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  • 1
    Online Resource
    Online Resource
    Springer Science and Business Media LLC ; 2006
    In:  Journal of Biological Physics Vol. 32, No. 6 ( 2006-12), p. 473-488
    In: Journal of Biological Physics, Springer Science and Business Media LLC, Vol. 32, No. 6 ( 2006-12), p. 473-488
    Type of Medium: Online Resource
    ISSN: 0092-0606 , 1573-0689
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2006
    detail.hit.zdb_id: 2016734-9
    SSG: 12
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  • 2
    Online Resource
    Online Resource
    Elsevier BV ; 2019
    In:  Journal of Stomatology, Oral and Maxillofacial Surgery Vol. 120, No. 2 ( 2019-04), p. 99-105
    In: Journal of Stomatology, Oral and Maxillofacial Surgery, Elsevier BV, Vol. 120, No. 2 ( 2019-04), p. 99-105
    Type of Medium: Online Resource
    ISSN: 2468-7855
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2019
    detail.hit.zdb_id: 2916276-2
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  • 3
    In: Journal of Cranio-Maxillofacial Surgery, Elsevier BV, Vol. 40, No. 5 ( 2012-7), p. 421-426
    Type of Medium: Online Resource
    ISSN: 1010-5182
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2012
    detail.hit.zdb_id: 2009565-X
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  • 4
    In: Journal of Cranio-Maxillofacial Surgery, Elsevier BV, Vol. 41, No. 3 ( 2013-4), p. 235-241
    Type of Medium: Online Resource
    ISSN: 1010-5182
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2013
    detail.hit.zdb_id: 2009565-X
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  • 5
    Online Resource
    Online Resource
    Wiley ; 2009
    In:  Journal of Periodontology Vol. 80, No. 12 ( 2009-12), p. 1998-2009
    In: Journal of Periodontology, Wiley, Vol. 80, No. 12 ( 2009-12), p. 1998-2009
    Abstract: Background: Tentative bioinformatic predictions were performed to comprehend the complexity of the gene interaction networks of the T lymphocyte cell cycle and of human periodontitis. This study aims to identify and rank genes involved in osseous augmentation or bone remodeling to obtain groups with more numerous predicted associations called the leader gene clusters. Methods: An iterative search (consisting of a consecutive expansion‐filtering loop) was performed for which only genes involved in a specific process were identified. For each gene, predicted associations with all other involved genes were obtained from a Web‐available database (Search Tool for the Retrieval of Interacting Genes/Proteins) and the weighted number of links (WNL), given by the sum of only high‐confidence predicted associations (results with a score ≥0.9), allowing gene ranking. Genes belonging to higher clustering classes were identified. Results: A total of 161 genes potentially involved in bone‐volume augmentation and 128 genes connected with the bone‐remodeling phenomenon were identified. For the bone‐volume augmentation process, only one gene belonged to the leader gene group, whereas six other genes were classified as cluster B genes; for the bone‐remodeling phenomenon, three leader genes were identified, whereas six other genes formed the cluster B group. No one gene belonged to leader gene clusters of both processes, whereas one gene of each higher cluster group belonged to the immediately lower cluster of the opposite process. Only three genes of the higher clusters were experimentally involved in both analyses. Conclusions: A de novo identification was performed based on the data mining of leader genes involved in bone‐volume augmentation or bone remodeling to acquire primeval information about their molecular basis and to plan future ad hoc targeted experiments. For several genes of the upper clusters, an active role in the bone processes was already known, but the present analysis suggested that they play a major role in the analyzed phenomena. The role of the transcription factors as leader genes and the numerous orphan genes (genes with WNL = 0) recovered probably attest to a lack of information regarding these processes, which could be further clarified through specific DNA microarray experiments.
