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  • 1
    Online Resource
    Online Resource
    Elsevier BV ; 2011
    In:  Annals of Physics Vol. 326, No. 2 ( 2011-02), p. 463-485
    In: Annals of Physics, Elsevier BV, Vol. 326, No. 2 ( 2011-02), p. 463-485
    Type of Medium: Online Resource
    ISSN: 0003-4916
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2011
    detail.hit.zdb_id: 1461336-0
    detail.hit.zdb_id: 211006-4
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  • 2
    Online Resource
    Online Resource
    Elsevier BV ; 2011
    In:  Annals of Physics Vol. 326, No. 2 ( 2011-02), p. 440-462
    In: Annals of Physics, Elsevier BV, Vol. 326, No. 2 ( 2011-02), p. 440-462
    Type of Medium: Online Resource
    ISSN: 0003-4916
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2011
    detail.hit.zdb_id: 1461336-0
    detail.hit.zdb_id: 211006-4
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  • 3
    Online Resource
    Online Resource
    IOP Publishing ; 2018
    In:  Journal of Cosmology and Astroparticle Physics Vol. 2018, No. 12 ( 2018-12-04), p. 004-004
    In: Journal of Cosmology and Astroparticle Physics, IOP Publishing, Vol. 2018, No. 12 ( 2018-12-04), p. 004-004
    Type of Medium: Online Resource
    ISSN: 1475-7516
    Language: Unknown
    Publisher: IOP Publishing
    Publication Date: 2018
    detail.hit.zdb_id: 2104147-7
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  • 4
    Online Resource
    Online Resource
    IOP Publishing ; 2005
    In:  Journal of Cosmology and Astroparticle Physics Vol. 2005, No. 01 ( 2005-01-13), p. 006-006
    In: Journal of Cosmology and Astroparticle Physics, IOP Publishing, Vol. 2005, No. 01 ( 2005-01-13), p. 006-006
    Type of Medium: Online Resource
    ISSN: 1475-7516
    Language: Unknown
    Publisher: IOP Publishing
    Publication Date: 2005
    detail.hit.zdb_id: 2104147-7
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  • 5
    Online Resource
    Online Resource
    American Physical Society (APS) ; 2018
    In:  Physical Review Letters Vol. 121, No. 16 ( 2018-10-19)
    In: Physical Review Letters, American Physical Society (APS), Vol. 121, No. 16 ( 2018-10-19)
    Type of Medium: Online Resource
    ISSN: 0031-9007 , 1079-7114
    RVK:
    RVK:
    Language: English
    Publisher: American Physical Society (APS)
    Publication Date: 2018
    detail.hit.zdb_id: 1472655-5
    detail.hit.zdb_id: 208853-8
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  • 6
    Online Resource
    Online Resource
    Springer Science and Business Media LLC ; 2023
    In:  Journal of High Energy Physics Vol. 2023, No. 9 ( 2023-09-11)
    In: Journal of High Energy Physics, Springer Science and Business Media LLC, Vol. 2023, No. 9 ( 2023-09-11)
    Abstract: The gravitational asymptotic safety program envisions a high-energy completion of gravity based on a non-Gaussian renormalization group fixed point. A key step in this program is the transition from Euclidean to Lorentzian signature spacetimes. One way to address this challenge is to formulate the quantum theory based on the Arnowitt-Deser-Misner decomposition of the metric field. This equips the Euclidean spacetime with a preferred direction which may serve as the time-direction in the Lorentzian setting. In this work we use the Wetterich equation in order to compute the renormalization group flow of the graviton two-point function. The resulting beta functions possess a non-Gaussian renormalization group fixed point suitable for rendering the theory asymptotically safe. The phase diagram underlying the flow of the two-point function is governed by the interplay between this non-Gaussian fixed point, the Gaussian fixed point, and an infrared fixed point. The latter ensures that the renormalized squared graviton mass cannot take negative values. These results are in qualitative agreement with fluctuation computations carried out in the covariant setting. We take this as non-trivial evidence that the asymptotic safety mechanism remains intact when considering quantum gravity on spacetimes carrying a foliation structure. Technically, our work constitutes the first fluctuation computation carried out within the ADM-framework. Therefore, we also provide a detailed discussion of the conceptual framework, highlighting the elements which differ from fluctuation computations in the covariant setting.
