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  • 1
    In: Jurnal Farmasi Sains dan Praktis, Universitas Muhammadiyah Magelang, ( 2022-01-18), p. 89-96
    Abstract: Herbal medicine as a traditional medicine based on local wisdom in the Covid 19 pandemic is the alternative for the community to keep the health of the body. Specific drugs for the cure of Covid-19 disease have also not been found yet so the death of Covid-19 patients remainsat anytime. In this case this study aims to know the content of secondary metabolite compounds and radical scavenger activity of “kayu jawa” (L. coromandelica) leaf steeping and “Salam” (S. polyanthum) leaves from Southeast Sulawesi as well as their rational combination based on the radical scavenger activity of DPPH (2,2-difenyl-1-picrilhydrazil). The analysis of the content of secondary metabolite compounds in the steeping of DKJ (Daun Kayu Jawa) and DS (Daun Salam) is applied by phytochemical method and radical scavenger activity is determined by the DPPH method. The main focus of steeping is determined by the approach of the picnometer. The combination of DKJ and DS is made each with 6 variations based on the IC50 steeping value, then converted in the form of weight (grams) of DKJ and DS powder so that 36 combinations are obtained. The result of phytochemical analysis of DKJ and DS steeping showed the presence of flavonoids, saponins and polyphenols, except tannins only exist in the steeping of DS. The radical scavenger activity of DKJ and DS steeping showed IC50 values of 408.95 ± 0.075 µg/mL and 259.05 ± 0.092 µg/mL. The combination that showed the highest DPPH radical scavenger activity of 88.050.03% occurred in the combination of E1 with a ratio of 2IC50 DK: 1/8IC50DS (1,089: 0.128) grams. DPPH radical scavenger activity approaching 50% occurs in the combination of A2 and B1 with a ratio of 1/8IC50 DKJ: ¼IC50DS (0.068:0.256) grams and ¼IC50 DKJ: 1/8IC50DS (0.136:0.128) grams with values of (49.11 0.04) % and (52.87  0.05) % respectively.
    Type of Medium: Online Resource
    ISSN: 2579-4558 , 2549-9068
    URL: Issue
    Language: Unknown
    Publisher: Universitas Muhammadiyah Magelang
    Publication Date: 2022
    Location Call Number Limitation Availability
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  • 2
    In: INDONESIAN JOURNAL OF PHARMACY, Universitas Gadjah Mada, Vol. 29, No. 1 ( 2018-04-17), p. 16-
    Type of Medium: Online Resource
    ISSN: 2338-9486 , 2338-9427
    Language: Unknown
    Publisher: Universitas Gadjah Mada
    Publication Date: 2018
    detail.hit.zdb_id: 3041414-3
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  • 3
    In: Jurnal Farmasi Sains dan Praktis, Universitas Muhammadiyah Magelang, Vol. 7, No. 3 ( 2022-01-18), p. 298-305
    Abstract: Herbal medicine as a traditional medicine based on local wisdom in the Covid 19 pandemic is the alternative for the community to keep the health of the body. Specific drugs for the cure of Covid-19 disease have also not been found yet so the death of Covid-19 patients remainsat anytime. In this case this study aims to know the content of secondary metabolite compounds and radical scavenger activity of “kayu jawa” (L. coromandelica) leaf steeping and “Salam” (S. polyanthum) leaves from Southeast Sulawesi as well as their rational combination based on the radical scavenger activity of DPPH (2,2-difenyl-1-picrilhydrazil). The analysis of the content of secondary metabolite compounds in the steeping of DKJ (Daun Kayu Jawa) and DS (Daun Salam) is applied by phytochemical method and radical scavenger activity is determined by the DPPH method. The main focus of steeping is determined by the approach of the picnometer. The combination of DKJ and DS is made each with 6 variations based on the IC50 steeping value, then converted in the form of weight (grams) of DKJ and DS powder so that 36 combinations are obtained. The result of phytochemical analysis of DKJ and DS steeping showed the presence of flavonoids, saponins and polyphenols, except tannins only exist in the steeping of DS. The radical scavenger activity of DKJ and DS steeping showed IC50 values of 408.95 ± 0.075 µg/mL and 259.05 ± 0.092 µg/mL. The combination that showed the highest DPPH radical scavenger activity of 88.050.03% occurred in the combination of E1 with a ratio of 2IC50 DK: 1/8IC50DS (1,089: 0.128) grams. DPPH radical scavenger activity approaching 50% occurs in the combination of A2 and B1 with a ratio of 1/8IC50 DKJ: ¼IC50DS (0.068:0.256) grams and ¼IC50 DKJ: 1/8IC50DS (0.136:0.128) grams with values of (49.11 0.04) % and (52.87  0.05) % respectively.
    Type of Medium: Online Resource
    ISSN: 2579-4558 , 2549-9068
    URL: Issue
    Language: Unknown
    Publisher: Universitas Muhammadiyah Magelang
    Publication Date: 2022
    Location Call Number Limitation Availability
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  • 4
    Online Resource
    Online Resource
    Universitas Muhammadiyah Gresik ; 2021
    In:  Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Vol. 3, No. 01 ( 2021-10-28), p. 34-
    In: Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS), Universitas Muhammadiyah Gresik, Vol. 3, No. 01 ( 2021-10-28), p. 34-
    Abstract: Tingkat kepuasan pasien terhadap sebuah pelayanan kefarmasian di apotek harus selalu diperbarui atau dievaluasi minimal 6 bulan sekali, tak terkecuali Apotek Kimia Farma 36 Ijen. Pelayanan kefarmasian menurut Permenkes No.73 Tahun 2016 adalah suatu pelayanan langsung dan bertanggung jawab kepada pasien yang berkaitan dengan sediaan farmasi yang bertujuan untuk mencapai hasil yang pasti agar meningkatkan mutu kehidupan pasien. Tujuan penelitian ini adalah untuk mengetahui kepuasan pasien terhadap pelayanan kefarmasian di Apotek Kimia Farma 36 Ijen. Metode penelitian yang digunakan adalah penelitian deskriptif melalui penyebaran kuesioner untuk mengukur kepuasan pasien menggunakan model SERVQUAL (Service Quality) dengan teknik incidental sampling. Hasil penelitian menyatakan bahwa analisis Gap memiliki nilai negatif yang berarti pasien tidak puas dengan pelayanan kefarmasian di Apotek Kimia Farma 36 Ijen. Dimensi yang mempunyai kepuasan tertinggi secara berturut-turut yaitu emphaty, reliability, tangible, assurance dan terakhir responsiveness. Pernyataan pada kuesioner yang mempunyai kepuasan tertinggi adalah petugas farmasi yang memperhatikan keluhan pasien, dan kepuasan terendah pada pernyataan kuesioner adalah petugas farmasi selalu menyelesaikan masalah pasien. Hasil analisis diagram Kartesius tidak ada pernyataan kuesioner yang masuk pada kuadran A dan D, 7 item pernyataan pada kuadran B, dan 8 item penyataan pada kuadran C. Kata Kunci: Kepuasan pasien; Pelayanan Kefarmasian; Apotek Kimia Farma 36 Ijen
    Type of Medium: Online Resource
    ISSN: 2715-0518 , 2715-3053
    URL: Issue
    Language: Unknown
    Publisher: Universitas Muhammadiyah Gresik
    Publication Date: 2021
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