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  • 1
    Online Resource
    Online Resource
    Reinforced Active Middle Ear Implant Fixation in Incus Vibroplasty
    Ovid Technologies (Wolters Kluwer Health) ; 2015
    In:  Ear & Hearing Vol. 36, No. 1 ( 2015-01), p. 72-81
    Details
    In: Ear & Hearing, Ovid Technologies (Wolters Kluwer Health), Vol. 36, No. 1 ( 2015-01), p. 72-81
    Type of Medium: Online Resource
    ISSN: 0196-0202
    URL: Article
    DOI: 10.1097/AUD.0000000000000078
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2015
    detail.hit.zdb_id: 2081799-X
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  • 2
    Online Resource
    Online Resource
    Long-term Results and Revision Surgery of the Vibrant Soundbridge : Presenting Author: Robert Mlynski
    Cambridge University Press (CUP) ; 2016
    In:  The Journal of Laryngology & Otology Vol. 130, No. S3 ( 2016-05), p. S96-S96
    Details
    In: The Journal of Laryngology & Otology, Cambridge University Press (CUP), Vol. 130, No. S3 ( 2016-05), p. S96-S96
    Type of Medium: Online Resource
    ISSN: 0022-2151 , 1748-5460
    URL: Article
    DOI: 10.1017/S0022215116003716
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2016
    detail.hit.zdb_id: 2013209-8
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  • 3
    Online Resource
    Online Resource
    Inductive Charging for Electric Vehicles—A Techno-economic Assessment
    Springer Science and Business Media LLC ; 2011
    In:  Zeitschrift für Energiewirtschaft Vol. 35, No. 3 ( 2011-9), p. 209-219
    Details
    In: Zeitschrift für Energiewirtschaft, Springer Science and Business Media LLC, Vol. 35, No. 3 ( 2011-9), p. 209-219
    Type of Medium: Online Resource
    ISSN: 0343-5377 , 1866-2765
    URL: Article
    DOI: 10.1007/s12398-010-0040-y
    RVK:
    ZG 1100
    RVK:
    QA 10000
    Language: German
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2011
    detail.hit.zdb_id: 132891-8
    detail.hit.zdb_id: 2452486-4
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  • 4
    Online Resource
    Online Resource
    Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation
    MyJove Corporation ; 2020
    In:  Journal of Visualized Experiments , No. 156 ( 2020-02-29)
    Details
    In: Journal of Visualized Experiments, MyJove Corporation, , No. 156 ( 2020-02-29)
    Type of Medium: Online Resource
    ISSN: 1940-087X
    URL: Article
    DOI: 10.3791/60795-v
    Language: English
    Publisher: MyJove Corporation
    Publication Date: 2020
    detail.hit.zdb_id: 2259946-0
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  • 5
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    Comparison of total and partial ossicular replacement prostheses in patients with an intact stapes suprastructure
    Wiley ; 2020
    In:  The Laryngoscope Vol. 130, No. 3 ( 2020-03), p. 768-775
    Details
    In: The Laryngoscope, Wiley, Vol. 130, No. 3 ( 2020-03), p. 768-775
    Abstract: To compare the results of ossiculoplasty with two different partial ossicular replacement prostheses (PORP) to ossiculoplasty with a total ossicular replacement prosthesis (TORP) in patients with an intact stapes suprastructure. Methods All patients required primary or revision surgery for chronic middle ear disease and ossicular reconstruction with either a PORP or a TORP, as well as a with an intact stapes suprastructure. In total, 141 patients receiving classic tympanoplasty with PORP (N = 92), ossiculoplasty with PORP with ball joint (N = 22), or TORP (N = 27) between January 2011 and March 2017 were included in this study. The inclusion criterion was an intact stapes suprastructure. The underlying indication for surgery was either middle ear disease, such as cholesteatoma, or revision surgery for audiological improvement. The main outcome measures were four‐frequency pure tone average (0.5, 1, 2, 3 kHz) at early and late follow‐up after ossiculoplasty, the effects of clinical factors including the underlying middle ear disease, and primary or revision surgery. Results All patients showed a significantly reduced air‐bone gap (ABG 0.5, 1, 2, 3 kHz) at late follow‐up (mean: 18 dB) compared to preoperative measurements (mean: 25.5 dB). A significantly better outcome in ABG closure was shown among patients with a preoperatively intact tympanic membrane, with an intact stapes suprastructure or without preexisting cholesteatoma. Outcome was not significantly influenced by the prosthesis‐type, the creation of an open mastoid cavity, the status of the mucosa, or the indication for surgery. Conclusion TORP with an intact stapes suprastructure is a safe procedure and provides audiological outcomes similar to PORP. Level of Evidence 2C Laryngoscope , 130:768–775, 2020
    Type of Medium: Online Resource
    ISSN: 0023-852X , 1531-4995
    URL: Issue
    URL: Article
    DOI: 10.1002/lary.v130.3
    DOI: 10.1002/lary.28060
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2026089-1
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  • 6
    Online Resource
    Online Resource
    Open Mastoid Cavity Obliteration With a High-Porosity Hydroxyapatite Ceramic Leads to High Rate of Revision Surgery and Insufficient Cavity Obliteration
    Ovid Technologies (Wolters Kluwer Health) ; 2020
    In:  Otology & Neurotology Vol. 41, No. 1 ( 2020-01), p. e55-e63
    Details
