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  • 1
    In: Clinical Infectious Diseases, Oxford University Press (OUP), Vol. 75, No. 1 ( 2022-08-24), p. e1054-e1062
    Abstract: To combat the coronavirus disease 2019 (COVID-19) pandemic, nonpharmaceutical interventions (NPIs) were implemented worldwide, which impacted a broad spectrum of acute respiratory infections (ARIs). Methods Etiologically diagnostic data from 142 559 cases with ARIs, who were tested for 8 viral pathogens (influenza virus [IFV], respiratory syncytial virus [RSV] , human parainfluenza virus [HPIV], human adenovirus [HAdV] , human metapneumovirus [HMPV], human coronavirus [HCoV] , human bocavirus [HBoV], and human rhinovirus [HRV] ) between 2012 and 2021, were analyzed to assess the changes in respiratory infections in China during the first COVID-19 pandemic year compared with pre-pandemic years. Results Test-positive rates of all respiratory viruses decreased during 2020, compared to the average levels during 2012–2019, with changes ranging from −17.2% for RSV to −87.6% for IFV. Sharp decreases mostly occurred between February and August when massive NPIs remained active, although HRV rebounded to the historical level during the summer. While IFV and HMPV were consistently suppressed year-round, RSV, HPIV, HCoV, HRV, and HBoV resurged and went beyond historical levels during September 2020–January 2021, after NPIs were largely relaxed and schools reopened. Resurgence was more prominent among children & lt;18 years and in northern China. These observations remain valid after accounting for seasonality and long-term trend of each virus. Conclusions Activities of respiratory viral infections were reduced substantially in the early phases of the COVID-19 pandemic, and massive NPIs were likely the main driver. Lifting of NPIs can lead to resurgence of viral infections, particularly in children.
    Type of Medium: Online Resource
    ISSN: 1058-4838 , 1537-6591
    RVK:
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2022
    detail.hit.zdb_id: 2002229-3
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  • 2
    In: Journal of Infection, Elsevier BV, Vol. 81, No. 1 ( 2020-07), p. e89-e92
    Type of Medium: Online Resource
    ISSN: 0163-4453
    RVK:
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2020
    detail.hit.zdb_id: 2012883-6
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  • 3
    In: Human Gene Therapy, Mary Ann Liebert Inc, Vol. 21, No. 11 ( 2010-11), p. 1545-1554
    Type of Medium: Online Resource
    ISSN: 1043-0342 , 1557-7422
    Language: English
    Publisher: Mary Ann Liebert Inc
    Publication Date: 2010
    detail.hit.zdb_id: 1498064-2
    SSG: 12
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  • 4
    Online Resource
    Online Resource
    Acta Physica Sinica, Chinese Physical Society and Institute of Physics, Chinese Academy of Sciences ; 2018
    In:  Acta Physica Sinica Vol. 67, No. 18 ( 2018), p. 184704-
    In: Acta Physica Sinica, Acta Physica Sinica, Chinese Physical Society and Institute of Physics, Chinese Academy of Sciences, Vol. 67, No. 18 ( 2018), p. 184704-
    Abstract: The thermocapillary migration characteristics of a self-wetting drop on the non-uniformly heated, horizontal, solid substrate are investigagted by numerical simulation. Based on the lubrication theory, an evolution equation for the height of the two-dimensional drop is established. The substrate underlying the drop is subjected to a temperature gradient which induces surface tension gradient-driven drop deformation and migration. The self-rewetting fluid has non-monotonic dependence of the surface tension on temperature with a well-defined minimum, and the position of the minimum corresponding to the temperature on the substrate is called the critical point. The effect of the relationship between the critical point and the drop position on drop dynamics is analyzed. With the temperature sensitivity coefficient of three interfaces under the same condition, the substrate is illustrated with constant wettability. The direction of drop migration will alter as the initial drop location moves to the left relative to the critical point position, resulting from the variation of the interplay among thermocapillary, gravity, and capillarity forces within the drop. But the drop always migrates toward the high interfacial tension region due to the thermocapillary force. In the presence of substrate wettability variations, the drop migrates toward the low temperature region no matter where the drop is placed relative to the critical point. This is due to the fact that the deterioration of substrate wettability on the right side of the drop prevents the drop from migrating toward the hot region. Under the critical point being on the left or within the drop, as the initial drop location moves to the left relative to the critical point position, the enhancement of the thermocapillary force toward the left leads to increased moving speed of the left contact line and increased spreading area. When the critical point is positioned on the outer right side of the drop, the speed of the left contact line sharply decreases at t=6103, caused by the suddenly deteriorating substrate wettability. Hence, it is effective to manipulate the self-wetting drop movement by regulating the relationship between the critical point and the initial drop location. To inhibit the migration of the drop toward the cold region, the drop should be placed on the right side of the critical point.
