In:
Cancer Cytopathology, Wiley, Vol. 122, No. 12 ( 2014-12), p. 873-882
Abstract:
RAS mutations are found in approximately 20% to 45% of thyroid neoplasms and are associated with carcinoma in 74% to 87% of cases (most commonly follicular variant papillary thyroid carcinoma). In the current study, the authors report that subclassification of RAS mutations provides better insight into lesional characteristics. In particular, KRAS12/13 ‐mutated thyroid nodules are associated with a lower carcinoma outcome (41.7%) and frequent oncocytic changes.
Type of Medium:
Online Resource
ISSN:
1934-662X
,
1934-6638
DOI:
10.1002/cncy.v122.12
Language:
English
Publisher:
Wiley
Publication Date:
2014
detail.hit.zdb_id:
2599218-1
detail.hit.zdb_id:
2594979-2
detail.hit.zdb_id:
1429-1
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