    In: Otology & Neurotology, Ovid Technologies (Wolters Kluwer Health), Vol. 41, No. 1 ( 2020-01), p. e55-e63
    Abstract: To assess long-term results and present experience with a high-porosity hydroxyapatite ceramic for obliterating large open mastoid cavities. Study-Design: Cross-sectional cohort study. Setting: Tertiary academic referral center. Patients: All patients who underwent tympanomastoid surgery for chronic middle ear disease or revision surgery with reduction of an open mastoid cavity using a highly porous hydroxyapatite matrix material (HMM) between May 2005 and June 2013 were assessed for eligibility. Twenty three patients (56.9 ± 18.3 yr) were included. Intervention: Primary middle ear surgery or revision surgery using a HMM. Main Outcome Measures: Pure-tone average, computed tomography (CT), and magnetic resonance imaging (MRI) to investigate osseoinduction, osseointegration and presence of cholesteatoma, current quality of life assessed by Zurich Chronic Middle Ear Inventory and change in quality of life post-intervention assessed by the Glasgow Benefit Inventory. Results: Patients were reexamined after a mean follow-up period of 88.3 months (SD 21.4 mo) after obliteration of the open mastoid cavity with HMM. Compared with visit 1, patients showed a significantly reduced ABG at visit 2 (29.22 dB ± 2.71 dB versus 12.77 dB ± 3.46 dB). CT scan was carried out in 21 patients (91%) patients and 17 patients (74%) underwent MRI. Revision surgery was required in a total of 17 cases (74%). In four patients recurrent cholesteatoma was found at follow up. Conclusions: Poor cavity obliteration, a high rate of revision surgery and difficult differentiation between recurrent cholesteatoma and granulation tissue in CT scan was observed.
    Type of Medium: Online Resource
    ISSN: 1531-7129 , 1537-4505
    URL: Article
    DOI: 10.1097/MAO.0000000000002413
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2020
    detail.hit.zdb_id: 2058738-7
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  • 7
    Online Resource
    Online Resource
    Alternative Fixation of an Active Middle Ear Implant at the Short Incus Process
    S. Karger AG ; 2014
    In:  Audiology and Neurotology Vol. 19, No. 1 ( 2014), p. 1-11
    Details
    In: Audiology and Neurotology, S. Karger AG, Vol. 19, No. 1 ( 2014), p. 1-11
    Abstract: 〈 b 〉 〈 i 〉 Introduction: 〈 /i 〉 〈 /b 〉 Since 1996, the preferred approach for positioning the active middle-ear implant Vibrant Soundbridge© is a mastoidectomy and a posterior tympanotomy. With this device, placement of the floating mass transducer (FMT) on the long incus process is the standard method for treatment of mild-to-severe sensorineural hearing loss in the case of normal middle-ear anatomy. The aim of this study was to determine the vibrational effectiveness of FMT placement at the short incus process. 〈 b 〉 〈 i 〉 Materials and Methods: 〈 /i 〉 〈 /b 〉 An extended antrotomy and a posterior tympanotomy were performed in 5 fresh human temporal bones. As a control for normal middle-ear function, the tympanic membrane was stimulated acoustically and the vibration of the stapes footplate and the round-window (RW) membrane were (sequentially) measured by laser Doppler vibrometry. Vibration responses for coupling of an FMT to the long incus process (standard coupling) were compared to those for coupling to the short incus process. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 Apart from narrow frequency bands near 3 and 9 kHz for the stapes footplate and RW membrane, respectively, the velocity responses presented no significant differences between standard coupling of the FMT and coupling to the short incus process. 〈 b 〉 〈 i 〉 Conclusion: 〈 /i 〉 〈 /b 〉 Coupling the FMT to the short incus process may be a viable alternative in cases where the surgical approach is limited to an extended antrotomy. A reliable technique for attachment to the short incus process has yet to be developed.
    Type of Medium: Online Resource
    ISSN: 1420-3030 , 1421-9700
    URL: Article
    DOI: 10.1159/000354981
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2014
    detail.hit.zdb_id: 1481979-X
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  • 8
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    Online Resource
    Conditions for Highly Efficient and Reproducible Round-Window Stimulation in Humans
    S. Karger AG ; 2012
    In:  Audiology and Neurotology Vol. 17, No. 2 ( 2012), p. 133-138
    Details
    In: Audiology and Neurotology, S. Karger AG, Vol. 17, No. 2 ( 2012), p. 133-138
    Abstract: Round-window stimulation is a new clinical approach for the application of active middle-ear implants. To investigate factors influencing the efficiency of round-window stimulation, experiments in 6 human temporal bones were performed with different actuator geometries and coupling conditions. The experiments show that the amplitude ratio between stapes and round-window actuator vibration is most efficient when using a 1.0-mm diameter rod with a 30° inclined tip geometry and an attached silicone pad. In this case, the amplitude ratio is 0.34 for frequencies up to 1.5 kHz and 0.27 for frequencies up to 20 kHz, with a standard deviation of only 4–6 dB at most frequencies. The analysis of data presented here and in a companion paper suggests that control of proper round-window membrane pretension as well as the inclined tip geometry are the major requirements for maximal performance.
