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  • 1
    Online Resource
    Online Resource
    Novel Multifunctional Silver Nanocomposite Serves as a Resistance-Reversal Agent to Synergistically Combat Carbapenem-Resistant Acinetobacter baumannii
    American Chemical Society (ACS) ; 2021
    In:  ACS Applied Materials & Interfaces Vol. 13, No. 26 ( 2021-07-07), p. 30434-30457
    Details
    In: ACS Applied Materials & Interfaces, American Chemical Society (ACS), Vol. 13, No. 26 ( 2021-07-07), p. 30434-30457
    Type of Medium: Online Resource
    ISSN: 1944-8244 , 1944-8252
    URL: Article
    URL: Article
    DOI: 10.1021/acsami.1c10309
    DOI: 10.1021/acsami.1c10309.s001
    Language: English
    Publisher: American Chemical Society (ACS)
    Publication Date: 2021
    detail.hit.zdb_id: 2467494-1
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  • 2
    Online Resource
    Online Resource
    A Compartmental Silica Nanoreactor for Multienzyme‐Regulated Superactive Catalytic Therapy
    Wiley ; 2021
    In:  Advanced Functional Materials Vol. 31, No. 43 ( 2021-10)
    Details
    In: Advanced Functional Materials, Wiley, Vol. 31, No. 43 ( 2021-10)
    Abstract: Many tumor therapies take advantage of upsetting the redox balance in tumor cells, but to do so requires excessive biochemical or physical attacks. The high‐throughput simulation using multi‐pathway techniques described herein can yield an increased efficacy in bio‐oxidation. In this study, compartmental hierarchical nanoreactors are developed as an efficient multi‐pathway singlet oxygen ( 1 O 2 ) generation system for superactive biocatalytic tumor therapy. The penetrated super cavity and connected dual‐mesopore channels of the compartmental multienzyme nanoreactors are designed using the proposed heterogeneous template assembly for multi‐enzyme complex (superoxide dismutase (SOD)‐lactoperoxidase (LPO)) and photosensitizer molecule (indocyanine green (ICG)) encapsulation. Benefiting by the enhanced direct substrate diffusion between the interacting SOD–LPO complex and decrease in external diffusion, the parallel catalysis combined by the superactive cascade biocatalysis and enzyme‐promoted photosensitization effect is verified by this compartmental silica nanoreactor system. The parallel pathways not only make full use of the products of SOD (H 2 O 2 and O 2 ), but also exhibit outstanding capability for 1 O 2 production, at ≈2.15 and 1.70 times augmented 1 O 2 , respectively. Both in vitro and in vivo studies demonstrate the synergetic 1 O 2 ‐mediated inhibition of tumor proliferation, lending this strategy great potential for the treatment of hypoxic tumors.
    Type of Medium: Online Resource
    ISSN: 1616-301X , 1616-3028
    URL: Issue
    URL: Article
    DOI: 10.1002/adfm.v31.43
    DOI: 10.1002/adfm.202103531
    Language: English
    Publisher: Wiley
    Publication Date: 2021
    detail.hit.zdb_id: 2029061-5
    detail.hit.zdb_id: 2039420-2
    SSG: 11
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  • 3
    Online Resource
    Online Resource
    Tissue Fluid Triggered Enzyme Polymerization for Ultrafast Gelation and Cartilage Repair
    Wiley ; 2021
    In:  Angewandte Chemie Vol. 133, No. 36 ( 2021-09), p. 20135-20140
    Details
    In: Angewandte Chemie, Wiley, Vol. 133, No. 36 ( 2021-09), p. 20135-20140
    Abstract: The in situ gelation of injectable precursors is desirable in the field of tissue regeneration, especially in the context of irregular defect filling. The current driving forces for fast gelation include the phase‐transition of thermally sensitive copolymers, click chemical reactions with tissue components, and metal coordination effect. However, the rapid formation of tough hydrogels remains a challenge. Inspired by aerobic metabolism, we herein propose a tissue‐fluid‐triggered cascade enzymatic polymerization process catalyzed by glucose oxidase and ferrous glycinate for the ultrafast gelation of acryloylated chondroitin sulfates and acrylamides. The highly efficient production of carbon radicals and macromolecules contribute to rapid polymerization for soft tissue augmentation in bone defects. The copolymer hydrogel demonstrated the regeneration‐promoting capacity of cartilage. As the first example of using artificial enzyme complexes for in situ polymerization, this work offers a biomimetic approach to the design of strength‐adjustable hydrogels for bio‐implanting and bio‐printing applications.
