In:
Chemical Communications, Royal Society of Chemistry (RSC), Vol. 57, No. 88 ( 2021), p. 11701-11704
Abstract:
A novel aza-Prins type cyclization reaction involving N -acyliminium ions and amides is reported for the synthesis of tetrahydropyrimido[2,1- a ]isoindole-2,6-dione and 6,6 a -dihydroisoindolo[2,1- a ]quinazoline-5,11-dione derivatives in excellent yields. The strategy features inexpensive reagents, mild reaction conditions, and metal-free synthesis of N-heterocyclic frameworks. Further, post-synthetic modification results in the unprecedented formation of its triazole, tetracyclic diazacyclopenta[ def ]phenanthrene-1,4(9 a 1 H )-dione and carbonyl derivatives.
Type of Medium:
Online Resource
ISSN:
1359-7345
,
1364-548X
Language:
English
Publisher:
Royal Society of Chemistry (RSC)
Publication Date:
2021
detail.hit.zdb_id:
1472881-3
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