    Type of Medium: Online Resource
    ISSN: 1000-3290 , 1000-3290
    Language: Unknown
    Publisher: Acta Physica Sinica, Chinese Physical Society and Institute of Physics, Chinese Academy of Sciences
    Publication Date: 2018
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  • 5
    Online Resource
    Online Resource
    Acta Physica Sinica, Chinese Physical Society and Institute of Physics, Chinese Academy of Sciences ; 2018
    In:  Acta Physica Sinica Vol. 67, No. 11 ( 2018), p. 114702-
    In: Acta Physica Sinica, Acta Physica Sinica, Chinese Physical Society and Institute of Physics, Chinese Academy of Sciences, Vol. 67, No. 11 ( 2018), p. 114702-
    Abstract: The dynamics of evaporating sessile drop on a uniformly heated, horizontal, solid substrate is considered. On the basis of lubrication theory and Navier slip condition, an evolution equation for the height of the two-dimensional drop is established. The numerical results show that the drop evolution is governed by capillary force, gravity, thermal capillary force and evaporation. Gravity exerts a promoting effect on drop spreading, while capillary force and thermal capillary force inhibit drop spreading. The typical dynamic features including contact line pinning or partial pinning modes during the drop evaporation are illustrated by changing the temperature-sensitive coefficient in the present model, and the drop lifetime of contact pinning mode is found to be shorter than that of contact line partial pinning mode. Under the same temperature-sensitive coefficient of three interfaces, the drop evolution is indicated with three typical stages: 1) spreading stage, 2) contact line pinning stage, and 3) both contact line and contact angle decreasing stage. As interface tension of liquid-gas or liquid-solid is more sensitive to temperature, the drop evolution is divided into two typical stages: 1) spreading stage and 2) contact line pinning stage. The equilibrium contact angle tends to be smaller and the substrate wettability is improved, leading to the increased spreading speed, the prolonged time of the contact line to reach pinning: the faster the evaporation rate, the shorter the lifetime of drop is. Additionally, the same effect of sensitivity of liquid-gas and liquid-solid interface tension to temperature on the wettability of substrate is observed. When the interface tension of solid-gas is more sensitive to temperature, the drop evolution is characterized in four typical stages: 1) spreading stage, 2) contact line pinning stage, 3) contact line de-pinning and constant contact angle stage, and 4) both contact line and contact angle decreasing stage. The equilibrium contact angle tends to be greater and the substrate wettability is deteriorated, leading the spreading speed to decrease. Hence, it is more effective to manipulate the drop movement in the presence of evaporation by regulating the temperature-sensitive coefficient of the solid-gas interface.
    Type of Medium: Online Resource
    ISSN: 1000-3290 , 1000-3290
    Language: Unknown
    Publisher: Acta Physica Sinica, Chinese Physical Society and Institute of Physics, Chinese Academy of Sciences
    Publication Date: 2018
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  • 6
    In: Infectious Diseases of Poverty, Springer Science and Business Media LLC, Vol. 12, No. 1 ( 2023-07-04)
    Abstract: Acute diarrhea with fever can potentially represent a more severe form of the disease compared to non-febrile diarrhea. This study was to investigate the epidemiological characteristics and enteric pathogen composition of febrile-diarrheal patients, and to explore factors including pathogens associated with fever by age group. Methods A nationwide surveillance study of acute diarrheal patients of all ages was conducted in 217 sentinel hospitals from 31 provinces (autonomous regions or municipalities) in China between 2011 and 2020. Seventeen diarrhea-related pathogens, including seven viruses and ten bacteria, were investigated and their association with occurrence of fever symptoms was assessed using multivariate logistic analysis. Results A total of 146,296 patients with acute diarrhea (18.6% with fever) were tested. Th diarrheal children below 5 years had the highest frequency of fever (24.2%), and related to significantly higher prevalence of viral enteropathogens (40.2%) as compared with other age groups ( P   〈  0.001). Within each age group, the febrile-diarrheal patients were associated with a significantly higher prevalence of bacterial pathogens than afebrile-diarrheal patients (all P   〈  0.01). There was discrepancy when each pathogen was compared, i.e., nontyphoidal Salmonella (NTS) was overrepresented in febrile vs non-febrile patients of all age groups, while the febrile vs non-febrile difference for diarrheagenic Escherichia coli (DEC) was only significant for adult groups. The multivariate analysis revealed significant association between fever and infection with rotavirus A among children [odds ratio ( OR ) = 1.60], for DEC in adult groups ( OR  = 1.64), for NTS in both children ( OR  = 2.95) and adults ( OR  = 3.59). Conclusions There are significant discrepancy of the infected enteric pathogens in patients with acute diarrhea with fever between age groups, and it is valuable for priority detection of NTS and rotavirus A in patients with children  〈  5 years old and NTS and DEC in adult patients. The results may be useful in identifying dominant pathogen candidates for the application of diagnostic assays and prevention control. Graphical Abstract
    Type of Medium: Online Resource
    ISSN: 2049-9957
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
    detail.hit.zdb_id: 2689396-4
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  • 7
    Online Resource
    Online Resource
    S. Karger AG ; 2013
    In:  Medical Principles and Practice Vol. 22, No. 2 ( 2013), p. 200-203
    In: Medical Principles and Practice, S. Karger AG, Vol. 22, No. 2 ( 2013), p. 200-203
    Abstract: 〈 b 〉 〈 i 〉 Objective: 〈 /i 〉 〈 /b 〉 To report a hypertensive and systematically pigmented female with primitive neuroectodermal tumors. 〈 b 〉 〈 i 〉 Clinical Presentation and Intervention: 〈 /i 〉 〈 /b 〉 A female patient presented with a complaint of right flank pain. She had a right renal space-occupying lesion, underwent right radical nephrectomy, and returned to normotensive postoperatively. The pathological examination identified typical primitive neuroectodermal tumor histology. During a 60-month follow-up period, she remained normotensive and demonstrated normal renal and adrenal functions. 〈 b 〉 〈 i 〉 Conclusion: 〈 /i 〉 〈 /b 〉 Early diagnosis and definitive surgery led to the patient’s long-term survival.
