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  • 1
    In: Journal of Animal Science, Oxford University Press (OUP), Vol. 97, No. 1 ( 2019-01-01), p. 269-278
    Type of Medium: Online Resource
    ISSN: 0021-8812 , 1525-3163
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2019
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  • 2
    In: Journal of Animal Science, Oxford University Press (OUP), Vol. 97, No. Supplement_2 ( 2019-07-29), p. 84-84
    Abstract: Thirty-two barrows were used in a 35-d experiment with the objective of evaluating effects of supplemental soluble fiber (dextrin) pre- and post-weaning on growth performance and VFA production. Pigs were blocked by genetics and BW, and randomly allotted to treatments in a 2x2 factorial design with or without fiber pre-weaning and with or without fiber post-weaning. Fiber was suspended in chocolate milk and administered orally through a syringe from 14 d prior to weaning until 4 d post-weaning, after which it was included in the diet at 1%. At weaning, pigs were group housed by treatment and allowed ad libitum access to a common starter diet. On d 4 post-weaning, pigs were moved to individual pens and fed diets with or without 1% fiber. Weights and feed intake were recorded 14 and 3 d prior to weaning and on d 0, 4, 11, and 21 post-weaning. On d 21 post-weaning, pigs were euthanized, and large intestine contents were collected for VFA analysis. Data were analyzed using the GLM procedure of SAS with pig as the experimental unit. Growth performance was not affected (P 〉 0.10) by treatment. A trend for an interaction of pre- and post-weaning fiber supplementation was observed for acetate (P = 0.052) and butyrate (P = 0.087) concentrations in large intestine contents. Pigs fed fiber only in the nursery had the highest acetate concentration, while pigs never receiving fiber had the lowest concentration. Pre-weaning fiber supplementation followed by no fiber in the nursery resulted in the highest butyrate concentrations with all other treatments being similar. Fiber supplementation pre-weaning tended (P = 0.053) to reduce isobutyrate concentrations. Pigs not receiving fiber post-weaning had increased valerate concentrations (P = 0.0245). There were no changes observed in propionate or isovalerate concentrations (P 〉 0.10). Fiber supplementation caused alterations in VFA concentrations when fed during pre- and post-weaning, indicating possible shifts in the microbiome, immune status and barrier function of the intestinal tract.
    Type of Medium: Online Resource
    ISSN: 0021-8812 , 1525-3163
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2019
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    SSG: 12
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  • 3
    Online Resource
    Online Resource
    Oxford University Press (OUP) ; 2018
    In:  Translational Animal Science Vol. 2, No. 4 ( 2018-10-01), p. 358-364
    In: Translational Animal Science, Oxford University Press (OUP), Vol. 2, No. 4 ( 2018-10-01), p. 358-364
    Abstract: Three thousand one hundred and eighty-two terminal cross pigs (barrows and gilts) PIC line 359 sires × 1,050 dams were used from three consecutive grow-finish groups (initial BW of 21.51 ± 0.42 kg, 31.61 ± 1.18 kg, 29.41 ± 0.28 kg for replicates 1–3). Pigs were randomly assigned to each pen at the start of the trial and the research period continued for 106, 94, and 100 d for the first, second, and third replicates, respectively. The experimental treatments were designed as a two by three factorial (pen space of 0.65 or 0.78 m2/pig with 10, 13, or 16 pigs per feeder space), each pen had an equal number of barrows and gilts with 20, 26, and 32 pigs per pen for the 10, 13, and 16 pigs per feeder space pens. Each pen was equipped with one double-sided wet/dry feeder, 37.5 cm wide, with one nipple drinker. All pigs had ad libitum access to feed and water supply during the trial period. Pigs for all the three replicates were fed with the same series of diets. Pigs were weighed by pen at the start of trial and at the end of the trial to calculate ADG. Feed was removed from the feeders and weighed to determine ADFI and G:F. To express floor space allowance, the k value was estimated by the equation: space per pig (m2)=k×BW (kg)0.67. No interactions (P & gt; 0.05) of floor space allowance with pigs per feeder were observed. Pigs with less floor space allowance had reduced BW (128.8 vs. 129.5 kg, P = 0.026), ADG (1.00 vs. 