencing by the Danish COVID-19 Genome Consortium, representing 34% of all positive cases in the period 14 November 2020 to 7 February 2021. We calculated the transmissibility of B.1.1.7 relative to other lineages using Poisson regression. Including all 1976 high-quality B.1.1.7 genomes collected in the study period, we constructed a time-scaled phylogeny, which was coupled with detailed travel history and register data to outline the introduction and onward transmission of B.1.1.7 in Denmark. Results In a period with unchanged restrictions, we estimated an increased B.1.1.7 transmissibility of 58% (95% CI: [56%, 60%]) relative to other lineages. Epidemiological and phylogenetic analyses revealed that 37% of B.1.1.7 cases were related to the initial introduction in November 2020. The relative number of cases directly linked to introductions varied between 10 and 50% throughout the study period. Conclusions Our findings corroborate early estimates of increased transmissibility of B.1.1.7. Both substantial early expansion when B.1.1.7 was still unmonitored and continuous foreign introductions contributed considerably to case numbers. Finally, our study highlights the benefit of balanced travel restrictions and self-isolation procedures coupled with comprehensive surveillance efforts, to sustain epidemic control in the face of emerging variants.
    Type of Medium: Online Resource
    ISSN: 1756-994X
    URL: Article
    DOI: 10.1186/s13073-022-01045-7
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2022
    detail.hit.zdb_id: 2484394-5
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  • 5
    Online Resource
    Online Resource
    The zebrafish reference genome sequence and its relationship to the human genome
    Springer Science and Business Media LLC ; 2013
    In:  Nature Vol. 496, No. 7446 ( 2013-04-25), p. 498-503
    Details
    In: Nature, Springer Science and Business Media LLC, Vol. 496, No. 7446 ( 2013-04-25), p. 498-503
    Type of Medium: Online Resource
    ISSN: 0028-0836 , 1476-4687
    URL: Article
    DOI: 10.1038/nature12111
    RVK:
    TA 1000
    RVK:
    UA 1000
    RVK:
    WA 15000
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2013
    detail.hit.zdb_id: 120714-3
    detail.hit.zdb_id: 1413423-8
    SSG: 11
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    Online Resource
  • 6
    Online Resource
    Online Resource
    Bioactive potential of endophytic fungi isolated from Phyllanthus niruri L.
    Bangladesh Academy of Sciences ; 2020
    In:  Bangladesh Journal of Scientific and Industrial Research Vol. 55, No. 4 ( 2020-12-27), p. 311-318
    Details
    In: Bangladesh Journal of Scientific and Industrial Research, Bangladesh Academy of Sciences, Vol. 55, No. 4 ( 2020-12-27), p. 311-318
    Abstract: Present work describes the isolation and morphological identification of endophytic fungi from Phyllanthus niruri L. including their chemical and bioactivity screening. Two isolated and purified endophytic fungi with the internal strain numbers PNRE and PNLE were taxonomically identified as Colletotrichum sp. and Fusarium sp., respectively. Preliminary chemical screening of the fungal extracts through thin layer chromatography (TLC) revealed the presence of various components. PNLE showed significant antifungal activity against the fungi Aspergillus niger (24 mm) and Aspergillus flavus (20 mm). Extracts of PNRE and PNLE gave significant cytotoxic activity with LC50 values of 1.08 μg mL-1 and 1.05 μg mL-1, respectively in the brine shrimp lethality bioassay. PNRE extract showed mild scavenging of DPPH with IC50 value of 96.06 μg mL-1 during antioxidant activity screening. Crystal formation was observed in the crude PNRE fungal extract which was purified using methanol/dichloromethane (0-20%) to obtain pure white crystal and the structure was elucidated by NMR (1H NMR and 13C NMR) spectroscopic analysis to be confirmed as ergosterol. Since isolated fungi showed promising antifungal and cytotoxic activities, the crude extract of endophytic fungi of P. niruri could be considered as a promising source for isolation of potential bioactive compounds. Bangladesh J. Sci. Ind. Res.55(4), 311-318, 2020
    Type of Medium: Online Resource
    ISSN: 2224-7157 , 0304-9809
    URL: Article
    DOI: 10.3329/bjsir.v55i4.50964
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2020
    detail.hit.zdb_id: 2381023-3
    SSG: 11
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    Online Resource
  • 7
    Online Resource
    Online Resource
    Thoracopagus conjoined twin - a case report
    Bangladesh Academy of Sciences ; 1970
    In:  Bangladesh Journal of Medical Science Vol. 10, No. 4 ( 1970-01-01), p. 289-292
    Details
    In: Bangladesh Journal of Medical Science, Bangladesh Academy of Sciences, Vol. 10, No. 4 ( 1970-01-01), p. 289-292
    Abstract: A patient at her 38+ wks of pregnancy as a ultrasonographically diagnosed case of conjoined twin admitted in our department with ruptured membrane. Two live female babies joined at the chest were delivered by caesarean section. The parents refused a separation operation and the mother and the babies were discharged from hospital at 6th post natal day. A review of the literature suggests that early diagnosis by a combination of ultrasound and MRI is essential for management as it provides prognosis for viability and process of surgical separation and also the opportunity for early counseling of parents and termination if indicated. Key world: Conjoined twins; thoracopagus; prenatal diagnosis; separation procedure DOI: http://dx.doi.org/10.3329/bjms.v10i4.9504 BJMS 2011; 10 (4): 289-292
