In:
Annals of Otology, Rhinology & Laryngology, SAGE Publications, Vol. 101, No. 10_suppl ( 1992-10), p. 72-77
Abstract:
Tissues of the stria vascularis of normal rabbits were collected as cochlear antigen and injected into the foot pad of guinea pigs. The mechanism of development of endolymphatic hydrops was studied by the tracer method. Damage to the capillary endothelium and an increase in vascular permeability were found in the stria vascularis. Therefore, we studied patients with a raised level of immunoglobulin (Ig) G—class circulating immune complexes (CICs). Hearing loss was found in 3 of 22 patients with significantly elevated IgG CIC levels (13.6%). The relationship between inner ear disease and the presence of CIC was considered to be very significant. The possible mechanism of CIC-mediated inner ear diseases is discussed.
Type of Medium:
Online Resource
ISSN:
0003-4894
,
1943-572X
DOI:
10.1177/0003489492101S1015
Language:
English
Publisher:
SAGE Publications
Publication Date:
1992
detail.hit.zdb_id:
2033055-8
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