    Type of Medium: Online Resource
    ISSN: 0044-8249 , 1521-3757
    URL: Issue
    URL: Article
    DOI: 10.1002/ange.v133.36
    DOI: 10.1002/ange.202107789
    RVK:
    VA 2100
    RVK:
    VN 5020
    Language: English
    Publisher: Wiley
    Publication Date: 2021
    detail.hit.zdb_id: 505868-5
    detail.hit.zdb_id: 506609-8
    detail.hit.zdb_id: 514305-6
    detail.hit.zdb_id: 505872-7
    detail.hit.zdb_id: 1479266-7
    detail.hit.zdb_id: 505867-3
    detail.hit.zdb_id: 506259-7
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  • 4
    Online Resource
    Online Resource
    In Situ Fabrication of Benzoquinone Crystal Layer on the Surface of Nest‐Structural Ionohydrogel for Flexible “All‐in‐One” Supercapattery
    Wiley ; 2023
    In:  Advanced Materials Vol. 35, No. 12 ( 2023-03)
    Details
    In: Advanced Materials, Wiley, Vol. 35, No. 12 ( 2023-03)
    Abstract: Flexible energy‐storage devices lay the foundation for a convenient, advanced, fossil fuel‐free society. However, the fabrication of flexible energy‐storage devices remains a tremendous challenge due to the intrinsic dissimilarities between electrode and electrolyte. In this study, a strategy is proposed for fabricating a flexible electrode and electrolyte entirely inside a matrix. First, a nest‐structural and redox‐active ionohydrogel with excellent stretchability (up to 3000%) and conductivity (167.9 mS cm −1 ) is designed using a hydrated ionic liquid (HIL) solvent and chemical foaming strategy. The nest‐structure ionohydrogel provides sufficient “highways” and “service area”, and the cation in HIL facilitates the reaction, transportation, and deposition of benzoquinone. Subsequently, in situ, a novel benzoquinone crystal–gel interface (CGI) is in situ fabricated on the surface of the ionohydrogel through electrochemical deposition of benzoquinone. Thus, an integrated CGI‐gel platform is successfully achieved with a middle body as an electrolyte and the surficial redox‐active CGI membrane for electrochemical energy conversion and storage. Based on the CGI‐gel platform, an extreme simple and effective “stick‐to‐use” strategy is proposed for constructing flexible energy‐storage devices and then a series of flexible supercapatteries are fabricated with high stretchability and capacitance (5222.1 mF cm −2 at 600% strain), low self‐discharge and interfacial resistance and a wearable, self‐power and intelligent display.
    Type of Medium: Online Resource
    ISSN: 0935-9648 , 1521-4095
    URL: Issue
    URL: Article
    DOI: 10.1002/adma.v35.12
    DOI: 10.1002/adma.202208443
    RVK:
    UA 1538
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 1474949-X
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  • 5
    Online Resource
    Online Resource
    Review on the Creep Resistance of High-Temperature Titanium Alloy
    Springer Science and Business Media LLC ; 2021
    In:  Transactions of the Indian Institute of Metals Vol. 74, No. 2 ( 2021-02), p. 215-222
    Details
    In: Transactions of the Indian Institute of Metals, Springer Science and Business Media LLC, Vol. 74, No. 2 ( 2021-02), p. 215-222
    Type of Medium: Online Resource
    ISSN: 0972-2815 , 0975-1645
    URL: Article
    DOI: 10.1007/s12666-020-02137-x
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2021
    detail.hit.zdb_id: 2535335-4
    SSG: 19,1
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  • 6
    Online Resource
    Online Resource
    A “Square Box”-Structured Triboelectric Nanogenerator for Road Transportation Monitoring
    MDPI AG ; 2022
    In:  Polymers Vol. 14, No. 13 ( 2022-06-30), p. 2695-
    Details
    In: Polymers, MDPI AG, Vol. 14, No. 13 ( 2022-06-30), p. 2695-
    Abstract: Nowadays, with the rapid development of e-commerce, the transportation of products has become more and more frequent. However, how to monitor the situation of products effectively and conveniently during road transportation is a long-standing problem. In order to meet this problem in practical applications, we fabricated a triboelectric nanogenerator sensor with a “square box” structure (S-TENG) for detecting the vibration suffered by vehicles. Specifically, with the spring installed in the S-TENG as a trigger, the two friction layers can contact and then separate to generate the real-time electrical signals when the S-TENG receives external excitation. The output voltage signals of the S-TENG under different vibration states were tested and the results demonstrated that the peak and zero positions of the open-circuit voltage–output curve are related to amplitude and frequency, respectively. In addition, the subsequent simulation results, obtained by ANSYS and COMSOL software, were highly consistent with the experimental results. Furthermore, we built a platform to simulate the scene of the car passing through speed bumps, and the difference in height and the number of speed bumps were significantly distinguished according to the output voltage signals. Therefore, the S-TENG has broad application prospects in road transportation.