    Type of Medium: Online Resource
    ISSN: 1011-7571 , 1423-0151
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2013
    detail.hit.zdb_id: 1482963-0
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  • 8
    Online Resource
    Online Resource
    Acta Physica Sinica, Chinese Physical Society and Institute of Physics, Chinese Academy of Sciences ; 2018
    In:  Acta Physica Sinica Vol. 67, No. 21 ( 2018), p. 214703-
    In: Acta Physica Sinica, Acta Physica Sinica, Chinese Physical Society and Institute of Physics, Chinese Academy of Sciences, Vol. 67, No. 21 ( 2018), p. 214703-
    Abstract: The aim of the present paper is to investigate the gravity-driven draining process containing soluble surfactant when considering the coupling effects of surface elasticity and surfactant solubility. A nonlinear coupling evolution equation including liquid film thickness, surface velocity and surfactant concentration (both on the surface and in the bulk) is established based on the lubrication theory. Assuming that the top of liquid film is attached to the wireframe and the bottom is connected to a reservoir, the drainage evolution is simulated with the software called FreeFem. The effects of surface elasticity and solubility on liquid film draining are discussed under their coupling. The simulation results show that the surface elasticity is an indispensable factor in the process of liquid film drainage with soluble surfactant, and the surfactant solubility also has an important influence on the process. At the initial stage of liquid draining, the initial thickness of liquid film increases with increasing surface elasticity, and the surface tends to be more rigid; with the drainage proceeding, the liquid film with high and low elasticity illustrate different notable draining features:in the case of low surface elasticity, the distribution of surfactant forms a surface tension gradient from top to bottom on the film surface, leading to positive Marangoni effect that counteracts gravity. However, in the case of high elasticity, the film surface presents a surface tension gradient from bottom to top, resulting in a reverse Marangoni effect, which accelerates the draining and makes the film more susceptible to instability. The solubility of surfactant dominates the number of adsorbent molecules on the film surface, which affects the surface elasticity. When the solubility of the surfactant is great (β → 0), the film is extremely unstable, and it breaks down quickly. As the solubility decreases (namely, β increases), the stability of the film increases, and the initial surface elasticity also rises. The surface elasticity gradually approaches to the limiting dilational elasticity modulus due to the film being thinner.
    Type of Medium: Online Resource
    ISSN: 1000-3290 , 1000-3290
    Language: Unknown
    Publisher: Acta Physica Sinica, Chinese Physical Society and Institute of Physics, Chinese Academy of Sciences
    Publication Date: 2018
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  • 9
    Online Resource
    Online Resource
    University of Chicago Press ; 2022
    In:  The Journal of Geology Vol. 130, No. 4 ( 2022-07-01), p. 297-310
    In: The Journal of Geology, University of Chicago Press, Vol. 130, No. 4 ( 2022-07-01), p. 297-310
    Type of Medium: Online Resource
    ISSN: 0022-1376 , 1537-5269
    RVK:
    Language: English
    Publisher: University of Chicago Press
    Publication Date: 2022
    detail.hit.zdb_id: 3041-7
    detail.hit.zdb_id: 1473840-5
    SSG: 13
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  • 10
    Online Resource
    Online Resource
    Hindawi Limited ; 2022
    In:  Journal of Sensors Vol. 2022 ( 2022-2-3), p. 1-17
    In: Journal of Sensors, Hindawi Limited, Vol. 2022 ( 2022-2-3), p. 1-17
    Abstract: Tracking ground moving target with sensors proves to be a challenge due to the uncertainty of target motion area, the existence of Doppler blind zone (DBZ), and the complex terrain. In this paper, a multisensor management method based on DBZ information is presented, in which the available sensors are selected to obtain the best operational revenues for ground moving target tracking. First, the ground target motion model is established considering the off-road/on-road state based on road topology information. Second, the sensor measurement model is given combined with the DBZ information, and a decorrelation method of measurement noise is proposed. Third, a target state estimation algorithm is derived using particle filter, in which the DBZ information is regarded as prior information. Then, combined with the variable structure interacting multiple model method, an estimation algorithm for tracking maneuvering target is proposed. Furthermore, an optimization model of nonmyopic sensor management is constructed to obtain the best sensor management scheme. Finally, the advancement and effectiveness of the proposed management method are verified in the simulations.
    Type of Medium: Online Resource
    ISSN: 1687-7268 , 1687-725X
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2022
    detail.hit.zdb_id: 2397931-8
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