    Type of Medium: Online Resource
    ISSN: 0022-3492 , 1943-3670
    Language: English
    Publisher: Wiley
    Publication Date: 2009
    detail.hit.zdb_id: 2040047-0
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  • 6
    In: Clinical Implant Dentistry and Related Research, Wiley, Vol. 19, No. 6 ( 2017-12), p. 1044-1053
    Abstract: Alveolar ridge volume loss may be minimized when postextraction sockets are filled by bone substitutes. Purpose The aim of the study was to measure the effect of alveolar ridge preservation (ARP) in maintaining the external contour of the ridge after fresh socket grafting with or without particulate anorganic bovine bone mineral (BBM) and resorbable barrier covering. Materials and methods In the present controlled study, patients subjected to single‐tooth extraction were allocated to 2 groups: postextraction sockets grafted with bovine bone mineral ( bbm ), and naturally healing sockets ( nat ). Before and at 5 months following tooth extraction, plaster cast contours of the sockets were acquired by means of an optical scanner; the 2 contours of each patient underwent voxelization and fusion using a matrix elaborator. Outcome variables at 5 months (volumetric, surface, and linear changes) were measured in digital fused plaster casts with a dental scan software analyzing a volume of interest ranging from residual papilla to 10 mm toward the apical point. Intra‐ and inter‐group pair‐wise variables' comparisons were conducted. Level of significance was set at 0.05. Results Twenty‐four sites were enrolled: 12 ARP and 12 naturally healed. Five‐month percentage of volume loss of the bbm ‐group (21.7% ± 7.4%) was significantly lower ( P s  〈  .0003) than that of the naturally healing group (38.8% ± 7.9%). When tooth position was investigated, volume loss in percentage registered a significantly better ( P values ≤ .0485) behavior in molars (ΔV% = −19.1% ± 6.5% and ΔV% = −35.6% ± 7.6%, respectively, for bbm and nat ) than that in premolars (ΔV% = −26.9% ± 7.2% and ΔV% = −45.1% ± 4.2%, respectively, for bbm and nat ), in both the preserved and naturally healing groups. Conclusion The dimensional loss in postextraction sockets grafted with anorganic bovine bone substitute and covered by a resorbable collagen barrier was lower than that of the naturally healing sites. However, ridge preservation was able to maintain almost 80% of the pristine bone.
    Type of Medium: Online Resource
    ISSN: 1523-0899 , 1708-8208
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2017
    detail.hit.zdb_id: 2094120-1
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  • 7
    Online Resource
    Online Resource
    American Academy of Implant Dentistry ; 2015
    In:  Journal of Oral Implantology Vol. 41, No. 5 ( 2015-10-01), p. 570-578
    In: Journal of Oral Implantology, American Academy of Implant Dentistry, Vol. 41, No. 5 ( 2015-10-01), p. 570-578
    Abstract: The purpose of this study is to analyze marginal bone levels (MBLs) around dental implants positioned in the upper and lower jaw with or without horizontal onlay grafting procedures, and to survey implant survival with a follow-up of 5 years. Seventeen patients were surveyed in the present retrospective chart review. A total of 27 dental implants positioned in pristine bone and 21 in horizontally grafted bone were enrolled. MBLs were recorded for 4 aspects during a radiologic survey of 5 years. Significant differences were searched for among times and surgical procedures with paired and unpaired comparison tests, respectively, and survival rates were calculated for the 2 groups. In the maxilla, no statistically-significant differences between pristine and augmented groups were obtained; the time comparisons for pristine implants showed an affection of palatal, mesial, and distal sides, whereas the resorption around implants placed into horizontally grafted bone of anterior maxilla seemed to be limited just to buccal and distal aspects. Comparisons with the pristine horizontal procedure revealed that just the buccal sides were involved. The analysis of time comparisons attested to a continuous alveolar bone remodeling during the entire time of the survey for the pristine group. Given the extremely unfavorable resorption at the buccal aspect of the augmented areas, clinicians should reserve dental implant positioning into horizontal bone graft to selected patients, in whom it may represent one of the last opportunities of rehabilitation with a fixed prosthesis.