    Type of Medium: Online Resource
    ISSN: 1029-8479
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
    detail.hit.zdb_id: 2027350-2
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  • 7
    In: British Journal of Sports Medicine, BMJ, Vol. 56, No. 21 ( 2022-11), p. 1241-1251
    Abstract: Compare the effectiveness of primarily surgical versus primarily rehabilitative management for anterior cruciate ligament (ACL) rupture. Design Living systematic review and meta-analysis. Data sources Six databases, six trial registries and prior systematic reviews. Forward and backward citation tracking was employed. Eligibility criteria Randomised controlled trials that compared primary reconstructive surgery and primary rehabilitative treatment with or without optional reconstructive surgery. Data synthesis Bayesian random effects meta-analysis with empirical priors for the OR and standardised mean difference and 95% credible intervals (CrI), Cochrane RoB2, and the Grading of Recommendations Assessment, Development and Evaluation approach to judge the certainty of evidence. Results Of 9514 records, 9 reports of three studies (320 participants in total) were included. No clinically important differences were observed at any follow-up for self-reported knee function (low to very low certainty of evidence). For radiological knee osteoarthritis, we found no effect at very low certainty of evidence in the long term (OR (95% CrI): 1.45 (0.30 to 5.17), two studies). Meniscal damage showed no effect at low certainty of evidence (OR: 0.85 (95% CI 0.45 to 1.62); one study) in the long term. No differences were observed between treatments for any other secondary outcome. Three ongoing randomised controlled trials were identified. Conclusions There is low to very low certainty of evidence that primary rehabilitation with optional surgical reconstruction results in similar outcome measures as early surgical reconstruction for ACL rupture. The findings challenge a historical paradigm that anatomic instability should be addressed with primary surgical stabilisation to provide optimal outcomes. PROSPERO registration number CRD42021256537.
    Type of Medium: Online Resource
    ISSN: 0306-3674 , 1473-0480
    Language: English
    Publisher: BMJ
    Publication Date: 2022
    detail.hit.zdb_id: 2003204-3
    SSG: 31
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  • 8
    Online Resource
    Online Resource
    Georg Thieme Verlag KG ; 2022
    In:  Sportverletzung · Sportschaden Vol. 36, No. 01 ( 2022-03), p. 18-37
    In: Sportverletzung · Sportschaden, Georg Thieme Verlag KG, Vol. 36, No. 01 ( 2022-03), p. 18-37
    Abstract: Einleitung Die Behandlung einer vorderen Kreuzbandruptur wird nach wie vor kontrovers diskutiert. Insbesondere die Frage: Konservative oder operative Versorgung? steht dabei im Mittelpunkt. Für die Beantwortung dieser Frage werden häufig Folgeschäden wie die Entwicklung einer posttraumatischen Arthrose, Sekundärschäden am Meniskus oder Knorpel und auch die Partizipation im Sport herangezogen. Sollten zwischen den einzelnen Behandlungsoptionen bedeutsame Unterschiede bezüglich dieser Parameter bestehen, so wären die Ergebnisse für die Entwicklung evidenzbasierter Behandlungspfade von hoher Bedeutung. Ziel dieser Arbeit war es daher, die Entwicklung einer Gonarthrose nach einer Ruptur des vorderen Kreuzbandes und der entsprechenden Behandlung (konservativ oder operativ) zu evaluieren. Material und Methoden Zur Beantwortung der Fragestellung wurde eine systematische Literaturrecherche in der Medline über Pubmed, der Cochrane Library und in CINAHL durchgeführt. Die Recherche wurde im Januar 2020 durchgeführt und im Januar 2021 wiederholt. Eingeschlossen wurden ausschließlich systematische Reviews mit einem minimalen Nachuntersuchungszeitraum von 10 Jahren. Untersuchte Kohorten umfassten Patienten mit einer entweder konservativ oder operativ versorgten Ruptur des vorderen Kreuzbandes. Die Diagnose Arthrose wurde entweder radiologisch (anerkannte Scores) oder klinisch (Schmerz