In:
Hepatology Research, Wiley, Vol. 50, No. 8 ( 2020-08), p. 996-999
Abstract:
The albumin, bilirubin, and platelet (ABP) criteria was proposed to avoid screening endoscopy for detecting high‐risk varices (HRV) and it has high diagnostic accuracy. We carried out a retrospective cross‐sectional study to verify the diagnostic accuracy. Methods A total of 610 patients with advanced fibrosis were enrolled in the study. ABP criteria are defined as follows: albumin 〉 4.0 g/dL, bilirubin 〈 22 μmol/L, and platelets 〉 114 000/μL. Results Background liver disease were hepatitis C/hepatitis B/non‐alcoholic fatty liver disease/others:405 (66.4%)/67 (10.5%)/78 (12.8%)/60 (10.3%). A total of 105 patients (17.2%) had HRV. In multivariate analysis, serum bilirubin 〈 22 μmol/L (HR 2.00, 95% CI 1.2–3.4), albumin 〉 4.0 g/dL (HR 2.56, 95% CI 1.7–3.8), and platelets 〉 114 000/μL (HR 3.52, 95% CI 2.1–5.8) levels were independently associated with no presence of HRV. When the ABP criteria were examined, 200 patients (32.8%) fulfilled the criteria, and 194 patients had no HRV (positive predictive value 97.0%) When classified by etiologies (hepatitis C/hepatitis B/non‐alcoholic fatty liver disease), positive predictive value were 97.7/100/92.0%, respectively. Conclusions The ABP criteria are easy to examine, because they use only standard laboratory tests, and they are available for screening patients who might avoid endoscopy regardless of etiologies.
Type of Medium:
Online Resource
ISSN:
1386-6346
,
1872-034X
Language:
English
Publisher:
Wiley
Publication Date:
2020
detail.hit.zdb_id:
2006439-1
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