    Type of Medium: Online Resource
    ISSN: 2073-4360
    URL: Article
    DOI: 10.3390/polym14132695
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2527146-5
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  • 7
    Online Resource
    Online Resource
    Expression and prognostic value of SULT1A2 in bladder cancer
    Spandidos Publications ; 2021
    In:  Experimental and Therapeutic Medicine Vol. 22, No. 1 ( 2021-05-19)
    Details
    In: Experimental and Therapeutic Medicine, Spandidos Publications, Vol. 22, No. 1 ( 2021-05-19)
    Type of Medium: Online Resource
    ISSN: 1792-0981 , 1792-1015
    URL: Journal
    URL: Article
    DOI: 10.3892/etm
    DOI: 10.3892/etm.2021.10211
    Language: Unknown
    Publisher: Spandidos Publications
    Publication Date: 2021
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  • 8
    Online Resource
    Online Resource
    Wafer Bonding of SiC-AlN at Room Temperature for All-SiC Capacitive Pressure Sensor
    MDPI AG ; 2019
    In:  Micromachines Vol. 10, No. 10 ( 2019-09-23), p. 635-
    Details
    In: Micromachines, MDPI AG, Vol. 10, No. 10 ( 2019-09-23), p. 635-
    Abstract: Wafer bonding of a silicon carbide (SiC) diaphragm to a patterned SiC substrate coated with aluminum nitride (AlN) film as an insulating layer is a promising choice to fabricate an all-SiC capacitive pressure sensor. To demonstrate the bonding feasibility, a crystalline AlN film with a root-mean-square (RMS) surface roughness less than ~0.70 nm was deposited on a SiC wafer by a pulsed direct current magnetron sputtering method. Room temperature wafer bonding of SiC-AlN by two surface activated bonding (SAB) methods (standard SAB and modified SAB with Si nano-layer sputtering deposition) was studied. Standard SAB failed in the bonding, while the modified SAB achieved the bonding with a bonding energy of ~1.6 J/m2. Both the microstructure and composition of the interface were investigated to understand the bonding mechanisms. Additionally, the surface analyses were employed to confirm the interface investigation. Clear oxidation of the AlN film was found, which is assumed to be the failure reason of direct bonding by standard SAB.