    Type of Medium: Online Resource
    ISSN: 1548-1336 , 0160-6972
    Language: English
    Publisher: American Academy of Implant Dentistry
    Publication Date: 2015
    detail.hit.zdb_id: 2139588-3
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  • 8
    Online Resource
    Online Resource
    Elsevier BV ; 2013
    In:  Archives of Oral Biology Vol. 58, No. 8 ( 2013-8), p. 912-929
    In: Archives of Oral Biology, Elsevier BV, Vol. 58, No. 8 ( 2013-8), p. 912-929
    Type of Medium: Online Resource
    ISSN: 0003-9969
    RVK:
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2013
    detail.hit.zdb_id: 1496079-5
    SSG: 12
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  • 9
    In: Clinical Oral Implants Research, Wiley, Vol. 27, No. 9 ( 2016-09), p. 1152-1159
    Abstract: The aim of the study was to analyze volume changes of post‐extractive sockets grafted with or without deproteinized bovine bone mineral ( DBBM ) and a resorbable barrier. Materials and methods This retrospective analysis utilized patients who had undergone tooth extraction. Sites, one per patient, were allocated to two groups: post‐extractive non‐grafted sockets ( NG ) and post‐extractive grafted sockets with DBBM and resorbable barrier insertion (G). Maximal primary soft tissue closure was sought for both procedures. Before extraction and 6 months later, three‐dimensional features of the sockets (linear indexes, areas, and volumes) and outcome variables at 6 months (volume‐ and surface changes) were acquired through computer tomography scans. Intra‐ and inter‐group comparisons of the outcome variables were performed. Nonparametric tests were applied with a level of significance set at P   〈  0.01. Results Twenty‐four sites, 9 grafted and 15 ungrafted, were enrolled. Between baseline and the 6‐month evaluation, significant bone volume loss, superior surface shrinkage, and height reduction were registered for the G (72 mm 3 , 76 mm 2 , and 0.5 mm, respectively) and the NG group (274 mm 3 , 87 mm 2 , and 1.8 mm, respectively) with all P ‐values ≤ 0.0039. A significant difference, regarding the percentage of the volume change, was registered between the two procedures with a volume loss of 9.9% for the grafted sockets and 34.8% for the ungrafted ones ( P ‐value = 0.0073). Conclusion Grafting of the sockets with DBBM and a resorbable barrier insertion seemed to reduce negative osseous remodeling in the short term when compared to that of the ungrafted sockets.
    Type of Medium: Online Resource
    ISSN: 0905-7161 , 1600-0501
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2016
    detail.hit.zdb_id: 2027104-9
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  • 10
    In: Clinical Oral Implants Research, Wiley, Vol. 25, No. 9 ( 2014-09), p. 1056-1064
    Abstract: The present study analysed apical and marginal bone remodelling around dental implants placed in both maxillary (sinus elevated with particulated autogenous osseous graft) and corresponding native bone areas, with a follow‐up of 5 years. The clinical survival of implants was also observed. Materials and methods In this retrospective chart review, 27 patients were enrolled, with 55 dental implants inserted from 2000 to 2006, 26 of which were followed (one implant per patient); if required, patients were treated via sinus lift with autogenous bone and particulate technique. The internal controls were implants positioned in native areas beneath the sinus. Radiologic survey was assessed via computerized tomographic analysis measuring apical bone level ( ABL ) and marginal bone level ( MBL ), at 1‐ (T 1 ), 3‐ (T 2 ) and 5 years (T 3 ), around implants (buccal, b ; palatal, p ; mesial, m ; and distal sides, d ). Clinical probing depth ( CPD ) and clinical attachment level ( CAL ) for all the four peri‐implant aspects were measured. Cumulative survival rate ( CSR ) and survival rate ( SR ) of implants were calculated. Significances for paired and unpaired comparisons were searched for. Results A significant degree of apical resorption was recorded between T 1 and T 3 for the mesial particulate group; again, a significant difference was discovered between the native and particulate procedures for m ABL . A further feature was discovered for the particulate procedure, for which ABLs resulted negative at least for three of the aspects. Regarding MBL measurements, similar behaviours were revealed using time‐comparison analysis for the two procedures at the buccal aspect. Comparisons among diameters, irrespective of the procedure, showed that resorption times for the b MBL were shorter as the diameter of the implant became wider. The implant CSR was 92% in native areas (two failures/25 implants) and 93.3% in sinuses lifted with particulate bone (two failures/30 implants). Conclusions The results suggest that a protrusion of the implant apices into augmented sinus lift occurred, whereas the bone remodelling of the coronal areas was not influenced by the events in the maxillary sinus. A diameter ranging from 4 to 5 mm might better guarantee a conservation of marginal peri‐implant bone level compared with implants with smaller diameters.
    Type of Medium: Online Resource
    ISSN: 0905-7161 , 1600-0501
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2014
    detail.hit.zdb_id: 2027104-9
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