1.02 kg/d, P = 0.002), and ADFI (2.52 vs. 2.61 kg/d, P & lt; 0.001). However, G:F was improved (0.402 vs. 0.397, P = 0.039) with less floor space allowance per pig. Increased pigs per feeder space reduced final BW (129.7, 129.4, 128.4 kg, linear; P = 0.001). However, ADG had a quadratic relationship (P = 0.005) with pigs per feeder space with means of 1.03, 1.01, and 1.01 kg/d for 10, 13, and 16 pigs per feeder space. Overall, ADFI had a quadratic relationship (P & lt; 0.0001) with number of pigs per feeder space with means of 2.62, 2.52, and 2.55 kg/d for 10, 13, and 16 pigs per feeder space. Gain efficiency had a quadratic relationship (P = 0.005) with number of pigs per feeder space with means of 0.395, 0.404, and 0.400 for 10, 13, and 16 pigs per feeder space. In conclusion, a floor space allowance of 0.65 m2/pig in the grow-finish period reduced ADFI and ADG compared with 0.78 m2/pig. Overall, with the type of wet/dry feeder used in this study, 10 pigs per feeder had the greatest ADG and ADFI, compared with 13 or 16 pigs per feeder space. However, G:F improved as the number of pigs per feeder space increased.
    Type of Medium: Online Resource
    ISSN: 2573-2102
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2018
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  • 4
    In: Nutrition Research Reviews, Cambridge University Press (CUP), Vol. 36, No. 2 ( 2023-12), p. 351-371
    Abstract: Overnutrition or undernutrition during all or part of the reproductive cycle predisposes sows to metabolic consequences and poor reproductive health which contributes to a decrease in sow longevity and an increase in perinatal mortality. This represents not only an economic problem for the pig industry but also results in poor animal welfare. To maximise profitability and increase sustainability in pig production, it is pivotal to provide researchers and practitioners with synthesised information about the repercussions of maternal obesity or malnutrition on reproductive health and perinatal outcomes, and to pinpoint currently available nutritional managements to keep sows’ body condition in an optimal range. Thus, the present review summarises recent work on the consequences of maternal malnutrition and highlights new findings.
    Type of Medium: Online Resource
    ISSN: 0954-4224 , 1475-2700
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2023
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    SSG: 22
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  • 5
    Online Resource
    Online Resource
    Oxford University Press (OUP) ; 2019
    In:  Journal of Animal Science Vol. 97, No. Supplement_2 ( 2019-07-29), p. 231-231
    In: Journal of Animal Science, Oxford University Press (OUP), Vol. 97, No. Supplement_2 ( 2019-07-29), p. 231-231
    Abstract: The objective of this study was to evaluate the economically most profitable stocking density (SDEN) and the number of pigs per feeder space (PF) with a Crystal Springs wet/dry single-space double-sided feeder model F1-115. Data from a trial was used to model the optimal value. The initial trial included 3182 pigs from three consecutive grow-finish groups. The experimental treatments were designed as a two by three factorial (SDEN of 0.65 or 0.78 m2/pig with PF of 10, 13, or 16). Each pen was equipped with one double-sided wet/dry feeder, 37.5 cm wide, with one nipple drinker. Pigs with less floor space allowance had reduced ADG (1.00 versus 1.02 kg/d, P = 0.002) with improved G:F (0.402 versus 0.397, P = 0.039). Overall, ADG had a quadratic relationship (P = 0.005) with PF with means of 1.03, 1.01, and 1.01 kg/d for 10, 13, and 16 respectively. The G:F had a quadratic relationship (P = 0.005) with the number of pigs PF with means of 0.395, 0.404, and 0.400 for 10, 13, and 16 respectively. The G:F and ADG data were fitted to a regression equation including SDEN (linear) and PF (linear –quadratic). A pork production cost model was used to evaluate the impact of a range of SDEN (0.65 to 0.758 m2/pig) and PF (10 to 16) on annual profit of a grow-finish barn including feeder cost. Annual profit for a 1200 head grow-finisher was fitted to linear and quadratic regression of SDEN and PF (R2= 0.999). The optimal SDEN was 0.65 m2 per pig and 13 to 14 (13.26) PF. The differences between the maximum and the minimum net income year values for PF and PF were $4055 and $21667 USD respectively. Stocking density had a greater impact than the number of pigs per feeder space.