    Type of Medium: Online Resource
    ISSN: 1420-3030 , 1421-9700
    URL: Article
    DOI: 10.1159/000333807
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2012
    detail.hit.zdb_id: 1481979-X
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  • 9
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    Online Resource
    Patterned semiconductor structures modulate neuronal outgrowth: Implication for the development of a neurobionic interface
    Wiley ; 2018
    In:  Journal of Biomedical Materials Research Part A Vol. 106, No. 1 ( 2018-01), p. 65-72
    Details
    In: Journal of Biomedical Materials Research Part A, Wiley, Vol. 106, No. 1 ( 2018-01), p. 65-72
    Abstract: Auditory implants stimulate the neurons by broad electrical fields, which leads to a low number of spectral channels. A reduction in the distance between the electrode and the neuronal structures might lead to better electrical transduction. The use of microstructured semiconductors offers a large number of contacts, which could attract neurons and stimulate them individually. To investigate the interaction between neurons and semiconductors, differentiated neuronal precursor cells were cultured on silicon wafers. Different structures were added on the wafers by electron beam lithography, and deep reactive ion etching in different depths (2 and 7 µm). Grooved surfaces guided the neurons and resulted in straight oriented axons, but neuronal outgrowth was impaired by the 7 µm grooves. Within the 7 µm structures, the neuronal cell body was totally encased and the nuclei were deformed from a round to an elliptical shape. On both square and cylindrical structures neuronal bridging could be detected in different forms, either between the tops of the structures or between the bottom and the top. Furthermore, neuronal bridges were established on the lateral part of the structures, and change in direction of neuronal growth was induced by the structure. Finally, it could be shown that neuronal growth cones were particularly attracted by the top of the cylinders, which might allow for the stimulation of neurons via this structure. In conclusion, study results indicate that structured semiconductors can modulate neuronal growth and its direction, offering a novel method for the development of new implants with improved neuronal stimulation. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 106A: 65–72, 2018.
    Type of Medium: Online Resource
    ISSN: 1549-3296 , 1552-4965
    URL: Issue
    URL: Article
    DOI: 10.1002/jbm.a.v106.1
    DOI: 10.1002/jbm.a.36203
    Language: English
    Publisher: Wiley
    Publication Date: 2018
    detail.hit.zdb_id: 1477192-5
    SSG: 12
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  • 10
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    Online Resource
    Frictional Behavior of Cochlear Electrode Array Is Dictated by Insertion Speed and Impacts Insertion Force
    MDPI AG ; 2021
    In:  Applied Sciences Vol. 11, No. 11 ( 2021-06-02), p. 5162-
    Details
    In: Applied Sciences, MDPI AG, Vol. 11, No. 11 ( 2021-06-02), p. 5162-
    Abstract: Background: During cochlear implantation, the electrode array has significant friction with the sensitive endocochlear lining and causes mutual mechanical trauma while the array is being inserted. Both, the impact of insertion speed on electrode friction and the relationship of electrode insertion force and friction have not been adequately investigated to date. Methods: In this study, friction coefficients between a CI electrode array (31.5 mm) and a tissue simulating the endocochlear lining have been acquired, depending on different insertion speeds (0.1, 0.5, 1.0, 1.5, and 2.0 mm/s). Additionally, the electrode insertion forces during the placing into a scala tympani model were recorded and correlated with the friction coefficient. Results: It was shown that the friction coefficient reached the lowest value at an insertion speed of 0.1 mm/s (0.24 ± 0.13), a maximum occurred at 1.5 mm/s (0.59 ± 0.12), and dropped again at 2 mm/s (0.45 ± 0.11). Similar patterns were observed for the insertion forces. Consequently, a high correlation coefficient (0.9) was obtained between the insertion forces and friction coefficients. Conclusion: The present study reveals a non-linear increase in electrode array friction, when insertion speed raises and reports a high correlation between friction coefficient and electrode insertion force. This dependence is a relevant future parameter to evaluate and reduce cochlear implant insertion trauma. Significance statement: Here, we demonstrated a dependence between cochlear electrode insertion speed and its friction behavior and a high correlation to insertion force. Our study provides valuable information for the evaluation and prevention of cochlear implant insertion trauma and supports the optimization of cochlear electrode arrays regarding friction characteristics.
    Type of Medium: Online Resource
    ISSN: 2076-3417
    URL: Article
    DOI: 10.3390/app11115162
    Language: English
    Publisher: MDPI AG
    Publication Date: 2021
    detail.hit.zdb_id: 2704225-X
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