    Type of Medium: Online Resource
    ISSN: 2072-666X
    URL: Article
    DOI: 10.3390/mi10100635
    Language: English
    Publisher: MDPI AG
    Publication Date: 2019
    detail.hit.zdb_id: 2620864-7
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  • 9
    Online Resource
    Online Resource
    Clinical outcomes of modified simple limbal epithelial transplantation for limbal stem cell deficiency in Chinese population: a retrospective case series
    Springer Science and Business Media LLC ; 2021
    In:  Stem Cell Research & Therapy Vol. 12, No. 1 ( 2021-12)
    Details
    In: Stem Cell Research & Therapy, Springer Science and Business Media LLC, Vol. 12, No. 1 ( 2021-12)
    Abstract: To report the clinical outcomes of a novel surgical technique, namely simple limbal epithelial transplantation (SLET), for the treatment of limbal stem cell deficiency (LSCD). Methods Thirteen patients (13 eyes) with LSCD who underwent autologous (10 eyes) or allogeneic (3 eyes) modified SLET between 2018 and 2021 were enrolled in this study. Grades of symblepharon, corneal conjunctivalization, vascularization, opacification, and visual acuity (VA) were evaluated preoperatively and postoperatively. In 2 cases, in vivo confocal microscopy (IVCM) and impression cytology (IC) were performed to assess the proliferation and degeneration of limbal tissue. Results At a postoperative follow-up of 6.5±5.3 (range, 2–20) months, 10 (10/13, 76.92%) eyes maintained a successful outcome. The grades of symblepharon, corneal conjunctivalization, vascularization, and opacification were significantly improved after SLET ( P 〈 0.05). Two-line improvement in VA was found in 6 (6/10, 60%) eyes of the successful cases. Recurrence of LSCD occurred in 3 (3/13, 23.08%) eyes, and conjunctival cyst occurred in 1 patient. After SLET, the morphology and structure of corneal epithelial cells and epithelial transition around the limbal tissue fragments were detected by IVCM and IC. Conclusions Our findings suggest that the SLET is a safe and effective technique for the treatment of LSCD. The corneal stroma and hAM can provide protection and nutrition for the limbal stem cells (LSCs) without negatively influencing the clinical outcomes. IVCM and IC after SLET can evaluate the effectiveness of surgery and the transition of LSCs and corneal epithelial cells.
    Type of Medium: Online Resource
    ISSN: 1757-6512
    URL: Article
    DOI: 10.1186/s13287-021-02345-2
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2021
    detail.hit.zdb_id: 2548671-8
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  • 10
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    Online Resource
    Guidelines on the Diagnosis and Treatment of Lateral Meniscal Lesions: A Consensus Statement by the Chinese Society of Sports Medicine
    SAGE Publications ; 2022
    In:  Orthopaedic Journal of Sports Medicine Vol. 10, No. 12 ( 2022-12-01), p. 232596712211380-
    Details
    In: Orthopaedic Journal of Sports Medicine, SAGE Publications, Vol. 10, No. 12 ( 2022-12-01), p. 232596712211380-
    Abstract: The lateral meniscus is a unique structure of the knee joint, and its anatomy, function, pathological process, and treatment are distinct from those of the medial meniscus. To date, no consensus on the management of lateral meniscal lesions has been published, and clinical decision-making is challenging. To facilitate this, consensus and practice guidelines for lateral meniscal lesions were developed and endorsed by the Chinese Society of Sports Medicine. Study Design: Consensus statement. Methods: This project followed the Delphi approach to the consensus process, involving steering, rating, and peer review groups. A total of 61 experts in the fields of sports medicine and arthroscopic surgery were invited to participate in the compilation of a consensus statement on lateral meniscal lesions. (The discoid lateral meniscus was addressed by separate consensus.) To begin, the steering group drafted a set of questions and replies regarding lateral meniscal lesions. An online panel discussion was then held to provide initial agreement and comments on the statements, followed by a round of anonymous voting. Results and feedback were sent to the steering group for a second draft. A second round of voting was then held, and each statement was discussed during a combined meeting of the steering and rating groups. Finally, a consensus draft was evaluated by a review group. Results: Fifty-three questions and answers addressing lateral meniscal lesions were drafted, and 20 statements were excluded because of redundant information during the first round of voting. Ultimately, 33 statements were completed, 9 of which were unanimous. Conclusion: This expert consensus process focused on the anatomy, function, pathological processes, and treatment of lateral meniscal lesions. Accepted recommendations in these areas can assist doctors and therapists in standardizing the management of related pathology. The consensus statement indicates that certain types of lateral meniscal tears that were previously considered irreparable can be repaired. Preservation of the lateral meniscus should be the first-line treatment whenever possible, because the long-term clinical and radiological outcomes are worse after partial meniscectomy.
    Type of Medium: Online Resource
    ISSN: 2325-9671 , 2325-9671
    URL: Article
    DOI: 10.1177/23259671221138082
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2706251-X
    SSG: 31
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