    Type of Medium: Online Resource
    ISSN: 0021-8812 , 1525-3163
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2019
    detail.hit.zdb_id: 390959-1
    detail.hit.zdb_id: 1490550-4
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  • 6
    In: Frontiers in Veterinary Science, Frontiers Media SA, Vol. 5 ( 2018-9-21)
    Type of Medium: Online Resource
    ISSN: 2297-1769
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2018
    detail.hit.zdb_id: 2834243-4
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  • 7
    In: PLOS ONE, Public Library of Science (PLoS), Vol. 13, No. 12 ( 2018-12-20), p. e0209569-
    Type of Medium: Online Resource
    ISSN: 1932-6203
    Language: English
    Publisher: Public Library of Science (PLoS)
    Publication Date: 2018
    detail.hit.zdb_id: 2267670-3
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  • 8
    Online Resource
    Online Resource
    Frontiers Media SA ; 2022
    In:  Frontiers in Veterinary Science Vol. 9 ( 2022-6-30)
    In: Frontiers in Veterinary Science, Frontiers Media SA, Vol. 9 ( 2022-6-30)
    Abstract: Copy number variation (CNV) has been considered to be an important source of genetic variation for important phenotypic traits of livestock. In this study, we performed whole-genome CNV detection on Suhuai (SH) ( n = 23), Chinese Min Zhu (MZ) ( n = 11), and Large White (LW) ( n = 12) pigs based on next-generation sequencing data. The copy number variation regions (CNVRs) were annotated and analyzed, and 10,885, 10,836, and 10,917 CNVRs were detected in LW, MZ, and SH pigs, respectively. Some CNVRs have been randomly selected for verification of the variation type by real-time PCR. We found that SH and LW pigs are closely related, while MZ pigs are distantly related to the SH and LW pigs by CNVR-based genetic structure, PCA, V ST , and QTL analyses. A total of 14 known genes annotated in CNVRs were unique for LW pigs. Among them, the cyclin T2 (CCNT2) is involved in cell proliferation and the cell cycle. The FA Complementation Group M (FANCM) is involved in defective DNA repair and reproductive cell development. Ten known genes annotated in 47 CNVRs were unique for MZ pigs. The genes included glycerol-3-phosphate acyltransferase 3 (GPAT3) is involved in fat synthesis and is essential to forming the glycerol triphosphate. Glutathione S-transferase mu 4 (GSTM4) gene plays an important role in detoxification. Eleven known genes annotated in 23 CNVRs were unique for SH pigs. Neuroligin 4 X-linked (NLGN4X) and Neuroligin 4 Y-linked (NLGN4Y) are involved with nerve disorders and nerve signal transmission. IgLON family member 5 (IGLON5) is related to autoimmunity and neural activities. The unique characteristics of LW, MZ, and SH pigs are related to these genes with CNV polymorphisms. These findings provide important information for the identification of candidate genes in the molecular breeding of pigs.