    Type of Medium: Online Resource
    ISSN: 2076-0299 , 2223-4721
    URL: Article
    DOI: 10.3329/bjms.v10i4.9504
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 1970
    detail.hit.zdb_id: 2548724-3
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  • 8
    Online Resource
    Online Resource
    In silico analysis of Gracilaria changii proteins for potential bioactive peptides
    IOP Publishing ; 2022
    In:  IOP Conference Series: Earth and Environmental Science Vol. 967, No. 1 ( 2022-01-01), p. 012017-
    Details
    In: IOP Conference Series: Earth and Environmental Science, IOP Publishing, Vol. 967, No. 1 ( 2022-01-01), p. 012017-
    Abstract: Gracilaria changii is a red seaweed species in Malaysia with high protein content (12.57% (dry basis)). Thus, G. changii proteins are potential precursors for producing bioactive peptides. To date, no study has been reported on the potential of G. changii proteins as potential precursors for bioactive peptides. In this study, fourteen G. changii proteins were selected as potential precursors of bioactive peptides using in silico approach. It was found that the most potential bioactivity was dipeptidyl peptidase-IV (DPP IV) inhibitory and angiotensin-I converting enzyme (ACE) inhibitory activities. Papain, ficin and stem bromelain were used for in-silico proteolysis. Stem bromelain was found to be more effective in terms of the release of fragments with a given activity. Furthermore, two tripeptides (ACF and YCL) were screened as novel and promising bioactive peptides. The characteristics of both peptides were also analyzed using PeptideRanker, PepCalc, Peptide Cutter, ToxinPred, AllerTop and AHTpin bioinformatic tools. The bioinformatic tools predicted that both peptides were non-toxic, non-allergen and highly potential. The present work suggests that G. changii can serve as a potential source of bioactive peptides and these findings can provide a basis for future in-vitro and in-vivo study of bioactive peptides from G. changii proteins.
    Type of Medium: Online Resource
    ISSN: 1755-1307 , 1755-1315
    URL: Article
    DOI: 10.1088/1755-1315/967/1/012017
    Language: Unknown
    Publisher: IOP Publishing
    Publication Date: 2022
    detail.hit.zdb_id: 2434538-6
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  • 9
    Online Resource
    Online Resource
    Sentinel Lymph Node Mapping with Gamma Probe in Carcinoma of Breast: Initial Experience in Evercare Hospital Dhaka
    Bangladesh Academy of Sciences ; 2022
    In:  Bangladesh Journal of Nuclear Medicine Vol. 24, No. 1-2 ( 2022-05-24), p. 13-17
    Details
    In: Bangladesh Journal of Nuclear Medicine, Bangladesh Academy of Sciences, Vol. 24, No. 1-2 ( 2022-05-24), p. 13-17
    Abstract: Background: The sentinel lymph node (SLN) is the first draining node from a cancer-bearing area and therefore can manifest metastasis. In breast cancer SLN has been shown to predict the axillary nodal stage. Axillary dissection provides information determining prognosis and need for adjuvant therapy but often carries certain morbidities. Our aim was to determine the feasibility of detecting the SLN and whether the SLN accurately predicts the axillary status. Materials and Methods: Twelve patients having mean age of 40.5 ± 10.9 years, ranging from 28 to 56 years with stage I and II breast cancer and non-palpable axillary nodes from November 2016 to December 2018 were included in this study. The sentinel node was detected with Tc-99m-labelled nano colloid (radiotracer). Dual Head SPECT Gamma Camera and Gamma Probe was used in the same sitting for identification and surface marking of the SLN. Surgical resection of SLN was done followed by frozen section biopsy. Results: The tumor size ranged from 〈 2cm to ≤5cm), SLNs were identified in 11 out of 12 cases, one SLN in 9 patients and two SLNs in remaining two patients during SLN mapping. Conclusion: This was an initial experience in a single hospital, where SLN mapping and biopsy proved feasible and successful. By this method, patients who are negative on frozen section biopsy would be spared from axillary lymph node dissection. However, further practice is required to reach a firm conclusion and long term follow up is also essential. Bangladesh J. Nuclear Med. 24(1 & 2): 13-17, 2021
    Type of Medium: Online Resource
    ISSN: 1562-3831
    URL: Article
    DOI: 10.3329/bjnm.v24i1-2.59330
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2022
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  • 10
    Online Resource
    Online Resource
    Erratum: Corrigendum: The zebrafish reference genome sequence and its relationship to the human genome
    Springer Science and Business Media LLC ; 2014
    In:  Nature Vol. 505, No. 7482 ( 2014-1), p. 248-248
    Details
    In: Nature, Springer Science and Business Media LLC, Vol. 505, No. 7482 ( 2014-1), p. 248-248
    Type of Medium: Online Resource
    ISSN: 0028-0836 , 1476-4687
    URL: Article
    DOI: 10.1038/nature12813
    RVK:
    TA 1000
    RVK:
    UA 1000
    RVK:
    WA 15000
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2014
    detail.hit.zdb_id: 120714-3
    detail.hit.zdb_id: 1413423-8
    SSG: 11
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