In:
Gastroenterology Research and Practice, Hindawi Limited, Vol. 2017 ( 2017), p. 1-11
Abstract:
Objective . To compare the differences between acute colonic pseudo-obstruction (ACPO) with and without acute gut wall thickening. Methods . ACPO patients with feeding tolerance were divided into ACPO with no obvious gut wall thickening (ACPO-NT) group and ACPO with obvious acute gut wall thickening (ACPO-T) group according to computed tomography and abdominal radiographs. Patients’ condition, responses to supportive measures, pharmacologic therapy, endoscopic decompression, and surgeries and outcomes were compared. Results . Patients in ACPO-T group had a significantly higher APACHE II (11.82 versus 8.25, p = 0.008 ) and SOFA scores (6.47 versus 3.54, p 〈 0.001 ) and a significantly higher 28-day mortality (17.78% versus 4.16%, p = 0.032 ) and longer intensive care unit stage (4 versus 16 d, p 〈 0.001 ). Patients in ACPO-NT group were more likely to be responsive to supportive treatment (62.50% versus 24.44%, p 〈 0.001 ), neostigmine (77.78% versus 17.64%, p 〈 0.001 ), and colonoscopic decompression (75% versus 42.86%, p = 0.318 ) than those in ACPO-T group. Of the patients who underwent ileostomy, 81.25% gained benefits. Conclusions . ACPO patients with gut wall thickening are more severe and are less likely to be responsive to nonsurgical treatment. Ileostomy may be a good option for ACPO patients with gut wall thickening who are irresponsive to nonsurgical treatment.
Type of Medium:
Online Resource
ISSN:
1687-6121
,
1687-630X
DOI:
10.1155/2017/9574592
Language:
English
Publisher:
Hindawi Limited
Publication Date:
2017
detail.hit.zdb_id:
2435460-0
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