    Type of Medium: Online Resource
    ISSN: 2297-1769
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2834243-4
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  • 9
    In: Genetics Selection Evolution, Springer Science and Business Media LLC, Vol. 53, No. 1 ( 2021-12)
    Abstract: There is an increasing need to account for genotype-by-environment (G × E) interactions in livestock breeding programs to improve productivity and animal welfare across environmental and management conditions. This is even more relevant for pigs because selection occurs in high-health nucleus farms, while commercial pigs are raised in more challenging environments. In this study, we used single-step homoscedastic and heteroscedastic genomic reaction norm models (RNM) to evaluate G × E interactions in Large White pigs, including 8686 genotyped animals, for reproduction (total number of piglets born, TNB; total number of piglets born alive, NBA; total number of piglets weaned, NW), growth (weaning weight, WW; off-test weight, OW), and body composition (ultrasound muscle depth, MD; ultrasound backfat thickness, BF) traits. Genetic parameter estimation and single-step genome-wide association studies (ssGWAS) were performed for each trait. Results The average performance of contemporary groups (CG) was estimated and used as environmental gradient in the reaction norm analyses. We found that the need to consider heterogeneous residual variance in RNM models was trait dependent. Based on estimates of variance components of the RNM slope and of genetic correlations across environmental gradients, G × E interactions clearly existed for TNB and NBA, existed for WW but were of smaller magnitude, and were not detected for NW, OW, MD, and BF. Based on estimates of the genetic variance explained by the markers in sliding genomic windows in ssGWAS, several genomic regions were associated with the RNM slope for TNB, NBA, and WW, indicating specific biological mechanisms underlying environmental sensitivity, and dozens of novel candidate genes were identified. Our results also provided strong evidence that the X chromosome contributed to the intercept and slope of RNM for litter size traits in pigs. Conclusions We provide a comprehensive description of G × E interactions in Large White pigs for economically-relevant traits and identified important genomic regions and candidate genes associated with GxE interactions on several autosomes and the X chromosome. Implementation of these findings will contribute to more accurate genomic estimates of breeding values by considering G × E interactions, in order to genetically improve the environmental robustness of maternal-line pigs.
    Type of Medium: Online Resource
    ISSN: 1297-9686
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2021
    detail.hit.zdb_id: 2012369-3
    SSG: 12
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  • 10
    In: Genetics Selection Evolution, Springer Science and Business Media LLC, Vol. 55, No. 1 ( 2023-12-21)
    Abstract: Automatic and continuous recording of vaginal temperature (T V ) using wearable sensors causes minimal disruptions to animal behavior and can generate data that enable the evaluation of temporal body temperature variation under heat stress (HS) conditions. However, the genetic basis of T V in lactating sows from a longitudinal perspective is still unknown. The objectives of this study were to define statistical models and estimate genetic parameters for T V in lactating sows using random regression models, and identify genomic regions and candidate genes associated with HS indicators derived from automatically-recorded T V . Results Heritability estimates for T V ranged from 0.14 to 0.20 over time (throughout the day and measurement period) and from 0.09 to 0.18 along environmental gradients (EG, − 3.5 to 2.2, which correspond to dew point values from 14.87 to 28.19 ˚C). Repeatability estimates of T V over time and along EG ranged from 0.57 to 0.66 and from 0.54 to 0.77, respectively. T V measured from 12h00 to 16h00 had moderately high estimates of heritability (0.20) and repeatability (0.64), indicating that this period might be the most suitable for recording T V for genetic selection purposes. Significant genotype-by-environment interactions (GxE) were observed and the moderately high estimates of genetic correlations between pairs of extreme EG indicate potential re-ranking of selection candidates across EG. Two important genomic regions on chromosomes 10 (59.370–59.998 Mb) and16 (21.548–21.966 Mb) were identified. These regions harbor the genes CDC123 , CAMK1d , SEC61A2 , and NUDT5 that are associated with immunity, protein transport, and energy metabolism. Across the four time-periods, respectively 12, 13, 16, and 10 associated genomic regions across 14 chromosomes were identified for T V . For the three EG classes, respectively 18, 15, and 14 associated genomic windows were identified for T V , respectively. Each time-period and EG class had uniquely enriched genes with identified specific biological functions, including regulation of the nervous system, metabolism and hormone production. Conclusions T V is a heritable trait with substantial additive genetic variation and represents a promising indicator trait to select pigs for improved heat tolerance. Moderate GxE for T V exist, indicating potential re-ranking of selection candidates across EG. T V is a highly polygenic trait regulated by a complex interplay of physiological, cellular and behavioral mechanisms.
    Type of Medium: Online Resource
    ISSN: 1297-9686
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
    detail.hit.zdb_id: 2012369-3
    SSG: 12
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