und Funktionseinschränkung) gestellt. Passende Übersichtsarbeiten wurden mit dem AMSTAR-2-Fragebogen einer qualitativen Bewertung unterzogen. Ergebnisse Die Literaturrecherche ermittelte zunächst n = 42 Übersichtsarbeiten, von denen 14 Arbeiten inkludiert werden konnten. Nach der Volltextprüfung und der qualitativen Bewertung verblieben zur Auswertung der Ergebnisse lediglich n = 2 systematische Reviews. Die Ergebnisse beider Arbeiten zeigen unpräzise Daten mit einer großen Variabilität. Es kann aber mit großer Wahrscheinlichkeit davon ausgegangen werden, dass das Risiko für die Entwicklung einer Gonarthrose nach einer Ruptur des vorderen Kreuzbandes erhöht ist. Eine Reduktion der Inzidenz der Gelenkdegeneration durch eine Rekonstruktion des vorderen Kreuzbandes ist nicht nachweisbar, genauso wenig wie ein Unterschied bei einem direkten Vergleich zwischen konservativer und operativer Versorgung. Schlussfolgerung Patienten mit einer vorderen Kreuzbandruptur tragen mit hoher Wahrscheinlichkeit ein größeres Risiko für eine progressive Gelenkdegeneration. Ein pauschaler protektiver Effekt einer Kreuzbandplastik ist in den ausgewerteten Arbeiten nicht nachweisbar. Aus diesem Grund sollten innerhalb der Entscheidungsfindung über operative versus konservative Versorgung andere Faktoren wie die funktionelle Instabilität noch höher bewertet werden.
    Type of Medium: Online Resource
    ISSN: 0932-0555 , 1439-1236
    RVK:
    Language: German
    Publisher: Georg Thieme Verlag KG
    Publication Date: 2022
    detail.hit.zdb_id: 639120-5
    detail.hit.zdb_id: 2041799-8
    SSG: 31
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  • 9
    Online Resource
    Online Resource
    World Scientific Pub Co Pte Ltd ; 2009
    In:  Modern Physics Letters A Vol. 24, No. 28 ( 2009-09-14), p. 2233-2241
    In: Modern Physics Letters A, World Scientific Pub Co Pte Ltd, Vol. 24, No. 28 ( 2009-09-14), p. 2233-2241
    Abstract: We study the nonperturbative renormalization group flow of higher-derivative gravity employing functional renormalization group techniques. The nonperturbative contributions to the β-functions shift the known perturbative ultraviolet fixed point into a nontrivial fixed point with three UV-attractive and one UV-repulsive eigendirections, consistent with the asymptotic safety conjecture of gravity. The implication of this transition on the unitarity problem, typically haunting higher-derivative gravity theories, is discussed.
    Type of Medium: Online Resource
    ISSN: 0217-7323 , 1793-6632
    Language: English
    Publisher: World Scientific Pub Co Pte Ltd
    Publication Date: 2009
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  • 10
    Online Resource
    Online Resource
    World Scientific Pub Co Pte Ltd ; 2021
    In:  International Journal of Modern Physics D Vol. 30, No. 14 ( 2021-10-15)
    In: International Journal of Modern Physics D, World Scientific Pub Co Pte Ltd, Vol. 30, No. 14 ( 2021-10-15)
    Abstract: Black holes constitute some of the most fascinating objects in our universe. According to Einstein’s theory of general relativity, they are also deceivingly simple: Schwarzschild black holes are completely determined by their mass. Moreover, the singularity theorems by Penrose and Hawking indicate that they host a curvature singularity within their event horizon. The presence of the latter invites the question whether these dead-end points of spacetime can be made regular by considering (quantum) corrections to the classical field equations. In this light, we use the Frobenius method to investigate the phase space of asymptotically flat, static, and spherically symmetric black hole solutions in quadratic gravity. We argue that the only asymptotically flat black hole solution visible in this approach is the Schwarzschild solution.
    Type of Medium: Online Resource
    ISSN: 0218-2718 , 1793-6594
    Language: English
    Publisher: World Scientific Pub Co Pte Ltd
    Publication Date: 2021
    SSG: 16,12
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